Best TWAS P=1.66e-08 · Best GWAS P=5.07e-09 conditioned to 0.0833
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Artery Tibial | UFL1 | 0.08 | 0.05 | lasso | 4 | 0.04 | 7.9e-04 | 5.5 | 5.5 | 3.5e-08 | 0.98 | 0.03 | 0.96 | FALSE |
| 2 | GTEx | Nerve Tibial | UFL1 | 0.09 | 0.11 | lasso | 8 | 0.08 | 2.8e-06 | 5.3 | 5.2 | 1.9e-07 | 0.93 | 0.06 | 0.94 | FALSE |
| 3 | GTEx | Pancreas | UFL1 | 0.08 | 0.11 | enet | 7 | 0.09 | 1.1e-04 | 5.6 | 5.6 | 1.7e-08 | 0.91 | 0.03 | 0.94 | TRUE |
| 4 | GTEx | Thyroid | UFL1 | 0.06 | 0.00 | lasso | 2 | 0.00 | 6.6e-01 | 5.7 | 5.2 | 1.8e-07 | 0.95 | 0.03 | 0.86 | FALSE |
| 5 | The Cancer Genome Atlas | Lung Adenocarcinoma | FHL5 | 0.03 | 0.02 | blup | 55 | 0.01 | 7.1e-03 | 5.5 | -5.2 | 2.3e-07 | -0.92 | 0.01 | 0.87 | FALSE |
| 6 | The Cancer Genome Atlas | Thyroid Carcinoma | KIAA0776 | 0.05 | 0.07 | lasso | 2 | 0.06 | 1.8e-06 | 5.3 | 5.2 | 2.5e-07 | 0.94 | 0.01 | 0.99 | FALSE |