Best TWAS P=1.45e-10 · Best GWAS P=2.86e-13 conditioned to 6.57e-05
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | NOC3L | 0.10 | 0.11 | lasso | 5 | 0.12 | 4.7e-14 | -4.4 | -5.2 | 2.3e-07 | 0.43 | 0.99 | 0.01 | FALSE |
| 2 | GTEx | Muscle Skeletal | NOC3L | 0.09 | 0.05 | enet | 7 | 0.05 | 7.5e-06 | -4.4 | -6.4 | 1.4e-10 | 0.69 | 0.09 | 0.89 | TRUE |
| 3 | The Cancer Genome Atlas | Pancreatic Adenocarcinoma | NOC3L | 0.08 | 0.06 | lasso | 2 | 0.04 | 5.8e-03 | -5.9 | -5.9 | 3.9e-09 | 0.46 | 0.02 | 0.52 | FALSE |