[Hub]/) : Traits : Hypertension (Self-reported) : ← →

chr1:112,312,154-113,941,737

Best TWAS P=5.44e-17 · Best GWAS P=8.47e-22 conditioned to 1.66e-10

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex WNT2B 0.43 0.46 enet 44 0.47 7.4e-64 4.60 5.4 6.2e-08 0.33 1.00 0.00 FALSE
2 GTEx Adipose Subcutaneous WNT2B 0.10 0.10 enet 19 0.06 1.2e-05 -4.71 -5.9 3.3e-09 -0.12 1.00 0.00 FALSE
3 GTEx Artery Aorta WNT2B 0.15 0.01 enet 7 0.01 1.0e-01 -5.79 -5.8 5.4e-09 -0.16 0.24 0.04 FALSE
4 GTEx Breast Mammary Tissue (Male) WNT2B 0.18 0.07 lasso 6 0.05 2.3e-02 -5.73 -6.1 1.1e-09 -0.16 0.08 0.05 FALSE
5 GTEx Breast Mammary Tissue (Female) WNT2B 0.01 -0.01 enet 24 0.00 3.4e-01 0.91 -5.3 1.1e-07 -0.11 0.03 0.05 FALSE
6 GTEx Muscle Skeletal WNT2B 0.06 0.02 lasso 7 0.03 9.4e-04 -5.71 -7.0 2.2e-12 -0.14 0.56 0.02 FALSE
7 GTEx Nerve Tibial RP4-671G15.2 0.07 0.06 lasso 2 0.06 2.9e-05 -5.21 5.5 4.3e-08 0.17 0.94 0.00 FALSE
8 GTEx Skin Sun Exposed Lower leg RHOC 0.07 0.02 lasso 3 0.02 1.5e-02 -5.54 -5.4 5.9e-08 -0.16 0.54 0.02 FALSE
9 ROSMAP Brain Pre-frontal Cortex CAPZA1 0.05 0.06 lasso 3 0.06 1.1e-07 -5.54 -5.5 4.2e-08 -0.16 1.00 0.00 TRUE
10 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma CTTNBP2NL 0.04 0.00 blup 53 0.02 2.1e-03 -5.86 -6.5 8.5e-11 -0.27 0.03 0.19 FALSE
11 The Cancer Genome Atlas Liver Hepatocellular Carcinoma WNT2B 0.09 0.02 enet 13 0.04 5.1e-03 -5.74 -5.5 4.6e-08 -0.27 0.02 0.04 FALSE
12 The Cancer Genome Atlas Ovarian Serous Cystadenocarcinoma WNT2B 0.05 0.02 blup 46 0.05 4.7e-04 -5.59 -7.5 5.2e-14 -0.30 0.06 0.10 FALSE
13 The Cancer Genome Atlas Thyroid Carcinoma RHOC 0.04 0.03 enet 9 0.04 1.4e-04 -7.60 -8.4 5.4e-17 -0.30 0.01 0.97 TRUE