Best TWAS P=6.11e-08 · Best GWAS P=3.83e-10 conditioned to 0.000655
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Brain Cerebellar Hemisphere | HSD17B12 | 0.50 | 0.41 | enet | 33 | 0.29 | 3.0e-08 | 4.3 | -5.4 | 6.1e-08 | 0.72 | 0.62 | 0.38 | TRUE |
| 2 | GTEx | Breast Mammary Tissue | RP11-613D13.5 | 0.18 | 0.11 | lasso | 5 | 0.15 | 6.3e-08 | 3.9 | -5.1 | 2.9e-07 | 0.79 | 0.16 | 0.81 | FALSE |
| 3 | GTEx | Whole Blood | RP11-613D13.5 | 0.06 | 0.01 | lasso | 4 | 0.00 | 1.2e-01 | -5.4 | -5.4 | 7.2e-08 | 0.83 | 0.03 | 0.61 | FALSE |