[Hub]/) : Traits : Hypertension (Self-reported) :

chr16:69,337,091-71,292,172

Best TWAS P=2.44e-08 · Best GWAS P=1.58e-07 conditioned to 0.445

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adrenal Gland PDXDC2P 0.26 0.17 lasso 4 0.13 2.2e-05 4.8 -5.3 1.2e-07 -0.88 0.02 0.92 FALSE
2 GTEx Artery Aorta SF3B3 0.05 0.01 enet 9 0.01 6.4e-02 5.2 5.1 2.7e-07 0.95 0.02 0.88 FALSE
3 GTEx Brain Cerebellum PDPR 0.23 0.06 enet 20 0.11 3.7e-04 -4.3 -5.5 4.2e-08 -0.58 0.04 0.37 FALSE
4 GTEx Brain Cerebellum RP11-296I10.3 0.20 0.03 enet 12 0.14 8.8e-05 -4.4 -5.3 1.3e-07 -0.48 0.03 0.25 FALSE
5 GTEx Breast Mammary Tissue RP11-296I10.6 0.31 0.30 enet 17 0.30 7.1e-16 -4.3 -5.1 2.8e-07 -0.74 0.11 0.84 FALSE
6 GTEx Breast Mammary Tissue (Female) PDXDC2P 0.44 0.14 enet 16 0.16 1.9e-05 -5.0 -5.2 1.7e-07 -0.78 0.02 0.94 FALSE
7 GTEx Colon Sigmoid PDXDC2P 0.30 0.16 enet 13 0.14 8.8e-06 4.5 -5.5 3.1e-08 -0.82 0.04 0.93 FALSE
8 GTEx Colon Sigmoid RP11-296I10.6 0.32 0.33 enet 20 0.33 2.2e-12 -4.4 -5.2 1.5e-07 -0.79 0.08 0.88 FALSE
9 GTEx Esophagus Gastroesophageal Junction RP11-296I10.6 0.26 0.22 enet 15 0.20 7.9e-08 -4.4 -5.6 2.4e-08 -0.87 0.04 0.93 TRUE
10 GTEx Esophagus Muscularis SF3B3 0.05 0.02 enet 19 0.02 2.7e-02 -3.9 5.1 3.1e-07 0.67 0.09 0.40 FALSE
11 GTEx Stomach RP11-296I10.6 0.24 0.15 enet 14 0.16 4.5e-08 -4.4 -5.4 6.3e-08 -0.70 0.12 0.83 FALSE
12 GTEx Thyroid PDXDC2P 0.41 0.27 lasso 10 0.30 5.0e-23 4.8 -5.4 7.2e-08 -0.87 0.02 0.97 FALSE
13 The Cancer Genome Atlas Uterine Corpus Endometrial Carcinoma AARS 0.10 0.09 lasso 2 0.06 7.6e-03 4.8 5.4 6.4e-08 0.88 0.00 0.35 FALSE