Best TWAS P=5.44e-09 · Best GWAS P=1.43e-34 conditioned to 3.02e-25
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | METSIM | Adipose | SLC35F6 | 0.04 | 0.01 | blup | 362 | 0.02 | 1.1e-03 | 3.2 | 5.8 | 5.4e-09 | 0.49 | 0.11 | 0.39 | TRUE |
2 | ROSMAP | Brain Pre-frontal Cortex | KCNK3 | 0.24 | 0.15 | lasso | 3 | 0.15 | 6.5e-19 | 5.3 | -5.3 | 1.5e-07 | -0.35 | 1.00 | 0.00 | TRUE |