[Hub]/) : Traits : Hypertension (Self-reported) :

chr2:24,021,231-26,068,509

Best TWAS P=6.57e-12 · Best GWAS P=2.7e-10 conditioned to 0.0204

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Visceral Omentum NCOA1 0.11 0.02 enet 17 0.02 2.1e-02 -6.0 -6.9 6.6e-12 0.73 0.02 0.90 TRUE
2 GTEx Artery Aorta NCOA1 0.15 0.00 enet 15 0.01 1.4e-01 -4.2 -5.5 3.9e-08 0.60 0.03 0.57 FALSE
3 GTEx Esophagus Muscularis NCOA1 0.11 0.01 enet 9 0.01 5.8e-02 -6.3 -5.3 8.9e-08 0.83 0.01 0.85 FALSE
4 ROSMAP Brain Pre-frontal Cortex EFR3B 0.07 0.03 bslmm 348 0.03 3.5e-05 4.3 -6.3 2.6e-10 0.34 0.18 0.35 TRUE
5 YFS Blood CENPO 0.09 0.06 lasso 6 0.07 6.7e-21 -6.0 5.9 4.7e-09 -0.58 0.03 0.97 FALSE
6 The Cancer Genome Atlas Glioblastoma Multiforme ADCY3 0.36 0.14 enet 7 0.13 8.9e-05 -6.1 6.1 1.2e-09 -0.90 0.00 0.94 FALSE
7 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma ADCY3 0.08 0.03 enet 16 0.03 1.5e-04 -5.7 5.6 1.7e-08 -0.51 0.01 0.71 FALSE
8 The Cancer Genome Atlas Pancreatic Adenocarcinoma EFR3B 0.26 0.01 lasso 4 0.05 3.8e-03 -6.3 -6.0 1.6e-09 0.87 0.00 0.92 FALSE
9 The Cancer Genome Atlas Prostate Adenocarcinoma ADCY3 0.09 0.02 enet 11 0.04 3.2e-05 -6.1 6.2 7.6e-10 -0.79 0.00 0.99 FALSE