[Hub]/) : Traits : Hypertension (Self-reported) :

chr17:73,175,294-74,629,867

Best TWAS P=1.16e-08 · Best GWAS P=8.51e-09 conditioned to 0.257

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous FBF1 0.36 0.29 lasso 2 0.29 5.4e-24 -5.6 -5.7 1.5e-08 0.89 0.00 1.00 FALSE
2 GTEx Adipose Subcutaneous MRPL38 0.08 0.07 lasso 4 0.06 9.3e-06 -4.7 5.2 2.0e-07 -0.88 0.04 0.95 FALSE
3 GTEx Adipose Visceral Omentum FBF1 0.29 0.23 lasso 1 0.22 1.4e-11 -5.6 -5.6 2.1e-08 0.88 0.00 1.00 FALSE
4 GTEx Artery Aorta FBF1 0.32 0.27 lasso 2 0.26 2.2e-14 -5.6 -5.5 2.9e-08 0.89 0.00 1.00 FALSE
5 GTEx Artery Coronary FBF1 0.41 0.18 lasso 8 0.14 2.2e-05 -5.6 -5.1 2.8e-07 0.86 0.00 0.99 FALSE
6 GTEx Artery Tibial FBF1 0.36 0.33 enet 12 0.33 3.7e-26 -5.6 -5.5 4.1e-08 0.92 0.00 1.00 FALSE
7 GTEx Breast Mammary Tissue FBF1 0.15 0.20 lasso 3 0.19 6.9e-10 -5.6 -5.6 2.0e-08 0.89 0.00 1.00 FALSE
8 GTEx Colon Transverse FBF1 0.28 0.21 lasso 3 0.19 2.8e-09 -5.6 -5.6 2.1e-08 0.86 0.00 1.00 FALSE
9 GTEx Esophagus Gastroesophageal Junction FBF1 0.33 0.16 lasso 6 0.13 2.3e-05 -4.7 -5.2 2.5e-07 0.84 0.01 0.99 FALSE
10 GTEx Esophagus Muscularis FBF1 0.34 0.33 lasso 3 0.32 5.5e-20 -5.6 -5.7 1.4e-08 0.88 0.00 1.00 FALSE
11 GTEx Lung FBF1 0.20 0.18 lasso 1 0.17 2.6e-13 -5.6 -5.6 2.1e-08 0.88 0.00 1.00 FALSE
12 GTEx Pituitary FBF1 0.34 0.37 lasso 4 0.39 7.6e-11 -5.6 -5.4 7.6e-08 0.89 0.00 1.00 FALSE
13 GTEx Prostate FBF1 0.26 0.24 lasso 1 0.20 1.2e-05 -5.6 -5.6 2.1e-08 0.88 0.00 0.99 FALSE
14 GTEx Skin Sun Exposed Lower leg TRIM47 0.09 0.03 lasso 3 0.03 1.5e-03 -5.5 5.5 4.6e-08 -0.89 0.01 0.99 FALSE
15 GTEx Skin Sun Exposed Lower leg FBF1 0.22 0.23 lasso 1 0.21 3.0e-17 -5.6 -5.6 2.1e-08 0.88 0.00 1.00 FALSE
16 GTEx Stomach FBF1 0.28 0.17 enet 12 0.17 1.5e-08 -5.6 -5.7 1.2e-08 0.94 0.00 1.00 TRUE
17 GTEx Testis FBF1 0.37 0.38 lasso 2 0.38 8.4e-18 -5.6 -5.6 1.9e-08 0.88 0.00 1.00 FALSE
18 GTEx Thyroid TRIM65 0.19 0.11 lasso 2 0.09 3.5e-07 -5.6 -5.3 8.8e-08 0.85 0.01 0.99 FALSE
19 GTEx Thyroid FBF1 0.24 0.23 lasso 2 0.23 8.0e-18 -5.6 -5.4 8.6e-08 0.87 0.00 1.00 FALSE