[Hub]/) : Traits : Deep venous thrombosis (DVT) (self-reported) :

chr4:186,328,499-187,829,016

Best TWAS P=3.31e-15 · Best GWAS P=1.92e-23 conditioned to 0.000371

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Brain Caudate basal ganglia CYP4V2 0.37 0.17 enet 24 0.19 4.0e-06 -5.95 -7.4 1.8e-13 -0.41 0.21 0.33 FALSE
2 GTEx Brain Cerebellum CYP4V2 0.44 0.31 lasso 3 0.31 7.4e-10 -5.95 -5.9 4.1e-09 -0.28 0.88 0.03 FALSE
3 GTEx Colon Transverse CYP4V2 0.29 0.23 lasso 6 0.22 5.8e-11 -5.95 -5.5 3.4e-08 -0.31 1.00 0.00 TRUE
4 GTEx Heart Atrial Appendage FAM149A 0.36 0.03 enet 22 0.02 4.3e-02 0.19 5.3 1.1e-07 0.17 0.16 0.04 FALSE
5 GTEx Nerve Tibial CYP4V2 0.22 0.05 lasso 6 0.09 1.3e-06 -1.75 -6.9 5.6e-12 -0.40 0.91 0.06 FALSE
6 GTEx Pancreas CYP4V2 0.31 0.27 enet 15 0.28 2.0e-12 -5.75 -5.1 3.0e-07 -0.23 1.00 0.00 TRUE
7 GTEx Pituitary CYP4V2 0.61 0.34 lasso 6 0.44 2.6e-12 -3.23 -5.3 1.4e-07 -0.28 0.98 0.00 FALSE
8 GTEx Spleen CYP4V2 0.55 0.30 lasso 6 0.25 5.2e-07 -5.95 -6.1 1.0e-09 -0.31 0.54 0.03 FALSE
9 GTEx Thyroid CYP4V2 0.54 0.29 lasso 6 0.44 1.2e-36 -5.95 -6.1 1.3e-09 -0.35 1.00 0.00 FALSE
10 The Cancer Genome Atlas Lung Squamous Cell Carcinoma F11 0.05 0.03 enet 9 0.04 1.8e-05 -5.55 -7.9 3.3e-15 -0.56 0.07 0.90 TRUE