[Hub]/) : Traits : Asthma (self-reported) :

chr17:46,581,184-48,139,500

Best TWAS P=2.39e-14 · Best GWAS P=5.92e-16 conditioned to 0.00299

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 METSIM Adipose ZNF652 0.05 0.03 lasso 8 0.05 6.2e-08 -3.5 -5.1 2.8e-07 -0.69 0.68 0.32 FALSE
2 YFS Blood GNGT2 0.13 0.13 lasso 5 0.12 1.1e-38 4.8 5.2 2.1e-07 0.76 1.00 0.00 FALSE
3 The Cancer Genome Atlas Colon Adenocarcinoma ZNF652 0.09 0.01 enet 12 0.05 5.5e-04 6.7 -5.6 2.2e-08 -0.55 0.02 0.40 FALSE
4 The Cancer Genome Atlas Glioblastoma Multiforme GNGT2 0.22 0.00 blup 47 0.00 3.1e-01 4.8 5.4 6.7e-08 0.76 0.01 0.12 FALSE
5 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma GNGT2 0.09 0.07 blup 48 0.06 2.7e-07 4.8 5.1 2.9e-07 0.72 0.16 0.83 FALSE
6 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma ZNF652 0.03 0.03 enet 5 0.03 2.6e-04 6.7 -7.1 1.5e-12 -0.90 0.02 0.96 FALSE
7 The Cancer Genome Atlas Brain Lower Grade Glioma ZNF652 0.06 0.03 lasso 4 0.02 1.6e-03 6.8 -6.2 7.3e-10 -0.76 0.18 0.61 FALSE
8 The Cancer Genome Atlas Lung Adenocarcinoma ZNF652 0.05 0.02 blup 55 0.02 2.5e-03 8.1 -7.6 2.4e-14 -0.87 0.01 0.98 TRUE