Best TWAS P=3.46e-08 · Best GWAS P=1.3e-07 conditioned to 1
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Esophagus Gastroesophageal Junction | PMS2P5 | 0.23 | 0.19 | lasso | 2 | 0.18 | 5.4e-07 | 5.3 | -5.5 | 3.5e-08 | -0.97 | 0 | 1.00 | TRUE |
2 | GTEx | Heart Atrial Appendage | PMS2P5 | 0.12 | 0.03 | lasso | 5 | 0.07 | 3.8e-04 | 5.3 | -5.4 | 7.4e-08 | -0.92 | 0 | 0.84 | FALSE |
3 | GTEx | Testis | PMS2P5 | 0.22 | 0.13 | lasso | 2 | 0.13 | 3.1e-06 | 5.3 | -5.3 | 9.8e-08 | -0.99 | 0 | 0.99 | FALSE |