Best TWAS P=2.24e-09 · Best GWAS P=3.5e-10 conditioned to 7.04e-07
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Nerve Tibial | PQLC2 | 0.07 | 0.08 | lasso | 3 | 0.06 | 6.6e-05 | 5.6 | -5.6 | 2.0e-08 | -0.13 | 0.04 | 0.95 | FALSE |
| 2 | GTEx | Thyroid | CAPZB | 0.22 | 0.06 | lasso | 8 | 0.15 | 1.1e-11 | -2.9 | 6.0 | 2.2e-09 | 0.25 | 0.89 | 0.10 | TRUE |
| 3 | The Cancer Genome Atlas | Thyroid Carcinoma | CAPZB | 0.08 | 0.06 | blup | 160 | 0.07 | 1.2e-07 | -3.1 | 5.7 | 1.5e-08 | 0.27 | 0.97 | 0.02 | FALSE |