Best TWAS P=1.85e-07 · Best GWAS P=6.01e-07 conditioned to 0.222
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Brain Cortex | HMGCL | 0.22 | 0.09 | enet | 12 | 0.12 | 3.2e-04 | 4.5 | 5.2 | 1.9e-07 | 0.83 | 0.02 | 0.83 | TRUE |
2 | The Cancer Genome Atlas | Testicular Germ Cell Tumors | FUCA1 | 0.20 | 0.15 | blup | 35 | 0.14 | 1.5e-05 | 4.5 | 5.2 | 2.1e-07 | 0.56 | 0.00 | 0.92 | FALSE |