[Hub]/) : Traits : Hypothyroidism/myxoedema (self-reported) :

chr1:23,431,777-24,861,704

Best TWAS P=1.85e-07 · Best GWAS P=6.01e-07 conditioned to 0.222

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Brain Cortex HMGCL 0.22 0.09 enet 12 0.12 3.2e-04 4.5 5.2 1.9e-07 0.83 0.02 0.83 TRUE
2 The Cancer Genome Atlas Testicular Germ Cell Tumors FUCA1 0.20 0.15 blup 35 0.14 1.5e-05 4.5 5.2 2.1e-07 0.56 0.00 0.92 FALSE