Best TWAS P=5.63e-11 · Best GWAS P=2.54e-12 conditioned to 0.000111
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | CommonMind | Brain Pre-frontal Cortex | TG | 0.15 | 0.08 | bslmm | 886 | 0.09 | 4.0e-11 | 6.9 | 6.0 | 1.5e-09 | 0.67 | 0.02 | 0.98 | FALSE |
| 2 | METSIM | Adipose | TG | 0.22 | 0.26 | enet | 27 | 0.27 | 5.8e-41 | -5.3 | 5.5 | 2.9e-08 | 0.61 | 1.00 | 0.00 | FALSE |
| 3 | ROSMAP | Brain Pre-frontal Cortex | TG | 0.07 | 0.01 | enet | 26 | 0.04 | 2.0e-06 | 6.8 | 5.3 | 9.4e-08 | 0.66 | 0.04 | 0.96 | FALSE |
| 4 | YFS | Blood | PHF20L1 | 0.04 | 0.00 | lasso | 10 | 0.01 | 3.2e-05 | -5.2 | 5.3 | 1.2e-07 | 0.55 | 0.95 | 0.05 | FALSE |
| 5 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | PHF20L1 | 0.04 | 0.02 | lasso | 2 | 0.01 | 4.2e-02 | -5.2 | 5.2 | 2.5e-07 | 0.55 | 0.02 | 0.68 | FALSE |
| 6 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | TG | 0.03 | 0.00 | lasso | 8 | 0.01 | 1.6e-02 | -5.3 | 6.2 | 5.8e-10 | 0.69 | 0.10 | 0.67 | FALSE |
| 7 | The Cancer Genome Atlas | Lung Adenocarcinoma | TG | 0.04 | 0.00 | enet | 13 | 0.00 | 8.8e-02 | -5.3 | 6.5 | 5.6e-11 | 0.59 | 0.10 | 0.62 | TRUE |