[Hub]/) : Traits : Hypothyroidism/myxoedema (self-reported) :

chr10:5,027,660-6,677,767

Best TWAS P=1.8e-15 · Best GWAS P=2.95e-15 conditioned to 0.0625

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Nerve Tibial FBXO18 0.1 0.00 lasso 5 0.00 0.5450 -7.2 -5.7 1.4e-08 0.46 0.05 0.69 TRUE
2 GTEx Skin Sun Exposed Lower leg FAM208B 0.1 0.03 lasso 4 0.03 0.0014 -6.7 -8.0 1.8e-15 0.72 0.06 0.69 TRUE