Best TWAS P=1.8e-15 · Best GWAS P=2.95e-15 conditioned to 0.0625
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Nerve Tibial | FBXO18 | 0.1 | 0.00 | lasso | 5 | 0.00 | 0.5450 | -7.2 | -5.7 | 1.4e-08 | 0.46 | 0.05 | 0.69 | TRUE |
2 | GTEx | Skin Sun Exposed Lower leg | FAM208B | 0.1 | 0.03 | lasso | 4 | 0.03 | 0.0014 | -6.7 | -8.0 | 1.8e-15 | 0.72 | 0.06 | 0.69 | TRUE |