TWAS hub - FBXO18

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Adipose Subcutaneous	0.0990	0.0370	1.7e-03	0.015	NA	-0.002	NA	0.013	1.9e-02	NA	5.3e-01	NA	2.9e-02
2	GTEx	Artery Tibial	0.1278	0.0454	2.1e-03	0.011	NA	0.020	NA	0.008	4.3e-02	NA	9.1e-03	NA	7.8e-02
3	GTEx	Cells Transformed fibroblasts	0.0900	0.0350	6.1e-03	-0.004	NA	0.010	NA	0.004	9.3e-01	NA	5.3e-02	NA	1.5e-01
4	GTEx	Nerve Tibial	0.1000	0.0359	2.8e-03	-0.003	NA	-0.004	NA	-0.002	7.3e-01	NA	8.5e-01	NA	5.4e-01
5	GTEx	Skin Not Sun Exposed Suprapubic	0.1500	0.0610	5.5e-03	0.065	NA	0.022	NA	0.049	2.0e-04	NA	2.3e-02	NA	1.1e-03
6	GTEx	Skin Sun Exposed Lower leg	0.2350	0.0560	9.0e-07	0.067	NA	0.092	NA	0.121	3.4e-06	NA	4.5e-08	NA	3.1e-10
7	GTEx	Thyroid	0.1880	0.0480	3.0e-05	0.046	NA	0.061	NA	0.081	1.8e-04	NA	2.0e-05	NA	9.3e-07
8	GTEx	Whole Blood	0.1000	0.0390	3.8e-03	0.018	NA	0.053	NA	0.023	8.5e-03	NA	1.2e-05	NA	2.9e-03
9	METSIM	Adipose	0.1135	0.0302	2.0e-06	0.056	0.040	0.041	0.043	0.050	8.7e-09	1.2e-06	7.1e-07	4.6e-07	5.7e-08
10	NTR	Blood	0.0274	0.0110	5.8e-03	0.000	0.002	0.001	0.005	0.004	3.0e-01	4.7e-02	9.5e-02	8.4e-03	1.3e-02
11	ROSMAP	Brain Pre-frontal Cortex	0.0528	0.0241	2.0e-02	0.039	0.007	0.019	0.032	0.034	8.8e-06	3.2e-02	1.5e-03	4.9e-05	3.2e-05

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9	10	11
Illnesses of father: Heart disease	4.5	6.2	10.8	3.2	2.1	1.7	3.3	3.1	2.5	2.4	2.9	2.3	2.2	0.5
Miserableness	3.5	6.0	13.5	3.1	1.2	1.8	1.9	3.7	3.0	2.6	1.9	2.8	2.3	1.7
Ever smoked	3.5	6.2	11.7	2.9	1.3	2.7	0.7	3.2	3.1	2.2	3.2	1.8	3.4	1.0
Bipolar Disorder (2018)	3.0	4.7	8.2	2.5	0.0	0.7	1.6	2.2	1.7	2.9	2.0	2.9	2.6	2.7
Guilty feelings	2.8	4.2	11.3	1.5	1.1	0.9	2.1	2.2	1.2	3.0	1.4	2.4	1.7	3.4
Average weekly fortified wine intake	2.7	3.2	9.2	-3.0	-0.0	-1.2	-0.8	-2.5	-2.7	-1.3	-2.0	-2.0	-0.2	-0.8
Mood swings	2.7	4.8	8.5	2.4	2.2	2.5	1.6	2.9	2.4	2.6	1.3	1.5	2.1	2.1
Medication: Aspirin	2.7	3.5	11.5	1.1	1.5	0.9	0.6	2.1	0.6	3.4	1.2	1.7	1.4	3.3
Wears glasses or contact lenses	2.7	3.1	6.2	-2.1	-2.5	-1.2	-1.7	-2.2	-1.9	-1.7	-2.0	-1.8	0.4	-0.7
Alzheimer’s Disease (including proxy)	2.6	3.8	13.8	-2.2	-1.7	-0.8	-3.7	-2.8	-1.4	-0.0	-2.6	-1.3	-1.1	0.5
Lupus	2.5	3.8	9.3	2.4	2.0	2.9	0.4	2.0	3.0	0.7	1.7	2.0	1.4	-0.5
Pack years adult smoking proportion	2.5	3.8	8.7	0.8	3.0	0.7	2.9	2.3	0.3	2.6	1.7	0.8	1.2	2.5
Breast Cancer	2.4	5.8	13.7	3.7	1.7	0.8	1.8	2.5	3.3	1.7	2.8	3.5	1.9	-0.3
Emphysema/chronic bronchitis	2.4	2.7	6.9	-1.6	-0.3	-0.9	-2.6	-1.6	-1.4	-2.4	-2.1	-1.4	-0.5	-1.6
Illness, injury, bereavement, stress in last 2 years	2.4	3.0	5.0	1.4	0.2	1.6	2.1	2.2	2.1	2.1	1.2	1.1	1.9	1.9
Commuting to job workplace: Cycle	2.4	2.9	4.7	1.5	2.2	1.1	1.8	1.8	1.5	1.5	2.1	2.0	1.1	1.8
Hypothyroidism (self reported)	2.3	5.4	39.6	-0.8	-2.1	0.7	-6.3	-2.4	-0.7	-1.1	-0.6	0.1	2.4	-0.3
Financial situation satisfaction	2.3	2.9	6.6	-1.5	-1.9	-2.2	-0.9	-1.9	-2.1	-1.4	-1.5	-0.5	-2.6	-0.8
Supplements: Calcium	2.3	2.6	5.5	-2.1	-0.9	-0.4	-2.3	-1.7	-1.9	-2.0	-0.3	-1.9	-1.7	-0.8
Pack years of smoking	2.3	3.3	7.3	0.6	2.7	0.6	2.7	2.2	0.1	2.5	1.6	0.8	1.1	2.5
Qualifications: CSEs or equivalent	2.2	2.9	7.2	-1.6	-1.7	-1.8	-0.7	-1.3	-0.1	-2.2	-1.6	-1.8	-2.7	-1.9
Hypothyroidism/myxoedema (self-reported)	2.2	4.3	32.1	-0.7	-2.4	0.2	-5.7	-2.0	-0.1	-0.7	-0.9	-0.0	1.8	-0.2
Ovarian Cancer	2.1	2.7	9.6	1.9	1.6	-0.2	1.7	1.8	3.1	1.3	0.1	1.0	2.2	0.9
Smoking Status	2.1	4.9	12.0	2.9	1.8	2.0	1.1	2.4	3.5	1.9	2.7	2.2	1.8	0.7
Sensitivity / hurt feelings	2.1	3.6	8.5	2.2	1.8	2.2	2.5	2.4	1.6	1.2	1.4	2.9	0.6	0.5
Frequency of depressed mood in last 2 weeks	2.1	3.0	5.1	1.6	0.9	0.5	1.5	1.6	1.7	2.3	1.6	2.1	2.1	2.2
Medication: Levothyroxine sodium	2.1	3.6	22.5	-0.8	-2.6	0.5	-4.7	-1.6	0.2	0.4	-1.4	0.0	2.0	1.1
Past tobacco smoking	2.1	3.9	7.8	-2.3	-0.3	-2.1	-1.4	-2.6	-2.8	-1.9	-2.3	-1.2	-2.4	-0.5
Tense / ‘highly strung’	2.1	3.4	8.1	1.1	1.1	1.3	1.9	1.6	1.1	2.8	1.6	2.1	1.7	2.9
Medication: Metformin	2.0	2.8	6.8	2.1	0.1	2.2	0.9	2.0	2.6	2.0	-0.3	1.4	1.9	0.3
Serious illness, injury or assault of a close relative in last 2 years	2.0	2.3	5.2	-1.3	-0.1	-0.2	-2.3	-1.4	-2.1	-1.8	1.1	-1.5	-1.8	-1.4
Average weekly red wine intake	2.0	2.9	7.1	1.2	0.5	2.2	2.7	2.5	1.3	1.8	1.2	1.6	-0.3	1.9
Basal cell carcinoma (self-reported)	2.0	2.4	4.8	1.3	2.0	0.0	1.4	2.1	1.6	2.1	2.2	1.1	0.2	1.4
Alzheimer’s Disease (in mother)	1.9	2.2	9.5	-1.6	-1.8	-1.5	-3.1	-1.8	-1.3	0.3	-1.0	-0.7	0.1	0.3
Reaction Time	1.9	3.7	8.0	-2.3	-0.3	-0.5	-2.7	-2.8	-2.8	-1.7	-1.0	-2.2	-1.3	-1.1
Respiratory disease	1.9	4.3	26.6	0.3	-2.2	-1.8	-5.2	-1.1	-0.2	-2.0	-2.1	-0.0	-0.1	-1.9
Hayfever, allergic rhinitis or eczema	1.9	4.1	30.4	0.3	-2.2	-1.0	-5.5	0.2	-1.7	-2.2	0.4	0.1	-0.4	-0.8
Reason for reducing amount of alcohol drunk: Health precaution	1.9	2.3	10.9	0.5	0.3	0.6	1.2	1.1	0.9	2.5	0.9	1.4	1.0	3.3
Angina (self-reported)	1.8	2.3	3.9	2.0	0.4	1.5	1.8	1.5	1.8	1.9	1.3	2.0	1.2	0.6
Leg pain on walking	1.8	2.2	4.5	-1.0	-0.4	-1.3	-1.4	-1.6	-0.9	-1.8	-2.1	-0.7	-2.1	-1.9
Primary Biliary Cirrhosis	1.7	2.4	6.8	2.2	1.2	0.7	2.2	2.6	0.8	1.4	0.0	1.4	1.4	1.0
Medication: Atenolol	1.7	2.1	4.7	1.9	0.7	1.9	1.1	0.9	1.3	2.0	0.5	2.2	1.3	0.9
Allergy	1.7	3.8	32.7	-0.9	1.9	0.9	5.7	-0.8	0.6	1.5	0.3	-0.3	0.4	0.4
Impedance of arm (left)	1.7	7.8	15.5	2.9	3.0	1.2	2.4	3.2	2.7	2.8	3.9	3.2	2.6	2.0
Medication: Aspirin	1.7	2.3	9.5	0.5	0.9	0.6	0.1	1.6	0.2	3.0	0.3	1.2	1.0	3.1
Asthma (self-reported)	1.7	3.4	16.3	0.8	-2.3	-1.3	-4.0	-0.6	0.3	-2.2	-2.1	-0.1	-0.4	-1.8
Impedance of whole body	1.7	8.9	18.2	3.0	3.6	0.9	3.2	3.6	2.8	2.3	4.3	3.4	2.6	1.7
Neuroticism (Nagel 2018)	1.6	3.8	8.0	1.3	2.0	2.0	2.5	2.8	1.6	2.1	1.4	1.8	1.2	2.1
Crohns Disease (2017)	1.6	3.5	8.2	2.9	1.0	2.0	1.3	2.5	2.2	-0.1	1.7	2.7	0.7	-1.1
Allergy or Eczema	1.6	4.3	35.6	0.2	-2.1	-0.6	-6.0	0.5	-1.6	-1.8	0.4	0.4	0.2	-0.4
Medication for hormone replacement therapy	1.6	1.8	6.1	1.0	0.2	-0.1	-0.4	1.1	0.5	2.3	0.3	1.5	2.5	1.7
Medication: Atorvastatin	1.6	1.9	5.7	1.5	0.5	-0.0	0.7	1.0	0.4	2.4	0.4	1.8	2.3	1.6
Major Depression (MDD)	1.5	1.8	4.6	0.6	2.1	1.4	0.2	1.0	0.8	1.7	2.1	0.7	1.5	1.3
Neuroticism (2016)	1.5	2.1	5.3	1.3	1.8	1.6	2.3	2.0	1.6	1.2	1.1	0.9	0.3	0.7
Alcohol intake versus 10 years previously	1.5	2.2	7.0	1.8	2.7	-1.0	1.9	1.2	1.9	-0.1	-0.3	1.7	0.1	-1.2
Asthma	1.5	3.0	15.1	0.9	-2.1	-1.5	-3.9	-0.2	0.3	-1.9	-2.1	0.2	-0.2	-1.6
Medication: Ibuprofen (e.g. Nurofen)	1.5	1.9	4.4	-2.0	-2.1	-1.3	-0.4	-1.3	-2.1	0.4	-0.1	-1.3	0.5	1.8
Risk taking	1.5	2.2	4.4	1.8	0.7	1.4	2.1	2.0	2.1	1.6	0.2	1.0	1.2	0.8
Heart disease (siblings)	1.5	1.8	5.2	1.4	1.6	2.3	0.9	1.0	0.8	0.3	2.1	1.8	0.5	0.6
Depression (Nagel 2018)	1.4	2.1	5.9	1.0	1.1	1.0	0.6	1.4	1.4	2.2	-0.2	1.2	1.8	2.4
Mean Putamen Volume	1.4	1.6	6.3	1.0	1.1	0.6	1.3	1.3	1.3	1.3	2.5	0.6	-0.4	1.2
Friendships satisfaction	1.4	1.8	3.7	-1.5	-1.2	-1.8	-1.2	-1.9	-1.4	0.5	-1.0	-1.2	-1.3	1.1
Mouth/teeth dental problems: Mouth ulcers	1.4	2.3	11.4	1.4	1.5	-0.2	3.4	2.1	1.0	0.4	0.6	1.9	-0.2	0.4
Irritability	1.4	2.4	6.7	0.7	0.6	0.6	1.1	1.8	0.9	2.3	2.4	1.1	1.1	2.6
HbA1C	1.3	1.4	5.6	-1.1	-0.5	-2.4	-1.1	-0.6	-1.7	-0.3	-0.2	-0.9	-1.5	0.8
Rheumatoid Arthritis	1.3	1.8	13.6	-0.7	-3.7	-1.2	-0.7	-0.7	0.3	0.6	-0.9	-0.3	0.1	1.1
Angina	1.3	1.7	3.3	1.6	0.3	1.4	1.5	1.2	1.4	1.8	1.2	1.6	0.9	0.7
Impedance of arm (right)	1.3	5.9	14.4	2.3	2.5	0.8	2.4	2.7	2.2	2.3	3.8	2.7	2.2	1.8
Breastfed as a baby	1.3	1.6	3.5	-1.7	-0.6	-1.9	-0.3	-1.6	-0.7	-1.2	-0.7	-1.8	-1.4	-1.1
Medication: Allopurinol	1.3	1.7	5.6	-1.0	0.7	-1.1	-2.4	-1.8	-0.5	-1.3	-0.8	-1.4	-0.2	-1.6
Breast cancer (self-reported)	1.3	1.6	3.3	-1.3	-1.0	-1.4	-1.3	-1.8	-0.8	-1.6	0.1	-1.1	-0.9	-1.5
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.3	2.8	7.8	-2.2	-0.9	0.6	-0.9	-2.8	-2.4	-0.7	-1.9	-1.9	-1.3	-0.2
Mother’s age at death	1.3	1.7	3.7	-1.8	-0.6	0.1	-0.9	-1.9	-1.8	-0.7	-1.1	-1.9	-1.3	0.4
Alcohol drinker status: Never	1.3	1.6	3.4	-1.3	-0.7	-0.4	-1.3	-1.9	-0.9	-1.2	-1.8	-1.7	-0.8	-0.6
Lung FEV1/FVC ratio	1.2	5.9	15.1	0.9	2.0	2.1	2.3	1.4	1.1	3.4	2.2	2.3	3.2	3.9
Diabetes (father)	1.2	1.5	4.0	1.6	1.2	-0.3	0.0	2.0	1.5	0.9	1.7	1.2	0.7	0.0
Impedance of leg (left)	1.2	5.8	15.5	2.1	2.8	0.7	3.1	3.1	2.0	1.1	3.9	2.7	1.7	1.0
Frequency of tenseness / restlessness in last 2 weeks	1.2	1.9	3.2	0.9	0.7	1.7	1.3	0.8	1.4	1.6	1.1	1.8	1.5	1.7
Hayfever/allergic rhinitis (self-reported)	1.2	1.6	10.6	-0.8	-0.9	-0.9	-3.3	-0.3	-0.8	-1.0	-1.5	-0.4	0.5	-0.2
High blood pressure (siblings)	1.2	1.7	3.7	-1.1	-1.6	-1.9	0.3	-1.6	-1.9	-1.3	-1.4	-0.7	-0.3	-0.6
Comparative body size at age 10	1.2	3.3	13.2	-1.4	-0.5	-2.1	-2.6	-1.6	-1.2	-1.5	-3.6	-1.1	-1.1	-1.1
Medication: Omeprazole	1.2	1.4	4.0	1.8	-0.9	0.2	2.0	1.4	0.4	0.4	1.7	0.8	0.5	-1.3
Family relationship satisfaction	1.2	1.4	4.9	1.7	0.2	-2.2	-1.7	-0.0	0.7	0.2	-0.1	1.9	-0.5	-0.9
Qualifications: nursing, teaching	1.2	1.8	3.1	1.5	1.0	0.1	0.5	1.6	1.5	1.8	1.7	1.6	1.5	1.0
Medication for cholesterol	1.2	1.7	7.6	-0.6	-0.6	-0.4	-0.3	-1.0	-0.2	-2.8	0.5	0.1	-2.2	-2.1
Blood Eosinophil Count	1.1	8.4	37.7	-0.9	-5.4	0.6	-6.1	-1.6	-1.5	-0.5	-3.1	-2.5	1.7	0.7
Impedance of leg (right)	1.1	5.4	13.8	2.2	2.5	1.2	3.0	2.7	2.0	1.0	3.7	2.7	1.8	1.2
Had other major operations	1.1	1.4	2.9	-1.3	-1.2	-0.6	-1.7	-1.4	-1.4	0.9	-0.5	-1.3	0.8	1.1
Pain all over the body in last month	1.1	1.2	3.9	-0.7	-0.8	-0.2	-1.8	-2.0	-1.3	-0.9	-1.1	-0.9	0.1	0.3
Father’s age at death	1.1	1.5	3.6	1.8	0.8	1.9	0.7	0.7	1.3	-1.0	0.3	1.4	-0.2	-1.9
Headache pain in last month	1.1	1.8	5.9	0.1	0.9	-0.0	1.3	1.2	1.2	2.1	1.5	0.1	1.5	2.4
Medication: Ventolin 100micrograms inhaler	1.1	1.4	3.9	1.1	-1.4	-1.1	-2.0	0.0	0.1	-1.9	0.5	0.3	0.2	-1.6
Number of children fathered	1.1	1.2	5.4	-0.9	-1.4	0.2	-0.2	-1.3	-1.5	0.6	-2.3	-0.4	-0.2	1.0
Qualifications: College or University degree	1.1	3.6	10.3	1.3	0.7	1.1	1.7	2.7	1.3	2.3	3.2	1.2	1.4	2.3
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.1	1.3	3.8	-0.9	-1.0	-0.1	0.1	-0.8	-2.0	-1.1	-1.6	-1.3	-0.9	-1.4
Loneliness, isolation	1.1	1.5	4.2	-1.2	-1.7	0.1	-0.8	-1.6	-2.0	-1.6	-1.1	-0.3	-0.9	-0.6
Ever had stillbirth, spontaneous miscarriage or termination	1.1	1.1	3.2	1.3	1.3	1.8	-1.1	1.2	0.7	1.1	0.1	0.8	1.1	0.3
Ever taken oral contraceptive pill	1.1	1.2	4.4	1.1	-0.5	1.0	-0.9	-0.3	1.2	-1.2	-1.4	0.4	-1.0	-2.1
Supplements: Zinc	1.0	1.0	2.3	-0.8	0.1	-1.1	-1.4	-1.3	-1.5	-1.0	0.9	-0.8	-0.8	0.4
Had menopause	1.0	1.2	3.9	1.0	-1.1	-0.4	0.4	0.2	-0.2	0.8	1.3	2.0	1.9	1.0
Ever highly irritable/argumentative for 2 days	1.0	1.2	4.0	2.0	1.6	-0.2	1.2	0.5	1.6	0.8	0.5	0.8	0.0	-0.4
Chronic bronchitis/emphysema (mother)	1.0	1.2	2.4	1.5	0.3	1.4	1.5	1.3	1.4	0.5	1.4	0.6	0.4	0.2
Seen a psychiatrist for nerves, anxiety, tension or depression	1.0	1.2	7.0	1.3	0.4	2.6	0.7	0.1	0.1	1.0	-0.6	1.4	1.0	0.2
Wheeze or whistling in the chest in last year	1.0	1.8	6.6	-0.1	-1.9	-1.1	-2.6	-0.7	-0.6	-1.2	-2.1	0.1	-0.6	-1.0
Shortness of breath walking on level ground	1.0	1.2	3.4	-0.9	-0.7	-1.9	-1.6	-0.7	-0.6	-0.7	-1.2	-1.5	-0.3	-0.8
Smoking status: Previous	1.0	1.4	3.6	1.2	-0.6	1.5	0.9	1.6	1.9	1.0	0.8	0.2	1.7	-0.2
Commuting to job workplace: Public transport	1.0	1.2	3.0	1.7	0.2	1.7	0.8	0.6	1.4	0.8	0.6	1.1	1.4	0.5
Unable to work because of sickness or disability	1.0	1.3	3.6	-0.4	0.1	0.4	-0.6	-1.1	-0.6	-1.6	-1.5	-1.5	-1.1	-1.9
Depressed Affect (Nagel 2018)	0.9	2.0	5.1	0.8	1.5	1.6	1.2	2.3	1.1	1.8	0.1	0.4	1.3	1.9
Verbal and Numeric Reasoning (VNR)	0.9	2.1	5.8	-1.6	-2.4	-0.6	-1.9	-1.3	-1.7	-0.8	1.5	-0.7	-1.5	-0.2
Lung FVC	0.9	4.3	11.3	-2.8	-1.6	-1.2	-0.5	-1.9	-3.0	-1.6	-1.6	-2.4	-3.4	-0.9
Average weekly spirits intake	0.9	1.1	2.4	-1.5	-0.1	-0.8	-0.7	-1.3	-1.6	-1.2	0.1	-0.9	-1.4	-0.5
Hearing difficulty/problems: Yes	0.9	1.4	2.7	-1.5	-0.8	-1.6	-0.4	-1.6	-1.2	-1.5	-0.7	-0.8	-1.0	-1.2
Medication: Co-codamol	0.9	1.0	3.3	-0.7	-0.8	-0.7	-0.9	-1.8	-1.1	0.2	-1.1	-1.3	-0.8	0.3
Severe depression (siblings)	0.9	1.0	3.4	1.0	0.3	0.4	0.8	0.9	-0.2	1.8	1.3	1.4	0.8	0.9
Diverticular disease/diverticulitis (self-reported)	0.9	1.1	4.0	1.6	1.2	0.4	0.7	0.6	1.0	1.3	0.5	2.0	-0.3	0.2
Neuroticism score	0.9	1.9	4.1	1.0	0.4	1.1	1.5	1.9	0.7	1.4	1.0	2.0	1.3	1.8
Mouth/teeth dental problems: Dentures	0.9	1.5	3.8	-1.8	-2.0	-0.6	-0.6	-1.4	-1.8	-1.0	-0.9	-0.9	0.3	-0.4
Birth weight of first child	0.9	1.6	7.4	1.2	0.9	0.5	-0.3	-0.5	0.4	-1.1	1.6	0.7	-1.5	-2.7
Pulse wave reflection index	0.9	1.1	4.3	0.9	1.7	2.1	-0.4	0.1	1.7	-0.5	-0.1	-0.1	0.2	-1.1
Medication: Ibuprofen	0.9	1.1	3.8	-1.5	-1.2	-0.5	0.0	-0.7	-1.6	0.5	0.3	-1.1	0.6	1.9
Illnesses of siblings: Diabetes	0.9	1.2	5.9	-0.1	-1.7	-0.5	-2.4	-1.2	-0.1	-0.3	-0.4	0.3	1.3	-0.4
Long-standing illness, disability or infirmity	0.9	1.4	9.6	0.9	-0.4	-0.3	-3.1	-1.0	-1.0	-0.0	-1.2	1.0	0.3	-0.5
Mineral and other dietary supplements	0.9	1.1	3.0	-0.4	-1.7	1.6	-1.7	-1.1	0.2	-0.8	-1.1	-0.7	-0.6	-0.6
Pain type(s) experienced in last month: Hip pain	0.9	1.1	3.8	1.0	0.9	1.1	0.8	-0.0	1.2	-0.4	-1.7	0.4	0.0	-1.9
Supplements: Fish oil (including cod liver oil)	0.9	1.2	2.4	0.8	1.5	-1.0	1.5	1.2	0.1	0.2	1.4	1.5	0.3	-1.0
Bipolar Disorder or Schizophrenia	0.8	2.0	4.3	1.8	-0.0	0.1	0.3	1.9	1.5	1.8	2.0	1.2	0.5	2.1
Irritable Bowel Disease (IBD)	0.8	1.9	4.6	2.0	0.2	1.3	1.5	2.0	1.5	0.1	1.3	2.1	0.8	0.0
Townsend deprivation index at recruitment	0.8	1.2	6.9	1.2	-0.2	-0.2	1.0	-0.0	0.4	-1.2	-1.2	0.5	-0.4	-2.6
Fed-up feelings	0.8	1.4	2.9	1.2	1.0	1.1	1.3	1.7	1.5	1.3	0.1	0.9	1.1	1.1
Frequency of unenthusiasm / disinterest in last 2 weeks	0.8	1.1	1.8	1.3	0.9	0.8	1.0	0.9	1.3	1.3	-1.2	0.9	0.8	0.7
Medication for cholesterol, blood pressure or diabetes	0.8	1.4	6.7	-0.9	-1.2	-2.6	-0.2	-0.5	-0.6	-0.5	-1.2	-1.7	-0.9	0.1
Worry too long after embarrassment	0.8	1.3	2.9	0.8	0.9	1.6	1.2	1.2	0.5	0.8	0.7	1.7	1.2	1.2
Tinnitus: Yes, now most or all of the time	0.8	0.9	2.5	0.9	0.4	-1.6	0.5	0.1	-0.1	-0.8	1.6	1.0	-0.7	-1.2
Cholesterol lowering medication	0.8	1.1	3.5	1.1	0.2	1.9	0.8	1.1	0.4	1.6	-0.9	0.3	1.2	0.7
Prostate Cancer	0.7	0.9	3.8	-0.9	-0.7	-0.8	-1.4	-0.5	-1.1	-0.1	-0.6	-1.9	0.7	0.3
Type 2 Diabetes (T2D) (2018)	0.7	1.3	2.9	1.5	0.4	1.5	0.4	1.3	1.2	1.5	0.6	1.7	0.5	0.7
Neuroticism	0.7	1.6	4.7	0.7	0.6	0.3	1.5	2.2	1.1	1.5	0.8	1.3	0.9	1.7
Eye problems/disorders: Diabetes related eye disease	0.7	0.7	2.7	-0.8	-0.6	1.0	-0.2	-1.3	-0.5	0.9	-0.1	0.1	1.6	0.8
Taking other prescription medications	0.7	1.0	5.1	0.9	-1.1	1.2	-2.3	-0.1	0.7	0.4	-0.9	0.5	1.2	-0.3
Worrier / anxious feelings	0.7	1.3	3.5	0.4	0.5	1.4	1.8	1.6	-0.3	0.7	1.9	1.2	0.7	0.8
Number of live births	0.7	0.9	3.5	-1.1	-1.6	1.9	-0.1	-0.7	-0.5	-0.5	-1.1	-0.6	-0.6	-0.5
Medication for pain relief, constipation, heartburn	0.7	1.2	5.1	0.2	0.8	1.1	0.4	-0.2	0.7	-1.8	-0.5	-0.7	-1.4	-2.3
Migraine (self-reported)	0.7	0.8	1.9	0.6	0.7	0.1	0.2	0.8	1.3	1.1	1.1	0.9	1.4	0.9
Mean time to correctly identify matches	0.7	1.3	3.9	-1.1	-0.0	-0.2	-1.9	-2.0	-1.9	-0.6	-0.8	-1.0	-0.1	-0.7
Had major operations	0.7	0.9	4.1	-1.0	0.0	-0.2	-0.9	-0.1	-1.1	0.7	0.1	-1.2	0.3	2.0
Age at last live birth	0.7	1.1	2.9	-0.6	-1.2	1.0	-1.2	-1.5	-0.1	-1.3	-1.7	-0.2	-0.4	-0.7
Commuting to job workplace: Car/motor vehicle	0.7	0.8	2.4	-0.7	-0.6	-1.0	-1.6	-0.3	-0.5	-1.3	0.0	-0.7	-0.8	-1.1
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	0.7	0.8	4.7	0.5	0.3	-0.3	0.2	1.3	0.4	0.8	2.2	0.6	0.7	0.5
Ever had bowel cancer screening	0.7	0.8	1.8	1.2	0.2	1.4	-1.0	0.4	0.3	0.4	0.8	0.8	1.2	-0.9
Average weekly beer plus cider intake	0.7	1.0	3.8	1.0	0.1	-1.3	1.9	0.8	1.3	0.8	-0.0	0.6	1.0	0.1
Ever had prostate specific antigen (PSA) test	0.7	0.9	1.9	1.2	1.3	1.2	-0.5	1.4	0.3	0.8	-0.1	0.8	1.1	0.3
Heart attack/myocardial infarction (self-reported)	0.7	0.9	5.3	0.7	0.5	1.1	0.3	0.5	0.2	2.3	0.8	1.1	0.0	1.0
Fasting Glucose	0.6	0.7	2.8	0.7	1.7	-0.0	0.6	1.4	-0.1	1.0	0.1	0.1	0.8	0.8
Current tobacco smoking	0.6	1.0	3.1	0.7	0.7	-0.3	-0.7	-0.2	0.4	1.1	1.8	1.3	1.1	1.3
Relative age voice broke	0.6	0.8	2.3	-1.0	-0.7	0.8	-0.5	-1.1	-1.5	-1.0	-1.1	-0.9	-0.6	0.1
Bilateral oophorectomy (both ovaries removed)	0.6	0.7	4.2	0.9	0.5	-0.5	0.3	0.3	0.5	1.1	2.0	0.9	0.4	0.2
High blood pressure (mother)	0.6	0.8	1.9	-1.1	-1.1	-1.4	0.5	-0.2	-0.5	-0.2	-1.4	-0.9	-0.9	0.5
Waist circumference	0.6	2.0	4.4	-1.6	-2.0	-1.1	-1.7	-1.8	-1.0	-0.4	-2.1	-1.8	-0.5	0.0
Nervous feelings	0.6	1.2	3.2	0.6	0.9	0.3	1.7	1.2	0.9	0.8	1.8	0.8	1.2	0.9
Financial difficulties in last 2 years	0.6	0.8	3.2	-0.5	-1.0	-1.8	-0.6	-1.1	-1.2	-0.3	-1.1	0.4	-0.1	-0.1
Medication: Simvastatin	0.6	0.9	3.4	1.1	0.7	1.8	0.8	1.0	0.7	1.2	-0.9	0.5	0.4	0.2
Illnesses of siblings	0.6	0.8	2.2	0.6	1.2	-0.2	0.6	1.4	1.5	1.0	1.1	0.0	-0.4	0.1
Pulse rate	0.6	1.0	2.4	-1.0	-1.6	-0.8	0.4	-0.7	-1.5	0.2	-1.2	-0.6	-0.7	1.4
Lung cancer (father)	0.6	0.7	2.4	-0.7	0.1	0.3	-1.6	-1.2	0.3	-0.2	1.2	0.2	-0.5	0.8
Illnesses of mother	0.6	0.8	5.7	0.7	1.1	-0.1	0.1	0.1	0.1	-0.3	2.4	0.8	-0.0	-0.8
Medication: Seretide 50 evohaler	0.6	0.7	2.6	0.1	-1.5	-0.9	-1.6	-0.2	-0.4	-1.0	-0.2	-0.3	-0.3	-0.9
Commuting to job workplace: Walk	0.6	0.6	2.5	-0.8	-0.5	0.0	0.3	-1.6	-0.4	-1.4	-0.1	-0.8	-0.3	-0.8
Smoking status: Current	0.6	1.0	3.2	1.2	0.9	-0.4	-0.3	0.1	0.7	1.1	1.8	1.4	0.8	0.8
Medication: Bendroflumethiazide	0.6	0.9	2.3	-1.2	0.3	1.2	-1.1	-0.9	-0.9	0.3	-1.5	-1.2	-0.3	0.3
Medication: Omeprazole (e.g. Zanprol)	0.6	0.8	2.6	1.6	-0.9	0.3	1.1	0.8	0.6	0.0	0.6	0.4	-0.1	-1.6
Age at First Birth	0.5	0.8	2.3	-0.7	0.3	-0.7	-1.1	-0.9	-0.9	-1.1	-0.6	-0.5	-0.7	-1.5
Body Mass Index (BMI) (2010)	0.5	0.7	2.2	1.2	0.4	0.7	0.0	1.3	1.5	-0.2	-0.0	0.7	-0.2	-0.9
HDL Cholesterol	0.5	0.8	2.6	-0.4	-0.9	0.1	-1.4	-0.8	-1.3	-0.2	-1.6	-0.6	-0.1	-0.5
Schizophrenia (2014)	0.5	1.0	3.0	1.2	0.7	-0.3	0.6	1.6	1.7	0.8	1.4	0.1	-0.7	0.7
Type 2 Diabetes (T2D) (2012)	0.5	0.6	2.5	0.8	1.6	1.0	-0.3	0.5	0.7	0.6	-0.3	0.9	0.2	-0.2
Chronotype (morning person)	0.5	1.3	3.3	-0.6	-0.6	1.8	-1.4	-0.1	0.3	-1.2	-1.5	-1.2	0.2	-1.6
Ever used hormone-replacement therapy (HRT)	0.5	0.7	2.6	0.3	-1.2	0.1	0.0	-0.2	-0.5	1.6	0.4	1.1	0.8	0.8
Age when periods started (menarche)	0.5	1.3	4.6	1.3	0.9	0.3	1.4	1.6	2.1	0.3	0.6	0.7	-0.3	-1.2
Multivitamins +/- minerals	0.5	0.7	2.2	0.1	-1.3	-0.5	0.8	0.1	-1.5	-0.8	-0.8	0.4	0.3	-1.0
Stomach or abdominal pain in last month	0.5	0.6	1.7	0.6	1.2	0.7	1.2	1.3	-0.2	0.2	0.7	0.7	0.4	0.0
Body mass index (BMI)	0.5	2.0	4.9	-1.3	-2.2	-0.7	-1.2	-1.4	-1.2	-0.5	-2.2	-1.9	-0.9	-0.6
Alcohol usually taken with meals	0.5	0.7	2.3	-1.5	0.9	-0.1	-0.3	-0.5	-0.8	0.2	0.3	-0.9	-1.5	1.0
Ever unenthusiastic/disinterested for a whole week	0.5	0.6	2.2	0.7	0.5	0.0	-0.8	0.8	1.5	0.8	-0.7	-0.2	-0.2	1.0
Mouth/teeth dental problems	0.5	0.8	2.1	1.1	1.4	0.1	-0.9	-0.1	1.4	-0.6	1.1	-0.4	-0.6	-0.9
Heart attack	0.5	0.7	3.7	0.6	0.5	1.1	0.2	0.4	0.2	1.9	0.8	0.9	-0.1	0.6
Diabetes (self-reported)	0.5	0.8	2.0	0.7	-0.8	1.1	-0.8	0.5	0.5	1.4	-0.1	1.1	1.2	0.8
Time employed in main current job	0.5	0.6	2.4	0.3	0.1	-0.8	0.4	1.3	0.3	0.8	-1.5	0.0	0.3	0.8
Depression (self-reported)	0.5	0.5	2.5	-0.2	-0.3	0.9	1.6	-0.1	-0.1	0.2	1.1	0.3	1.0	0.1
Exposure to tobacco smoke at home	0.5	0.6	1.5	-0.9	-0.6	-0.7	0.1	-0.1	-0.7	-0.5	-1.2	-1.1	-1.2	0.1
Seen doctor (GP) for nerves, anxiety, tension or depression	0.5	0.8	2.5	-0.5	-0.4	1.5	-1.1	-1.6	-1.4	-0.0	0.4	-0.2	-0.8	0.3
Mouth/teeth dental problems: Bleeding gums	0.5	0.7	2.3	-0.6	-1.5	0.6	-1.5	-0.1	-0.9	0.4	-0.7	-0.1	0.4	0.6
Number of full brothers	0.5	0.6	2.0	0.6	-0.4	0.7	-1.4	0.1	-0.0	-1.1	0.4	0.6	0.5	-1.2
Health satisfaction	0.5	0.7	4.7	-0.4	-0.0	-1.1	-2.2	-0.5	-0.2	0.2	-0.1	0.5	0.1	0.8
Qualifications: NVQ or HND or HNC or equivalent	0.5	0.6	4.1	0.5	2.0	-0.4	0.8	-0.2	0.3	1.3	-0.0	0.1	0.2	0.3
Eye problems/disorders: Cataract	0.5	0.6	2.1	-1.5	-0.2	0.0	-0.3	-0.9	-1.3	-0.0	0.3	-0.9	-0.2	1.1
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.5	0.6	3.2	1.0	-0.0	0.2	0.2	0.5	0.2	0.5	0.4	1.1	1.8	0.4
Osteoporosis (self-reported)	0.5	0.7	2.3	0.0	-0.7	0.0	-0.7	-0.1	0.5	1.0	0.8	0.6	1.2	1.5
Number of self-reported non-cancer illnesses	0.5	0.9	4.8	0.6	-0.0	0.5	-2.2	0.2	-0.4	0.8	-0.5	1.4	0.8	0.4
Hearing aid user	0.5	0.5	1.9	1.4	0.2	0.2	-0.8	0.9	1.1	0.7	0.5	0.6	-0.1	0.1
Medication: Lisinopril	0.5	0.6	2.3	0.3	0.7	-0.1	-1.5	-0.4	-0.0	0.3	1.4	0.9	-0.5	0.9
Illnesses of father: High blood pressure	0.5	0.7	2.3	-0.8	-0.1	-0.4	-0.3	-0.8	-0.7	-0.7	-0.2	-1.5	-1.4	-0.6
Deep venous thrombosis (DVT) (self-reported)	0.5	0.6	1.6	0.7	0.4	-0.6	0.9	1.0	0.6	1.3	0.3	0.7	0.3	1.2
Schizophrenia vs Biploar Disorder	0.4	0.5	2.9	-0.8	0.2	-0.2	0.3	0.0	-0.1	0.1	-1.0	-0.4	-1.7	0.9
Worry (Nagel 2018)	0.4	0.9	3.1	-0.1	0.4	0.8	1.8	1.1	0.1	0.9	1.3	0.9	0.4	1.2
Alzheimer’s Disease (in father)	0.4	0.4	2.3	-0.0	0.6	-0.0	-1.0	-0.5	0.3	0.5	-1.5	-0.1	-0.3	0.6
Bipolar Disorder (2011)	0.4	0.4	2.6	0.2	-1.6	0.6	0.8	-0.1	0.0	-0.8	0.0	-0.3	-0.5	0.0
Coronary Artery Disease (CAD)	0.4	0.5	2.0	-0.5	0.6	-0.5	-0.0	0.2	-0.4	1.0	-0.5	-0.1	0.9	1.4
Triglycerides	0.4	0.7	3.6	-1.2	0.0	-1.9	0.5	-0.5	-0.6	-0.8	-1.0	0.0	-0.6	0.7
Ulcerative Colitis	0.4	0.5	1.3	-0.1	0.4	-1.1	1.1	0.7	0.0	0.4	0.1	-0.2	1.0	1.1
Blood Red Count	0.4	3.6	9.1	-3.0	-0.7	1.5	-2.3	-2.1	-2.1	-0.7	-1.1	-2.7	-2.0	0.6
Blood White Count	0.4	3.1	8.6	2.9	0.2	0.6	0.1	1.8	2.8	2.5	1.2	2.4	-0.0	1.0
Number of treatments/medications taken	0.4	0.8	2.3	0.0	-1.0	0.0	-1.5	-0.9	-0.8	1.1	-0.7	0.3	0.8	1.1
Other serious medical condition/disability diagnosed by doctor	0.4	0.5	1.9	-1.0	-0.3	-0.2	-1.1	-1.4	-0.7	0.2	-0.3	-0.5	0.0	0.7
Ever had hysterectomy (womb removed)	0.4	0.5	1.6	0.8	0.1	0.2	-0.3	0.7	0.5	0.7	1.3	1.1	0.7	0.0
Vitamin and mineral supplements	0.4	0.5	2.5	-0.6	0.3	-0.6	-1.6	-0.6	0.4	0.1	0.1	-1.1	-0.1	0.3
Maternal smoking around birth	0.4	0.6	1.5	1.0	0.0	1.2	0.8	0.4	1.1	0.2	-0.1	0.6	1.2	-0.6
Heel bone mineral density (BMD) T-score, automated (left)	0.4	0.8	2.0	-1.2	0.1	-1.1	-0.5	-0.8	-0.6	-1.4	-0.1	-1.3	-0.9	-0.9
Number of incorrect matches in round	0.4	0.7	2.9	-1.1	1.2	0.2	0.1	-0.0	-0.3	-0.2	-1.3	-1.7	-0.4	-0.1
Noisy workplace	0.4	0.5	2.1	1.2	-0.3	-0.3	1.4	0.2	0.0	-0.2	-0.9	0.4	0.1	-1.0
Loud music exposure frequency	0.4	0.4	2.1	0.7	1.4	-0.5	0.3	-0.0	0.6	-0.2	-0.1	0.3	-0.3	-1.1
Blood clot in the leg (DVT)	0.4	0.5	1.2	0.6	0.4	-0.6	0.9	0.7	0.2	1.1	0.3	0.8	-0.0	1.0
Medication: Paracetamol	0.4	0.6	4.2	-0.1	0.1	-2.1	-0.6	-0.3	-0.7	0.3	0.6	0.9	0.5	0.5
Exposure to tobacco smoke outside home	0.4	0.6	2.0	-0.3	-1.4	0.9	0.5	0.5	-0.4	0.1	0.6	-1.4	0.5	0.7
Age at first live birth	0.4	0.7	3.1	-0.9	-0.7	0.5	-1.8	-0.8	-0.4	-1.0	-0.8	-0.7	-0.7	-0.3
Eye problems/disorders: None of the above	0.4	0.4	1.7	1.0	0.2	-0.4	0.2	0.7	0.8	0.0	-0.0	0.5	-0.6	-1.3
Pulse rate, automated reading	0.4	1.4	4.0	0.5	0.9	0.5	1.5	1.1	0.0	1.8	0.9	0.9	1.2	2.0
Handedness (chirality/laterality): Left-handed	0.4	0.5	2.1	-0.6	0.3	0.2	0.8	-0.3	-0.2	-0.5	1.4	-0.8	-0.8	-0.6
Diabetes diagnosed by doctor	0.4	0.7	2.0	0.7	-1.1	1.4	-1.0	-0.1	0.4	1.2	-0.0	0.7	0.7	0.3
Medication: Blood pressure	0.4	0.7	2.5	-0.0	-0.1	0.1	-0.7	0.0	-0.3	1.5	-1.6	-1.0	0.7	1.0
High cholesterol (Self-reported)	0.4	0.8	4.6	0.9	0.2	2.2	0.2	0.4	0.6	0.8	0.7	0.9	0.6	0.0
Number of operations (self-reported)	0.4	0.7	2.1	-0.7	0.4	-0.3	-0.1	-0.4	-1.2	1.3	-0.3	-0.7	0.8	1.5
Alcohol drinker status: Previous	0.4	0.5	1.8	-0.3	-0.7	0.5	-0.7	-0.0	-0.1	0.2	-1.3	-1.0	0.9	-0.2
Intelligence (Savage-Jansen 2018)	0.3	1.0	3.8	-0.6	-1.7	-1.2	-0.8	-0.5	-0.2	-1.0	1.9	-0.2	-0.5	-0.8
Schizophrenia (2018)	0.3	0.7	2.7	0.3	0.1	-0.5	-0.9	0.6	0.6	-0.0	1.5	-0.7	-1.6	0.5
Crohns Disease (2012)	0.3	0.5	1.4	1.2	0.3	0.4	0.5	1.1	0.9	0.5	-0.2	0.9	0.8	0.5
LDL Cholesterol	0.3	0.5	1.9	-1.1	0.5	-1.4	-0.3	-0.9	-0.2	-0.4	0.6	-0.0	0.0	0.9
Blood Platelet Count	0.3	3.3	10.0	0.3	-0.1	-2.2	1.7	2.7	0.0	2.7	0.0	1.6	0.9	3.2
Heel T-Score	0.3	2.3	6.8	-0.9	0.1	0.3	-0.7	-0.8	-0.6	-2.6	-2.1	-1.5	-1.7	-2.6
Systolic Blood Pressure	0.3	1.3	4.7	0.5	-1.1	0.1	0.7	-0.1	0.5	-1.2	1.6	0.4	-1.8	-2.2
Cardiovascular Disease	0.3	1.0	3.5	-0.2	0.2	1.2	0.8	0.7	-0.8	1.6	0.7	0.7	0.2	1.9
Hand grip strength (left)	0.3	0.9	4.9	-0.4	-1.0	-2.2	0.5	0.8	-0.5	0.0	0.6	-0.7	-1.1	-0.1
Relative age of first facial hair	0.3	0.7	3.1	1.0	0.8	1.8	0.2	0.9	-0.2	-0.2	-0.5	0.8	0.6	-0.5
Systolic blood pressure, automated reading	0.3	0.7	1.6	-0.7	-0.7	-0.4	1.0	-0.5	0.2	-1.1	-0.7	-0.8	-1.2	-1.3
Hand grip strength (right)	0.3	0.7	3.9	-0.3	-1.0	-2.0	0.9	0.6	-0.4	0.7	-0.3	-0.1	-0.7	0.8
Tinnitus: Yes, but not now, but have in the past	0.3	0.4	1.6	-0.1	1.3	0.8	-0.1	0.4	0.2	0.5	-0.1	-0.7	-0.6	0.7
Supplements: Glucosamine	0.3	0.4	2.4	-0.1	-0.1	-1.6	0.8	0.2	-0.9	0.2	-0.3	-0.5	0.2	0.1
Hearing difficulty/problems with background noise	0.3	0.4	1.9	-0.1	-0.4	0.4	0.2	-0.9	-0.1	-1.0	-0.7	0.2	0.2	-1.4
Heel bone mineral density (BMD) T-score, automated (right)	0.3	0.6	1.8	-0.8	0.5	-0.4	-0.2	-0.7	-0.6	-1.4	-0.1	-0.8	-0.8	-1.2
Fluid intelligence score	0.3	0.6	2.7	-0.2	-1.5	-0.4	0.0	-0.1	-0.9	-0.1	1.6	0.5	-0.9	-0.0
Happiness	0.3	0.3	1.2	0.0	0.5	0.4	-0.6	0.5	0.1	1.0	-0.2	0.2	-0.3	1.1
Qualifications: A levels/AS levels or equivalent	0.3	0.6	1.8	-1.0	-1.2	-0.4	0.5	0.1	-0.7	-0.4	-1.0	-0.5	-1.3	-0.2
Medication: Cholesterol lowering	0.3	0.5	1.4	0.8	-0.1	1.0	-0.1	0.2	0.7	0.9	0.4	1.1	1.2	0.4
Prospective memory result	0.3	0.4	1.4	-0.2	1.2	-0.1	-1.0	-0.1	-0.3	0.3	-0.7	-0.5	0.5	0.4
Pulse wave Arterial Stiffness index	0.3	0.4	1.5	-0.1	0.8	1.2	-0.1	0.5	0.6	0.1	-0.4	-1.0	0.1	-0.1
Standing height	0.3	2.6	5.7	1.6	1.9	-1.5	2.2	1.7	1.3	0.9	1.9	2.4	0.6	1.0
Hair/balding pattern: Pattern 4	0.3	0.8	3.3	-0.5	-0.8	1.8	-1.0	-1.0	-0.7	-0.7	-0.8	0.2	-1.2	-0.1
Glaucoma (self-reported)	0.3	0.4	2.8	0.2	-0.1	1.7	0.8	0.1	0.1	0.1	-0.0	0.2	0.1	0.7
Gout (self-reported)	0.3	0.4	1.7	-0.6	0.3	-0.4	-1.3	-0.9	-0.4	-0.3	-0.4	-0.7	-0.2	-0.7
Medication: Amlodipine	0.3	0.4	1.5	-0.4	0.2	0.1	-0.2	-0.6	-1.2	0.6	-0.8	-0.2	0.9	0.6
Pulse wave peak to peak time	0.3	0.3	1.8	0.1	-0.5	-1.4	0.2	-0.4	-0.4	-0.0	0.4	1.0	-0.1	0.2
Leg fat mass (right)	0.3	1.0	2.9	-1.3	-1.4	-0.7	-0.3	-0.7	-0.9	-0.5	-1.6	-1.7	-0.3	-0.1
Overall health rating	0.3	0.6	2.4	-0.0	-0.7	-1.1	-0.4	-0.3	-0.3	-1.0	-1.6	-0.5	-0.5	-1.1
Chest pain or discomfort	0.3	0.4	2.3	-0.3	0.1	-0.6	-1.5	-0.7	-0.3	-0.4	-0.4	-0.3	-0.3	-0.6
Back pain experienced in last month	0.3	0.4	2.0	-0.4	-0.2	-0.3	0.6	-0.5	-0.9	0.0	-0.6	-1.4	0.3	0.1
Osteoarthritis (self-reported)	0.3	0.3	0.8	0.5	-0.3	-0.1	0.4	-0.1	-0.9	-0.6	-0.6	0.8	-0.8	-0.6
Medication: Gliclazide	0.3	0.3	1.0	0.4	-0.1	0.5	0.4	0.2	1.0	0.0	0.4	-0.2	-0.6	-1.0
Illnesses of father: None of the above (group 1)	0.3	0.4	1.1	-0.6	-0.3	-0.9	-0.4	-1.1	0.2	-0.3	-0.5	-0.2	-1.0	0.1
Average weekly champagne plus white wine intake	0.3	0.4	1.5	0.4	0.7	1.2	0.2	0.7	-0.1	0.4	1.1	0.6	-0.4	0.4
Eye problems/disorders: Glaucoma	0.3	0.3	2.0	0.4	-0.2	1.4	-0.1	0.0	0.4	0.1	-0.4	0.3	0.1	0.8
Arm fat-free mass (left)	0.3	1.3	2.9	-1.0	-1.7	-1.7	-0.5	-1.3	-1.1	-0.6	-1.7	-0.7	-0.7	-0.1
Age started oral contraceptive pill	0.3	0.3	1.7	-0.1	-0.1	0.3	0.1	-0.5	-1.1	0.0	-1.3	0.4	0.4	0.0
Ever depressed for a whole week	0.3	0.4	1.3	-0.2	1.1	-1.1	-1.2	-0.5	-0.1	0.1	-0.7	0.0	0.2	0.1
Leg fat mass (left)	0.3	1.1	3.1	-1.3	-1.3	-1.0	-0.3	-0.7	-0.9	-0.4	-1.8	-1.7	-0.1	-0.1
Arm predicted mass (left)	0.3	1.5	3.3	-1.2	-1.5	-1.7	-0.5	-1.5	-1.3	-0.7	-1.8	-0.9	-1.0	-0.1
Ulcerative Colitis (UC)	0.2	0.3	1.4	0.4	-0.6	0.2	1.2	0.6	0.4	0.3	0.5	0.4	0.5	0.6
Waist Hip Ratio (WHR)	0.2	1.0	2.4	-0.0	-1.6	-1.3	-1.4	-0.8	1.2	0.7	0.3	0.5	0.5	1.2
Diabetes (mother)	0.2	0.2	0.7	0.4	-0.5	0.2	0.2	-0.3	-0.2	0.9	0.4	0.6	-0.2	0.6
Leg fat-free mass (left)	0.2	1.2	3.9	-0.8	-1.5	-1.5	-1.0	-1.3	-0.7	-0.3	-2.0	-1.1	-0.5	-0.2
Serious illness, injury or assault to yourself	0.2	0.3	1.5	-0.4	-1.2	0.7	-0.4	-0.2	-0.2	-0.4	-0.4	-0.5	-0.3	-0.3
Chronic bronchitis/emphysema (father)	0.2	0.2	1.0	-0.0	-0.5	0.1	-0.2	0.3	-0.9	-0.1	-1.0	-0.3	0.6	-0.1
Leg predicted mass (left)	0.2	1.3	4.0	-0.8	-1.5	-1.5	-1.0	-1.3	-0.7	-0.3	-2.0	-1.1	-0.6	-0.2
Hair/balding pattern: Pattern 2	0.2	0.3	0.9	-0.6	-0.5	-0.9	0.1	-0.4	-0.2	-0.4	-0.7	-0.4	0.8	-0.1
Medication: Ramipril	0.2	0.3	1.3	-0.0	-1.1	0.1	-0.7	-0.6	-0.6	0.1	-0.6	0.3	0.3	-0.3
Weight	0.2	0.9	2.6	-0.8	-1.3	-1.4	-0.5	-0.9	-0.8	-0.4	-1.6	-1.0	-0.5	-0.3
Arm fat percentage (right)	0.2	0.6	2.1	-0.7	-1.5	-0.4	-0.4	-0.5	-0.5	0.3	-1.2	-1.3	-0.1	0.4
Trunk fat-free mass	0.2	1.2	2.7	-0.8	-1.4	-1.4	-0.7	-1.2	-1.1	-0.7	-1.6	-0.7	-1.1	-0.3
Frequency of tiredness / lethargy in last 2 weeks	0.2	0.3	1.5	-0.1	-0.3	-0.7	-0.4	0.0	-0.3	0.3	-0.1	-0.1	1.2	0.6
Falls in the last year	0.2	0.2	0.5	0.1	-0.0	-0.7	-0.3	-0.5	-0.7	-0.0	0.4	0.6	0.0	-0.6
Hair/balding pattern: Pattern 3	0.2	0.3	1.9	-0.4	-0.8	-0.1	-0.8	0.1	-0.1	-0.3	1.4	0.0	-0.5	0.0
Medication: Lansoprazole	0.2	0.2	1.6	0.3	-0.0	0.1	-1.3	-0.3	-0.2	-0.0	0.3	0.4	0.1	-0.1
Arm fat mass (right)	0.2	0.9	2.9	-0.9	-1.7	-1.1	-0.5	-0.7	-0.9	0.2	-1.4	-1.1	-0.2	0.4
Trunk predicted mass	0.2	1.2	2.8	-0.8	-1.4	-1.4	-0.7	-1.2	-1.1	-0.7	-1.7	-0.7	-1.1	-0.3
Length of working week for main job	0.2	0.2	1.0	0.2	0.0	-1.0	-0.1	-0.1	-0.6	-0.7	0.2	-0.6	-0.4	0.3
Qualifications: O levels/GCSEs or equivalent	0.2	0.3	1.5	-0.1	0.2	-0.6	1.2	0.0	0.6	0.2	-0.8	0.2	0.0	0.7
Leg fat percentage (right)	0.2	0.6	2.4	-1.0	-1.4	-0.2	-0.0	-0.4	-0.8	-0.5	-0.8	-1.5	-0.1	-0.1
Arm fat-free mass (right)	0.2	1.2	3.4	-0.9	-1.2	-1.8	-0.5	-1.1	-0.8	-0.5	-1.8	-0.7	-1.0	-0.1
Mouth/teeth dental problems: Loose teeth	0.2	0.2	1.5	-0.0	-0.3	-0.3	0.1	0.2	-0.5	-0.3	-0.4	1.2	0.3	0.5
Neck or shoulder pain in last month	0.2	0.2	1.0	0.3	-0.1	0.6	1.0	-0.1	-0.4	-0.3	0.4	-0.0	0.3	-0.5
Medication: Blood pressure	0.2	0.3	1.1	-0.1	0.7	1.1	0.1	-0.3	-0.6	-0.6	-0.1	1.0	0.0	-0.4
Heart disease (mother)	0.2	0.2	1.3	0.2	-0.8	0.2	0.4	0.3	0.3	0.2	-1.1	0.1	-0.1	0.0
Arm predicted mass (right)	0.2	1.0	3.2	-0.8	-1.2	-1.8	-0.4	-1.0	-0.8	-0.7	-1.6	-0.8	-0.7	-0.4
Alcohol intake frequency.	0.2	0.5	2.8	0.3	0.4	-0.5	0.8	0.2	-0.0	0.1	-1.7	-0.4	0.2	-0.9
Comparative height size at age 10	0.2	1.0	3.0	-0.4	-0.9	-1.7	-0.6	-1.4	-1.1	-1.1	-0.7	1.0	0.1	-0.6
Number of full sisters	0.2	0.3	1.1	0.1	-0.6	-0.1	0.3	-0.1	0.3	-0.7	-0.1	-0.6	-0.5	-1.0
Supplements: Vitamin C	0.2	0.3	0.8	-0.6	-0.0	-0.7	-0.1	-0.1	-0.5	0.1	0.9	0.2	-0.9	0.4
Knee pain experienced in last month	0.2	0.3	1.0	-0.4	0.3	-0.2	-0.7	-0.1	-0.3	-0.6	-0.6	-1.0	-0.1	-0.5
Hypertension (Self-reported)	0.2	0.5	2.9	-0.6	0.1	0.2	0.1	-0.8	-0.9	0.4	-1.7	-0.3	0.1	0.6
Forced expiratory volume in 1-second (FEV1), predicted	0.2	0.3	1.3	0.5	0.5	0.7	0.6	-0.0	0.7	-0.3	-0.2	1.1	-0.8	-0.2
Whole body fat-free mass	0.2	1.2	3.1	-0.8	-1.4	-1.6	-0.8	-1.3	-0.9	-0.6	-1.8	-0.8	-0.9	-0.3
Leg fat-free mass (right)	0.2	1.3	3.3	-0.9	-1.4	-1.8	-1.1	-1.2	-0.7	-0.4	-1.7	-1.2	-0.7	-0.4
Whole body water mass	0.2	1.3	3.1	-0.8	-1.5	-1.6	-0.8	-1.3	-0.8	-0.7	-1.8	-0.9	-0.9	-0.4
Leg predicted mass (right)	0.2	1.2	3.2	-0.8	-1.4	-1.8	-1.0	-1.2	-0.7	-0.3	-1.8	-1.1	-0.7	-0.4
Medication: Paracetamol	0.2	0.3	1.7	0.1	1.3	-0.7	-0.3	-0.2	-0.4	-0.0	0.6	0.9	-0.2	0.2
Basal metabolic rate	0.2	1.2	3.1	-0.9	-1.5	-1.8	-0.7	-1.2	-0.9	-0.6	-1.7	-0.9	-0.8	-0.3
Leg fat percentage (left)	0.2	0.6	2.3	-1.0	-1.2	-0.6	-0.1	-0.2	-0.6	-0.4	-0.9	-1.5	0.0	-0.2
Fractured/broken bones in last 5 years	0.2	0.2	0.7	-0.2	0.1	0.9	-0.5	0.1	0.3	0.2	0.5	0.4	0.1	0.8
Diastolic blood pressure, automated reading	0.2	0.7	4.9	0.1	0.4	-0.5	2.2	0.7	0.7	-0.6	0.1	0.1	-0.8	-0.6
Myopia	0.2	0.3	1.5	0.3	1.2	-0.1	0.5	-0.2	-0.0	0.5	-0.2	0.5	0.6	0.2
Pain experienced in last month	0.2	0.3	0.8	0.6	0.8	-0.1	-0.4	-0.1	-0.1	0.1	0.9	0.6	-0.5	-0.4
BMI	0.1	0.5	2.0	-0.1	-1.4	0.3	-0.9	0.3	-0.1	0.6	-1.4	-0.3	-0.1	0.1
Height	0.1	1.4	6.1	0.8	1.0	-0.8	0.7	0.4	1.0	1.1	2.5	1.2	-0.0	1.8
Tanning	0.1	0.9	2.6	-0.6	-0.6	1.6	-1.2	-0.5	-0.7	0.7	-1.1	-0.4	-1.3	0.4
Trunk fat percentage	0.1	0.6	1.7	0.5	-0.0	-0.4	0.9	1.0	0.7	1.3	0.2	0.1	1.0	1.0
High blood pressure	0.1	0.4	1.4	-0.5	-0.5	0.3	0.4	-0.6	-0.9	0.5	-1.2	-0.0	0.0	0.8
Trunk fat mass	0.1	0.3	0.8	-0.0	-0.4	-0.8	0.4	0.5	0.2	0.9	-0.5	-0.3	0.6	0.8
Forced vital capacity (FVC)	0.1	0.5	1.9	-0.4	-0.5	-1.0	-0.6	-0.5	-0.6	-0.7	0.6	-0.4	-1.4	-0.6
Qualifications: None of the above	0.1	0.3	0.7	-0.2	0.2	0.8	-0.0	0.2	-0.1	-0.6	-0.6	-0.8	0.4	-0.7
Hip circumference	0.1	0.6	2.2	-1.0	-0.7	-0.7	0.2	-0.5	-1.0	-0.3	-1.5	-1.2	-0.3	-0.2
Forced expiratory volume in 1-second (FEV1)	0.1	0.3	1.1	-0.4	-0.3	-0.6	-0.0	-0.5	-0.8	-0.2	1.0	-0.1	-0.9	-0.1
Forced expiratory volume in 1-second (FEV1), Best measure	0.1	0.4	0.9	-0.6	-0.0	-0.9	0.8	-0.7	-0.6	-0.0	0.6	-0.5	-1.0	-0.1
Peak expiratory flow (PEF)	0.1	0.3	1.4	0.3	-0.3	0.3	0.3	-0.2	0.0	0.4	0.7	-0.0	1.2	0.7
Birth weight	0.1	0.2	0.8	0.0	0.1	0.1	0.3	-0.1	-0.4	-0.0	-0.2	-0.5	0.7	-0.9
Forced vital capacity (FVC), Best measure	0.1	0.5	2.0	-0.4	-0.2	-1.1	-0.0	-0.8	-0.5	-0.6	0.6	-0.5	-1.4	-0.8
Body fat percentage	0.1	0.2	0.5	-0.1	-0.6	-0.4	0.4	0.4	0.2	0.5	-0.4	-0.7	0.6	0.4
Whole body fat mass	0.1	0.3	0.8	-0.4	-0.9	-0.8	0.1	0.0	-0.0	0.5	-0.8	-0.7	0.4	0.5
Suffer from ‘nerves’	0.1	0.2	1.5	0.1	0.3	-1.2	0.2	0.2	-0.1	-0.2	0.1	0.2	0.1	0.2
Arm fat percentage (left)	0.1	0.4	1.5	-0.4	-1.2	-0.2	-0.4	-0.1	-0.1	0.6	-0.9	-1.1	0.2	0.5
Arm fat mass (left)	0.1	0.5	1.9	-0.5	-1.4	-0.9	-0.4	-0.4	-0.4	0.4	-1.1	-0.8	-0.1	0.5
Vascular/heart problems diagnosed by doctor	0.1	0.3	0.8	0.2	0.4	-0.9	-0.4	0.3	0.3	-0.8	0.8	-0.3	-0.2	-0.5
Hair Pigment	0.0	0.7	2.5	-0.8	-1.0	-1.0	0.3	0.2	-0.9	0.6	-0.3	-0.8	0.9	1.6
Sitting height	0.0	0.3	2.0	-0.3	-0.1	-1.4	-0.2	-0.1	-0.1	-0.4	0.5	0.7	-0.8	-0.0

Hub : Genes

FBXO18

Models

Trait associations