TWAS hub - FAM208B

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Heart Atrial Appendage	0.230	0.080	0.0065	0.023	NA	-0.005	NA	0.06	0.0310	NA	0.6800	NA	0.0012
2	GTEx	Skin Sun Exposed Lower leg	0.101	0.038	0.0062	0.031	NA	0.020	NA	0.03	0.0012	NA	0.0081	NA	0.0014

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2
Hypothyroidism (self reported)	17.4	40.1	78.5	1.3	-8.9
Hypothyroidism/myxoedema (self-reported)	16.6	32.3	63.2	1.2	-8.0
Medication: Levothyroxine sodium	15.6	26.5	52.0	1.0	-7.2
Taking other prescription medications	11.5	17.7	35.4	0.3	-6.0
Rheumatoid Arthritis	10.0	13.8	25.5	1.4	-5.0
Number of self-reported non-cancer illnesses	6.7	11.6	18.6	2.1	-4.3
Long-standing illness, disability or infirmity	6.6	10.1	20.1	-0.3	-4.5
Asthma (self-reported)	5.9	11.7	12.2	-3.3	-3.5
Respiratory disease	5.8	12.8	19.2	-2.5	-4.4
Allergy	5.6	12.9	17.2	4.1	2.9
Number of treatments/medications taken	5.4	9.7	18.8	0.7	-4.3
Asthma	5.4	10.6	11.2	-3.3	-3.2
Blood Eosinophil Count	4.8	37.1	43.6	-5.5	-6.6
Average weekly red wine intake	4.3	6.3	7.1	2.4	2.7
Diabetes diagnosed by doctor	4.3	7.1	11.0	1.8	-3.3
Alcohol drinker status: Previous	4.2	4.7	7.4	1.4	-2.7
Hayfever, allergic rhinitis or eczema	4.0	8.7	15.9	-4.0	-1.2
Wheeze or whistling in the chest in last year	3.8	6.8	11.9	-1.3	-3.4
Prostate Cancer	3.7	5.2	10.1	-3.2	-0.5
Diabetes (self-reported)	3.7	5.7	7.8	1.9	-2.8
Medication: Omeprazole	3.3	3.9	5.0	2.2	-1.7
Other serious medical condition/disability diagnosed by doctor	3.2	4.1	8.2	0.2	-2.9
Medication: Allopurinol	3.2	4.3	8.1	-0.6	-2.9
Number of full sisters	3.2	3.9	4.8	-1.7	2.2
Eye problems/disorders: Diabetes related eye disease	3.0	3.3	4.4	2.1	-1.5
Allergy or Eczema	2.9	7.6	13.8	-3.7	-1.2
Medication: Metformin	2.9	4.1	5.5	1.6	-2.4
Supplements: Fish oil (including cod liver oil)	2.8	3.7	4.3	1.7	2.1
Medication: Omeprazole (e.g. Zanprol)	2.8	3.4	3.8	1.9	-1.8
Emphysema/chronic bronchitis	2.7	3.0	5.9	0.4	-2.4
Bipolar Disorder (2011)	2.6	2.5	4.8	-2.2	-0.5
Father’s age at death	2.6	3.5	7.1	2.7	0.2
Medication: Lansoprazole	2.6	3.0	5.9	-0.3	-2.4
Mean Putamen Volume	2.4	2.8	3.6	1.4	1.9
Health satisfaction	2.3	3.0	5.2	2.3	-0.9
Medication for pain relief, constipation, heartburn	2.3	4.0	7.7	0.6	2.8
Illnesses of father: Heart disease	2.3	3.2	6.2	0.3	2.5
Alzheimer’s Disease (in mother)	2.2	2.6	4.3	1.0	-2.1
Medication: Atenolol	2.2	2.7	3.7	1.3	-1.9
Leg pain on walking	2.2	2.8	5.6	2.4	0.0
Medication: Aspirin	2.2	2.9	4.9	0.9	-2.2
Medication: Aspirin	2.2	2.9	5.2	0.8	-2.3
Ever had bowel cancer screening	2.1	2.5	3.0	1.7	-1.4
Mouth/teeth dental problems: Mouth ulcers	2.0	3.2	5.8	0.7	2.4
Ulcerative Colitis (UC)	1.9	3.6	4.8	1.6	-2.2
Medication: Ventolin 100micrograms inhaler	1.9	2.5	2.7	-1.6	-1.5
Financial situation satisfaction	1.9	2.3	4.6	0.1	2.1
Commuting to job workplace: Cycle	1.9	2.2	4.4	-0.3	2.1
Deep venous thrombosis (DVT) (self-reported)	1.9	2.4	4.4	0.7	-2.1
Type 2 Diabetes (T2D) (2018)	1.8	3.4	5.9	1.0	-2.4
Ever had hysterectomy (womb removed)	1.8	2.0	2.5	1.3	-1.6
Number of live births	1.8	2.5	3.1	1.4	-1.8
Happiness	1.8	2.1	2.5	1.3	1.6
Ever highly irritable/argumentative for 2 days	1.8	2.1	4.2	-2.1	0.2
Ulcerative Colitis	1.7	2.4	2.6	1.5	-1.6
Had menopause	1.7	2.1	4.0	-0.4	-2.0
Time employed in main current job	1.7	2.0	2.3	-1.3	-1.5
Commuting to job workplace: Walk	1.7	1.8	2.5	1.1	1.6
Blood clot in the leg (DVT)	1.6	2.1	3.8	0.6	-2.0
Migraine (self-reported)	1.6	2.0	4.0	-0.2	-2.0
Reproduciblity of spirometry measurement using ERS/ATS criteria	1.6	1.9	2.2	1.5	1.3
Osteoporosis (self-reported)	1.6	2.0	4.0	0.2	-2.0
Hearing aid user	1.6	1.8	2.6	1.0	-1.6
Neck or shoulder pain in last month	1.5	2.1	2.3	1.4	1.5
Illnesses of siblings: Diabetes	1.5	1.9	2.7	-1.6	-1.1
Mineral and other dietary supplements	1.5	2.1	2.7	-1.6	-1.2
Bilateral oophorectomy (both ovaries removed)	1.4	1.7	3.3	0.2	-1.8
Heart attack	1.4	1.8	2.3	1.1	-1.5
Illnesses of mother	1.4	1.7	3.1	-0.6	1.8
Suffer from ‘nerves’	1.4	2.3	3.1	-1.2	-1.8
Loneliness, isolation	1.4	2.0	2.5	-1.6	1.2
Wears glasses or contact lenses	1.4	1.6	2.6	-1.6	-0.8
Breast Cancer	1.3	3.1	3.2	1.8	-1.8
Supplements: Glucosamine	1.3	1.8	2.6	1.0	1.6
High blood pressure (mother)	1.3	1.8	3.3	0.5	1.8
Medication: Simvastatin	1.3	1.9	3.8	0.1	-1.9
Mouth/teeth dental problems: Loose teeth	1.3	1.5	2.6	-1.6	0.7
Breast cancer (self-reported)	1.3	1.5	3.0	-0.2	-1.7
Medication: Blood pressure	1.3	2.4	3.5	-1.2	-1.9
Basal cell carcinoma (self-reported)	1.3	1.5	3.0	0.2	1.7
Schizophrenia vs Biploar Disorder	1.2	1.6	3.2	1.8	0.3
Seen doctor (GP) for nerves, anxiety, tension or depression	1.2	1.9	3.1	1.8	-0.8
Had major operations	1.2	1.4	1.7	-1.3	-1.1
Alzheimer’s Disease (including proxy)	1.1	1.5	2.9	0.4	-1.7
Hand grip strength (left)	1.1	3.0	6.0	2.4	-0.2
Tinnitus: Yes, but not now, but have in the past	1.1	1.1	1.8	0.7	1.4
Medication: Ramipril	1.1	1.4	2.6	0.5	-1.6
Falls in the last year	1.1	1.5	2.8	0.4	-1.7
Qualifications: O levels/GCSEs or equivalent	1.1	1.8	3.1	-0.6	1.8
Gout (self-reported)	1.1	1.5	2.5	-0.7	-1.6
Medication: Ibuprofen	1.1	1.3	2.2	-1.5	0.7
Heart attack/myocardial infarction (self-reported)	1.1	1.4	1.5	1.1	-1.2
Fasting Glucose	1.0	1.2	1.4	-1.2	-1.0
Townsend deprivation index at recruitment	1.0	1.4	2.4	1.5	0.7
Stomach or abdominal pain in last month	1.0	1.3	2.4	1.6	-0.3
Pain all over the body in last month	1.0	1.1	1.7	-0.7	-1.3
Medication: Ibuprofen (e.g. Nurofen)	1.0	1.3	1.9	-1.4	0.8
Lung cancer (father)	1.0	1.1	2.3	-0.0	-1.5
Loud music exposure frequency	1.0	1.1	1.5	-0.8	1.2
Number of children fathered	1.0	1.1	2.1	-1.4	0.4
Alcohol intake frequency.	1.0	2.4	4.3	0.7	-2.1
Commuting to job workplace: Car/motor vehicle	1.0	1.1	1.6	-0.8	-1.3
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.0	1.1	2.1	0.4	-1.4
Medication for cholesterol	1.0	1.5	2.9	0.3	1.7
Diverticular disease/diverticulitis (self-reported)	0.9	1.1	2.1	0.0	-1.5
Waist circumference	0.9	3.3	6.7	-0.1	-2.6
Forced expiratory volume in 1-second (FEV1)	0.9	3.2	4.3	1.4	2.1
Medication: Cholesterol lowering	0.9	1.3	2.4	-0.5	-1.6
Qualifications: College or University degree	0.9	3.0	5.4	0.8	2.3
Heart disease (mother)	0.9	1.1	2.2	-0.1	-1.5
Overall health rating	0.9	1.9	3.6	-0.5	-1.9
Friendships satisfaction	0.9	1.1	2.0	-0.5	1.4
Bipolar Disorder (2018)	0.8	1.2	2.4	-1.6	0.1
Major Depression (MDD)	0.8	1.0	1.5	1.2	-0.7
Body Mass Index (BMI) (2010)	0.8	1.1	1.3	-1.1	0.9
Lupus	0.8	1.2	2.2	0.5	-1.5
Diabetes (mother)	0.8	1.1	2.1	-1.4	-0.2
Pack years adult smoking proportion	0.8	1.2	2.3	1.5	0.3
Hand grip strength (right)	0.8	2.2	3.5	1.9	1.0
Forced expiratory volume in 1-second (FEV1), Best measure	0.8	2.4	2.5	1.5	1.6
Exposure to tobacco smoke at home	0.8	0.9	1.7	-1.3	-0.0
Medication for cholesterol, blood pressure or diabetes	0.8	1.4	2.0	-1.4	0.9
Pulse wave peak to peak time	0.8	0.9	1.1	-0.9	1.1
Shortness of breath walking on level ground	0.8	1.0	1.3	0.8	1.1
Smoking status: Current	0.8	1.3	1.8	0.8	-1.4
Risk taking	0.8	1.2	2.4	-1.5	-0.3
Primary Biliary Cirrhosis	0.7	1.0	2.1	-1.4	0.1
BMI	0.7	3.9	7.5	0.6	-2.7
Chronotype (morning person)	0.7	1.6	2.8	-0.6	-1.7
Vitamin and mineral supplements	0.7	1.0	1.7	-1.3	-0.5
Diabetes (father)	0.7	0.9	1.2	1.1	-0.8
Current tobacco smoking	0.7	1.2	1.9	0.7	-1.4
Multivitamins +/- minerals	0.7	0.9	1.6	0.4	1.3
Frequency of tiredness / lethargy in last 2 weeks	0.7	1.1	2.2	1.5	0.3
Depression (self-reported)	0.7	0.8	1.5	1.2	0.2
Forced vital capacity (FVC), Best measure	0.7	2.5	3.4	1.9	1.2
Supplements: Vitamin C	0.7	0.8	1.5	1.2	0.3
Average weekly champagne plus white wine intake	0.7	0.9	1.7	0.3	1.3
Tinnitus: Yes, now most or all of the time	0.7	0.8	1.4	1.2	0.5
Illnesses of father: High blood pressure	0.7	0.9	1.4	-1.2	-0.7
Bipolar Disorder or Schizophrenia	0.6	1.4	1.9	-1.4	-0.9
Age at First Birth	0.6	0.9	1.4	1.2	0.6
HbA1C	0.6	0.7	1.3	-0.2	1.1
Waist Hip Ratio (WHR)	0.6	2.5	4.6	0.6	-2.1
Hearing difficulty/problems: Yes	0.6	0.9	1.8	0.0	1.4
Relative age of first facial hair	0.6	1.2	2.5	-0.1	1.6
Average weekly fortified wine intake	0.6	0.7	1.4	-1.2	0.1
Maternal smoking around birth	0.6	0.9	1.5	-1.2	-0.6
Age when periods started (menarche)	0.6	1.3	1.5	1.2	1.1
Serious illness, injury or assault to yourself	0.6	0.8	0.9	-0.8	-1.0
Frequency of tenseness / restlessness in last 2 weeks	0.6	0.9	1.7	0.2	1.3
Forced vital capacity (FVC)	0.6	2.2	2.8	1.7	1.2
Mouth/teeth dental problems	0.6	0.9	1.6	-0.4	-1.3
Chronic bronchitis/emphysema (mother)	0.6	0.7	1.1	-1.1	-0.5
Worry too long after embarrassment	0.6	0.9	1.6	-1.3	0.5
High cholesterol (Self-reported)	0.6	1.0	1.3	0.8	-1.2
Medication: Atorvastatin	0.6	0.8	1.5	-1.2	0.1
Ever had prostate specific antigen (PSA) test	0.6	0.7	1.0	-0.6	1.0
Age started oral contraceptive pill	0.6	0.8	1.3	0.5	-1.2
Diastolic blood pressure, automated reading	0.6	1.9	2.7	1.0	1.6
Ever depressed for a whole week	0.6	0.8	1.5	0.3	-1.2
Supplements: Calcium	0.6	0.6	1.2	1.1	-0.3
Pack years of smoking	0.6	0.9	1.8	1.3	0.0
Depressed Affect (Nagel 2018)	0.5	1.0	1.9	-0.1	1.4
Alzheimer’s Disease (in father)	0.5	0.6	1.1	-0.3	-1.0
Ovarian Cancer	0.5	0.7	1.3	-1.2	-0.1
HDL Cholesterol	0.5	0.8	1.5	-0.1	-1.2
Lung FVC	0.5	2.3	3.7	1.9	1.0
Neuroticism	0.5	1.3	2.4	-0.3	1.6
Angina	0.5	0.6	0.8	0.9	0.6
Severe depression (siblings)	0.5	0.5	0.9	-1.0	-0.4
Frequency of unenthusiasm / disinterest in last 2 weeks	0.5	0.7	1.4	1.2	0.2
Ever unenthusiastic/disinterested for a whole week	0.5	0.6	0.6	-0.8	-0.8
Pulse rate	0.5	0.8	1.6	1.3	0.0
Mouth/teeth dental problems: Dentures	0.5	0.8	1.7	-0.0	-1.3
Pulse wave Arterial Stiffness index	0.5	0.6	0.6	0.8	-0.7
Glaucoma (self-reported)	0.5	0.6	1.0	0.4	-1.0
Birth weight	0.5	1.1	1.3	-0.9	1.1
Medication: Seretide 50 evohaler	0.5	0.6	0.9	-0.9	-0.5
Mean time to correctly identify matches	0.5	1.0	1.7	-0.5	-1.3
Mood swings	0.5	0.9	1.1	-1.1	0.8
Irritability	0.5	0.8	0.9	-0.8	-0.9
Schizophrenia (2018)	0.4	0.9	1.4	-0.6	-1.2
Triglycerides	0.4	0.6	0.8	-0.6	0.9
Lung FEV1/FVC ratio	0.4	2.1	2.7	1.2	1.6
Trunk fat percentage	0.4	1.4	2.8	-0.1	-1.7
Sitting height	0.4	2.6	5.1	-0.3	2.3
Body mass index (BMI)	0.4	1.8	3.5	-0.4	-1.9
Fluid intelligence score	0.4	0.9	1.8	0.1	1.3
Qualifications: A levels/AS levels or equivalent	0.4	1.0	1.8	1.3	0.4
Tense / ‘highly strung’	0.4	0.7	1.4	-1.2	0.2
Birth weight of first child	0.4	0.8	1.3	0.5	1.2
Angina (self-reported)	0.4	0.5	0.6	0.8	0.6
Chest pain or discomfort	0.4	0.6	1.2	-1.1	-0.1
Arm fat percentage (left)	0.4	1.4	2.5	-0.6	-1.6
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.4	0.5	0.6	-0.6	-0.8
Mother’s age at death	0.4	0.5	0.9	1.0	0.1
Cholesterol lowering medication	0.4	0.6	0.9	-0.6	-0.9
Irritable Bowel Disease (IBD)	0.3	0.8	0.9	0.8	-1.0
Reaction Time	0.3	0.6	0.7	-0.7	-0.8
Coronary Artery Disease (CAD)	0.3	0.3	0.7	-0.1	-0.8
LDL Cholesterol	0.3	0.5	1.1	-1.0	-0.0
Systolic Blood Pressure	0.3	1.4	2.3	1.5	0.6
Cardiovascular Disease	0.3	0.9	1.7	1.3	0.2
Ever used hormone-replacement therapy (HRT)	0.3	0.4	0.6	0.8	-0.4
Medication for hormone replacement therapy	0.3	0.3	0.4	0.6	-0.6
Impedance of leg (right)	0.3	1.3	2.4	-0.4	1.5
Impedance of leg (left)	0.3	1.3	2.4	0.4	1.6
Trunk fat mass	0.3	1.3	2.7	-0.1	-1.6
Alcohol usually taken with meals	0.3	0.6	1.1	1.1	0.0
Had other major operations	0.3	0.4	0.8	-0.1	-0.9
Illnesses of siblings	0.3	0.5	0.9	1.0	-0.2
Arm fat percentage (right)	0.3	1.0	1.6	-0.6	-1.3
Arm fat mass (right)	0.3	1.2	2.3	-0.4	-1.5
Length of working week for main job	0.3	0.4	0.4	-0.6	0.6
Headache pain in last month	0.3	0.6	0.8	-0.9	-0.6
High blood pressure (siblings)	0.3	0.4	0.7	-0.8	0.3
Body fat percentage	0.3	1.3	2.5	-0.3	-1.6
Medication: Blood pressure	0.3	0.5	0.8	0.9	0.3
Whole body fat mass	0.3	1.1	2.2	-0.2	-1.5
Leg fat mass (right)	0.3	1.0	1.8	-0.4	-1.4
Qualifications: NVQ or HND or HNC or equivalent	0.3	0.4	0.6	0.8	-0.5
Illness, injury, bereavement, stress in last 2 years	0.3	0.4	0.6	0.8	0.4
Handedness (chirality/laterality): Left-handed	0.3	0.4	0.4	0.6	0.6
Ever had stillbirth, spontaneous miscarriage or termination	0.3	0.3	0.5	-0.7	-0.0
Back pain experienced in last month	0.3	0.5	0.6	0.7	0.6
Medication: Gliclazide	0.3	0.3	0.5	0.3	-0.7
Forced expiratory volume in 1-second (FEV1), predicted percentage	0.3	0.6	1.1	1.0	0.3
Arm fat mass (left)	0.3	1.1	2.0	-0.4	-1.4
Miserableness	0.3	0.5	0.5	0.7	-0.7
Ever taken oral contraceptive pill	0.3	0.3	0.4	-0.6	0.5
Pain type(s) experienced in last month: Hip pain	0.3	0.4	0.5	0.6	-0.7
Medication: Bendroflumethiazide	0.3	0.4	0.6	0.8	0.5
Average weekly beer plus cider intake	0.3	0.4	0.6	-0.5	0.7
Leg fat mass (left)	0.3	1.0	2.0	-0.3	-1.4
Depression (Nagel 2018)	0.2	0.4	0.7	0.9	-0.1
Intelligence (Savage-Jansen 2018)	0.2	0.7	1.4	0.3	1.2
Verbal and Numeric Reasoning (VNR)	0.2	0.5	0.9	-0.4	0.9
Neuroticism (2016)	0.2	0.3	0.4	-0.3	0.6
Blood White Count	0.2	1.2	2.4	-0.1	-1.5
Medication: Co-codamol	0.2	0.3	0.4	-0.6	-0.3
Past tobacco smoking	0.2	0.4	0.5	-0.7	0.6
Heel bone mineral density (BMD) T-score, automated (right)	0.2	0.4	0.6	-0.8	0.4
Qualifications: None of the above	0.2	0.5	1.0	-0.0	-1.0
Hayfever/allergic rhinitis (self-reported)	0.2	0.3	0.5	-0.0	0.7
Neuroticism score	0.2	0.5	0.5	-0.7	0.6
Serious illness, injury or assault of a close relative in last 2 years	0.2	0.2	0.4	-0.6	0.0
Prospective memory result	0.2	0.2	0.4	-0.6	-0.3
Standing height	0.2	2.4	3.8	1.0	2.0
Hair/balding pattern: Pattern 4	0.2	0.5	1.0	-1.0	-0.1
Peak expiratory flow (PEF)	0.2	0.5	0.8	0.5	0.9
Pulse wave reflection index	0.2	0.2	0.4	-0.4	-0.6
Medication: Paracetamol	0.2	0.4	0.6	0.5	-0.7
Medication: Amlodipine	0.2	0.3	0.3	-0.6	-0.6
Leg fat percentage (right)	0.2	0.9	1.2	-0.7	-1.1
Eye problems/disorders: None of the above	0.2	0.2	0.3	-0.6	0.3
Knee pain experienced in last month	0.2	0.4	0.7	0.9	-0.0
Illnesses of father: None of the above (group 1)	0.2	0.3	0.3	-0.5	0.5
Eye problems/disorders: Glaucoma	0.2	0.2	0.3	-0.5	-0.5
Medication: Lisinopril	0.2	0.3	0.4	0.3	0.6
Leg fat percentage (left)	0.2	0.7	1.3	-0.3	-1.1
Vascular/heart problems diagnosed by doctor	0.2	0.6	0.7	-0.8	0.8
Impedance of whole body	0.2	1.0	1.1	0.9	1.1
Neuroticism (Nagel 2018)	0.1	0.2	0.5	-0.1	0.7
Crohns Disease (2017)	0.1	0.3	0.3	-0.5	0.5
Crohns Disease (2012)	0.1	0.2	0.2	-0.4	-0.4
Schizophrenia (2014)	0.1	0.3	0.5	0.1	-0.7
Type 2 Diabetes (T2D) (2012)	0.1	0.1	0.2	-0.3	-0.4
Smoking Status	0.1	0.1	0.2	0.1	-0.5
Average weekly spirits intake	0.1	0.1	0.2	0.4	0.3
Sensitivity / hurt feelings	0.1	0.1	0.1	0.3	0.4
Systolic blood pressure, automated reading	0.1	0.2	0.3	0.5	0.4
Leg fat-free mass (left)	0.1	0.3	0.6	0.1	-0.8
Fed-up feelings	0.1	0.2	0.3	0.1	0.6
Heel bone mineral density (BMD) T-score, automated (left)	0.1	0.3	0.4	-0.6	0.5
Qualifications: CSEs or equivalent	0.1	0.1	0.2	-0.4	0.1
High blood pressure	0.1	0.3	0.4	0.6	-0.5
Chronic bronchitis/emphysema (father)	0.1	0.1	0.3	0.5	-0.2
Leg predicted mass (left)	0.1	0.4	0.8	-0.0	-0.9
Number of incorrect matches in round	0.1	0.1	0.2	0.1	0.4
Nervous feelings	0.1	0.1	0.2	-0.5	-0.1
Hair/balding pattern: Pattern 2	0.1	0.1	0.1	-0.3	0.3
Financial difficulties in last 2 years	0.1	0.1	0.3	0.5	-0.0
Weight	0.1	0.4	0.9	0.0	-0.9
Impedance of arm (right)	0.1	0.5	0.6	0.6	0.8
Worrier / anxious feelings	0.1	0.2	0.3	0.1	0.6
Hair/balding pattern: Pattern 3	0.1	0.2	0.2	0.3	-0.5
Impedance of arm (left)	0.1	0.3	0.4	0.6	0.5
Exposure to tobacco smoke outside home	0.1	0.2	0.3	-0.5	0.3
Age at first live birth	0.1	0.2	0.3	-0.5	0.3
Pulse rate, automated reading	0.1	0.4	0.6	0.8	0.5
Hypertension (Self-reported)	0.1	0.3	0.4	0.4	-0.6
Smoking status: Previous	0.1	0.1	0.2	-0.0	-0.5
Leg fat-free mass (right)	0.1	0.3	0.4	0.4	-0.7
Qualifications: nursing, teaching	0.1	0.1	0.1	0.4	0.1
Leg predicted mass (right)	0.1	0.3	0.5	0.4	-0.7
Guilty feelings	0.1	0.1	0.2	-0.0	0.5
Commuting to job workplace: Public transport	0.1	0.1	0.1	0.2	0.4
Medication: Paracetamol	0.1	0.2	0.2	0.4	-0.5
Alcohol drinker status: Never	0.1	0.1	0.1	0.4	0.2
Ever smoked	0.1	0.1	0.3	0.1	-0.5
Fractured/broken bones in last 5 years	0.1	0.1	0.2	-0.0	-0.4
Unable to work because of sickness or disability	0.1	0.1	0.2	-0.2	0.4
Pain experienced in last month	0.1	0.1	0.1	-0.3	-0.3
Heart disease (siblings)	0.1	0.1	0.2	0.4	-0.2
Worry (Nagel 2018)	0.0	0.1	0.1	-0.4	0.1
Blood Platelet Count	0.0	0.2	0.4	0.2	-0.6
Blood Red Count	0.0	0.1	0.2	-0.2	0.4
Heel T-Score	0.0	0.1	0.1	0.1	-0.4
Height	0.0	0.7	1.4	0.2	1.2
Hair Pigment	0.0	1.3	2.7	0.0	-1.6
Tanning	0.0	0.2	0.3	0.5	-0.4
Frequency of depressed mood in last 2 weeks	0.0	0.1	0.1	-0.3	0.2
Supplements: Zinc	0.0	0.0	0.0	0.2	-0.1
Relative age voice broke	0.0	0.1	0.1	0.1	0.4
Hearing difficulty/problems with background noise	0.0	0.0	0.1	0.2	0.1
Trunk fat-free mass	0.0	0.1	0.1	0.3	-0.1
Hip circumference	0.0	0.2	0.3	-0.3	-0.6
Alcohol intake versus 10 years previously	0.0	0.1	0.1	0.1	-0.3
Noisy workplace	0.0	0.0	0.0	-0.1	0.1
Trunk predicted mass	0.0	0.1	0.1	0.4	-0.1
Breastfed as a baby	0.0	0.0	0.0	0.0	0.0
Mouth/teeth dental problems: Bleeding gums	0.0	0.0	0.0	0.2	0.1
Arm fat-free mass (right)	0.0	0.0	0.1	0.1	-0.2
Comparative body size at age 10	0.0	0.1	0.2	0.5	0.0
Number of full brothers	0.0	0.1	0.1	0.3	-0.2
Seen a psychiatrist for nerves, anxiety, tension or depression	0.0	0.0	0.0	-0.1	-0.0
Reason for reducing amount of alcohol drunk: Health precaution	0.0	0.0	0.0	0.0	0.0
Arm predicted mass (right)	0.0	0.1	0.1	0.3	-0.3
Comparative height size at age 10	0.0	0.2	0.3	0.5	0.4
Age at last live birth	0.0	0.0	0.1	-0.3	0.1
Family relationship satisfaction	0.0	0.0	0.0	-0.0	-0.1
Forced expiratory volume in 1-second (FEV1), predicted	0.0	0.1	0.1	-0.0	0.4
Whole body fat-free mass	0.0	0.1	0.1	0.4	-0.3
Eye problems/disorders: Cataract	0.0	0.1	0.1	-0.0	-0.3
Osteoarthritis (self-reported)	0.0	0.0	0.1	-0.2	-0.1
Whole body water mass	0.0	0.1	0.1	0.3	-0.3
Basal metabolic rate	0.0	0.1	0.2	0.3	-0.4
Arm fat-free mass (left)	0.0	0.1	0.2	0.1	-0.5
Number of operations (self-reported)	0.0	0.0	0.1	0.1	0.3
Myopia	0.0	0.0	0.1	-0.1	0.3
Arm predicted mass (left)	0.0	0.2	0.3	0.5	-0.2

Hub : Genes

FAM208B

Models

Trait associations