[Hub]/) : Traits : Hypothyroidism/myxoedema (self-reported) :

chr19:17,672,385-19,190,906

Best TWAS P=2.75e-08 · Best GWAS P=7.56e-10 conditioned to 2.83e-05

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Pituitary KIAA1683 0.43 0.25 lasso 3 0.17 3.9e-05 -5.4 -5.5 3.8e-08 -0.51 0.06 0.67 FALSE
2 GTEx Vagina LRRC25 0.63 0.02 enet 2 0.04 5.3e-02 -5.5 5.5 4.7e-08 0.41 0.04 0.13 FALSE
3 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma JUND 0.05 0.04 lasso 1 0.04 4.3e-05 -5.5 -5.5 4.2e-08 -0.41 0.04 0.74 FALSE
4 The Cancer Genome Atlas Brain Lower Grade Glioma JUND 0.04 0.03 lasso 2 0.02 7.9e-04 -5.5 -5.6 2.8e-08 -0.43 0.04 0.77 TRUE