Best TWAS P=2.75e-08 · Best GWAS P=7.56e-10 conditioned to 2.83e-05
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Pituitary | KIAA1683 | 0.43 | 0.25 | lasso | 3 | 0.17 | 3.9e-05 | -5.4 | -5.5 | 3.8e-08 | -0.51 | 0.06 | 0.67 | FALSE |
2 | GTEx | Vagina | LRRC25 | 0.63 | 0.02 | enet | 2 | 0.04 | 5.3e-02 | -5.5 | 5.5 | 4.7e-08 | 0.41 | 0.04 | 0.13 | FALSE |
3 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | JUND | 0.05 | 0.04 | lasso | 1 | 0.04 | 4.3e-05 | -5.5 | -5.5 | 4.2e-08 | -0.41 | 0.04 | 0.74 | FALSE |
4 | The Cancer Genome Atlas | Brain Lower Grade Glioma | JUND | 0.04 | 0.03 | lasso | 2 | 0.02 | 7.9e-04 | -5.5 | -5.6 | 2.8e-08 | -0.43 | 0.04 | 0.77 | TRUE |