Best TWAS P=2.46e-09 · Best GWAS P=7.2e-15 conditioned to 3.3e-05
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | ROSMAP | Brain Pre-frontal Cortex | TICAM1 | 0.07 | 0.02 | lasso | 5 | 0.04 | 1.2e-05 | 7.1 | 6.0 | 2.5e-09 | 0.81 | 0.01 | 0.99 | TRUE |
| 2 | The Cancer Genome Atlas | Pancreatic Adenocarcinoma | FEM1A | 0.10 | 0.10 | lasso | 3 | 0.08 | 4.6e-04 | -5.8 | -5.6 | 2.0e-08 | -0.66 | 0.03 | 0.46 | TRUE |
| 3 | The Cancer Genome Atlas | Thyroid Carcinoma | TICAM1 | 0.07 | 0.04 | blup | 54 | 0.06 | 1.6e-06 | 6.7 | 5.5 | 4.3e-08 | 0.78 | 0.01 | 0.99 | FALSE |