Best TWAS P=2.65e-36 · Best GWAS P=1.62e-36 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Lung | VAV3 | 0.25 | 0.23 | lasso | 2 | 0.23 | 2.4e-17 | 11.4 | 11.3 | 1.4e-29 | 0.90 | 0.98 | 0.02 | FALSE |
| 2 | GTEx | Nerve Tibial | VAV3 | 0.20 | 0.07 | lasso | 5 | 0.09 | 8.8e-07 | 8.1 | 7.7 | 1.3e-14 | 0.77 | 0.13 | 0.86 | FALSE |
| 3 | GTEx | Thyroid | VAV3 | 0.36 | 0.27 | lasso | 5 | 0.29 | 2.7e-22 | 12.6 | 12.6 | 2.6e-36 | 1.00 | 0.00 | 1.00 | TRUE |
| 4 | NTR | Blood | VAV3 | 0.03 | 0.01 | lasso | 4 | 0.01 | 3.6e-03 | 11.4 | 10.9 | 1.6e-27 | 0.82 | 0.10 | 0.72 | FALSE |
| 5 | The Cancer Genome Atlas | Thyroid Carcinoma | VAV3 | 0.09 | 0.02 | enet | 13 | 0.05 | 1.3e-05 | 11.8 | 10.4 | 3.2e-25 | 0.87 | 0.01 | 0.99 | FALSE |