Best TWAS P=1.1e-09 · Best GWAS P=1.21e-10 conditioned to 0.00411
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Nerve Tibial | SPP1 | 0.15 | 0.08 | lasso | 3 | 0.08 | 2.4e-06 | -5.8 | -5.8 | 8.0e-09 | 0.82 | 0.02 | 0.98 | FALSE |
| 2 | The Cancer Genome Atlas | Breast Invasive Carcinoma | SPP1 | 0.04 | 0.00 | enet | 11 | 0.01 | 3.3e-03 | -5.5 | -6.1 | 1.1e-09 | 0.74 | 0.00 | 0.96 | TRUE |