Best TWAS P=6.49e-09 · Best GWAS P=9.63e-12 conditioned to 0.000802
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | ROSMAP | Brain Pre-frontal Cortex | GAL | 0.21 | 0.17 | bslmm | 393 | 0.17 | 1.5e-21 | 4.4 | 5.2 | 1.9e-07 | 0.48 | 1.00 | 0.00 | TRUE |
| 2 | ROSMAP | Brain Pre-frontal Cortex | PPP6R3 | 0.04 | 0.01 | blup | 421 | 0.02 | 3.2e-04 | 6.8 | -5.8 | 6.5e-09 | -0.87 | 0.03 | 0.97 | TRUE |
| 3 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | SAPS3 | 0.04 | 0.02 | blup | 84 | 0.04 | 2.5e-05 | 5.1 | -5.7 | 1.2e-08 | -0.86 | 0.16 | 0.83 | FALSE |