Best TWAS P=4.13e-10 · Best GWAS P=4.21e-07 conditioned to 0.917
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | METSIM | Adipose | IQGAP1 | 0.11 | 0.08 | enet | 32 | 0.12 | 3.9e-17 | -4.0 | -5.7 | 1.3e-08 | 0.85 | 0.06 | 0.90 | FALSE |
| 2 | YFS | Blood | IQGAP1 | 0.18 | 0.17 | enet | 46 | 0.20 | 5.8e-65 | -4.9 | -5.7 | 9.0e-09 | 0.90 | 0.01 | 0.99 | FALSE |
| 3 | The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | IQGAP1 | 0.15 | 0.05 | enet | 10 | 0.08 | 2.5e-09 | -4.6 | -5.5 | 3.3e-08 | 0.87 | 0.01 | 0.98 | FALSE |
| 4 | The Cancer Genome Atlas | Prostate Adenocarcinoma | IQGAP1 | 0.11 | 0.03 | enet | 8 | 0.06 | 1.4e-06 | -4.6 | -6.2 | 4.1e-10 | 0.82 | 0.02 | 0.97 | TRUE |