[Hub]/) : Traits : Hayfever/allergic rhinitis (self-reported) :

chr17:37,363,793-38,783,469

Best TWAS P=1.68e-09 · Best GWAS P=2.26e-09 conditioned to 0.0581

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 CommonMind Brain Pre-frontal Cortex ORMDL3 0.09 0.08 enet 10 0.06 4.2e-08 5.1 5.4 8.0e-08 0.82 0.10 0.90 FALSE
2 GTEx Cells Transformed fibroblasts ORMDL3 0.24 0.09 enet 21 0.07 7.8e-06 5.1 6.0 1.7e-09 0.81 0.01 0.99 TRUE
3 GTEx Lung GSDMB 0.07 0.07 lasso 4 0.05 1.5e-04 5.1 5.3 1.2e-07 0.86 0.03 0.94 FALSE
4 GTEx Lung ORMDL3 0.16 0.13 enet 15 0.14 1.6e-10 5.6 5.9 4.2e-09 0.91 0.01 0.99 FALSE
5 GTEx Spleen ORMDL3 0.40 0.44 enet 11 0.39 5.7e-11 5.1 5.3 1.4e-07 0.91 0.02 0.98 FALSE
6 GTEx Whole Blood GSDMB 0.15 0.10 lasso 4 0.10 4.5e-09 5.6 5.4 7.8e-08 0.92 0.02 0.98 FALSE
7 NTR Blood GSDMB 0.09 0.10 enet 16 0.12 3.8e-36 6.0 5.1 2.8e-07 0.91 0.00 1.00 FALSE
8 The Cancer Genome Atlas Brain Lower Grade Glioma GSDMB 0.06 0.05 enet 7 0.05 2.2e-06 5.3 5.6 2.1e-08 0.91 0.01 0.99 FALSE
9 The Cancer Genome Atlas Lung Adenocarcinoma GSDMB 0.05 0.07 blup 39 0.05 1.4e-06 5.4 5.3 1.1e-07 0.90 0.01 0.99 FALSE
10 The Cancer Genome Atlas Stomach Adenocarcinoma IKZF3 0.03 0.01 blup 43 0.02 1.3e-02 5.5 -5.7 9.4e-09 -0.80 0.01 0.66 FALSE
11 The Cancer Genome Atlas Stomach Adenocarcinoma ZPBP2 0.08 0.09 enet 5 0.10 6.1e-08 5.3 -5.2 1.6e-07 -0.90 0.05 0.94 FALSE
12 The Cancer Genome Atlas Thyroid Carcinoma GSDMB 0.08 0.08 blup 40 0.09 6.6e-09 5.3 5.4 6.1e-08 0.86 0.01 0.99 FALSE
13 The Cancer Genome Atlas Thyroid Carcinoma ORMDL3 0.08 0.13 blup 37 0.15 3.8e-14 5.1 5.2 2.2e-07 0.88 0.02 0.98 FALSE