[Hub]/) : Traits : Gout (self-reported) :

chr7:71,935,903-73,738,067

Best TWAS P=6.13e-12 · Best GWAS P=4.99e-12 conditioned to 1

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous MLXIPL 0.11 0.07 enet 16 0.07 1.6e-06 -6.1 -6.3 3.0e-10 0.93 0.01 0.99 FALSE
2 GTEx Adipose Visceral Omentum MLXIPL 0.16 0.02 lasso 3 0.03 7.8e-03 -6.5 -6.6 5.4e-11 0.93 0.04 0.96 FALSE
3 GTEx Cells Transformed fibroblasts MLXIPL 0.13 0.06 enet 6 0.09 2.2e-07 -6.9 -6.7 2.3e-11 0.93 0.00 0.99 FALSE
4 GTEx Heart Left Ventricle MLXIPL 0.14 0.00 enet 24 0.01 1.3e-01 -2.7 -5.3 1.1e-07 0.59 0.06 0.70 FALSE
5 GTEx Lung MLXIPL 0.10 0.07 enet 14 0.07 6.3e-06 -6.1 -5.3 1.2e-07 0.68 0.03 0.92 FALSE
6 GTEx Skin Not Sun Exposed Suprapubic MLXIPL 0.11 0.11 lasso 3 0.06 2.7e-04 -6.9 -6.9 6.1e-12 0.99 0.00 0.99 TRUE
7 GTEx Skin Sun Exposed Lower leg MLXIPL 0.12 0.09 lasso 4 0.06 6.1e-06 -6.7 -6.8 1.4e-11 0.96 0.01 0.99 FALSE
8 GTEx Spleen NCF1B 0.22 0.10 enet 9 0.08 5.1e-03 -5.1 5.4 5.9e-08 -0.70 0.04 0.29 FALSE
9 GTEx Thyroid MLXIPL 0.23 0.14 lasso 7 0.15 2.1e-11 -6.1 -6.8 1.1e-11 0.95 0.01 0.99 FALSE
10 METSIM Adipose MLXIPL 0.12 0.14 lasso 4 0.13 1.8e-19 -5.9 -6.3 2.9e-10 0.84 0.26 0.74 FALSE
11 The Cancer Genome Atlas Breast Invasive Carcinoma MLXIPL 0.06 0.05 lasso 2 0.05 5.1e-10 -5.8 -5.6 2.1e-08 0.76 0.00 1.00 FALSE
12 The Cancer Genome Atlas Lung Adenocarcinoma MLXIPL 0.04 0.03 lasso 1 0.02 2.3e-03 -5.8 -5.8 6.4e-09 0.76 0.00 0.97 FALSE
13 The Cancer Genome Atlas Prostate Adenocarcinoma MLXIPL 0.08 0.05 enet 4 0.05 5.3e-06 -5.8 -5.5 3.8e-08 0.70 0.00 1.00 FALSE