Best TWAS P=1.08e-16 · Best GWAS P=9.37e-20 conditioned to 0.000146
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Whole Blood | TRIM38 | 0.08 | 0.04 | enet | 13 | 0.03 | 1.4e-03 | -8.3 | -7.5 | 5.3e-14 | 0.87 | 0.23 | 0.71 | FALSE |
2 | GTEx | Whole Blood | U91328.21 | 0.07 | 0.04 | lasso | 4 | 0.04 | 1.7e-04 | -8.3 | -8.3 | 1.1e-16 | 0.94 | 0.13 | 0.67 | TRUE |
3 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | SLC17A1 | 0.08 | 0.06 | lasso | 5 | 0.06 | 1.3e-07 | -5.8 | 6.4 | 1.3e-10 | -0.69 | 0.08 | 0.92 | FALSE |