225 significantly associated models · 62 unique genes
.
# | chr | p0 | p1 | # assoc genes | # joint genes | best TWAS P | best SNP P | cond SNP P | % var exp | joint genes |
---|---|---|---|---|---|---|---|---|---|---|
1 | 2 | 26592429 | 28607344 | 19 | 1 | 6.0e-28 | 3.8e-28 | 1.00000 | 100 | FNDC4 |
2 | 3 | 52174970 | 53623102 | 2 | 1 | 1.8e-09 | 1.6e-10 | 0.02980 | 88 | SFMBT1 |
3 | 4 | 9370814 | 11156010 | 4 | 9 | 3.2e-70 | 2.9e-88 | NaN | NaN | RP11-448G15.3 SLC2A9 WDR1 |
4 | 4 | 87655053 | 89947462 | 7 | 13 | 3.8e-123 | 1.5e-197 | NaN | NaN | ABCG2 HERC6 NUDT9 PKD2 PPM1K RP11-10L7.1 SPP1 |
5 | 5 | 72171715 | 72675238 | 1 | 1 | 1.7e-08 | 1.7e-08 | 1.00000 | 100 | TMEM171 |
6 | 6 | 25266147 | 26689223 | 3 | 1 | 1.1e-16 | 9.4e-20 | 0.00015 | 83 | U91328.21 |
7 | 7 | 71935903 | 73738067 | 2 | 1 | 6.1e-12 | 5.0e-12 | 1.00000 | 100 | MLXIPL |
8 | 10 | 60712592 | 62185494 | 1 | 1 | 4.8e-11 | 6.6e-13 | 0.00367 | 84 | SLC16A9 |
9 | 11 | 63305184 | 66262606 | 7 | 7 | 6.8e-26 | 4.5e-21 | NaN | NaN | CCDC88B NRXN2 OVOL1 SLC22A11 SLC22A12 VEGFB |
10 | 12 | 56776586 | 58705075 | 4 | 1 | 4.6e-13 | 1.2e-14 | 0.00738 | 88 | INHBC |
11 | 12 | 121820692 | 123326374 | 1 | 1 | 5.0e-10 | 1.0e-10 | 1.00000 | 100 | MLXIP |
12 | 15 | 75444033 | 76878362 | 1 | 1 | 6.4e-09 | 1.5e-06 | 0.58700 | 99 | UBE2Q2 |
13 | 15 | 90385311 | 90891982 | 1 | 1 | 1.1e-08 | 1.1e-08 | 1.00000 | 100 | IDH2 |
14 | 16 | 69112398 | 70669292 | 1 | 1 | 2.3e-07 | 6.1e-08 | 0.05250 | 87 | WWP2 |
Trait | chisq ratio | # genes+ | # genes++ | % genes++ | corr | corr P | genes |
---|
study | tissue | # hits | % hits/tests | avg chisq |
---|
study | tissue | # hits | % hits/tests | avg chisq |
---|---|---|---|---|
GTEx | Adipose Visceral Omentum | 8 | 0.393 | 1.6 |
The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | 3 | 0.110 | 1.6 |
GTEx | Adipose Subcutaneous | 9 | 0.258 | 1.5 |
GTEx | Artery Coronary | 4 | 0.338 | 1.5 |
GTEx | Colon Sigmoid | 3 | 0.205 | 1.5 |
GTEx | Colon Transverse | 6 | 0.291 | 1.5 |
GTEx | Esophagus Mucosa | 6 | 0.181 | 1.5 |
GTEx | Esophagus Muscularis | 5 | 0.155 | 1.5 |
GTEx | Liver | 1 | 0.139 | 1.5 |
GTEx | Small Intestine Terminal Ileum | 1 | 0.217 | 1.5 |
GTEx | Vagina | 1 | 0.157 | 1.5 |
GTEx | Whole Blood | 4 | 0.201 | 1.5 |
GTEx | Adrenal Gland | 2 | 0.137 | 1.4 |
GTEx | Artery Aorta | 5 | 0.168 | 1.4 |
GTEx | Artery Tibial | 9 | 0.239 | 1.4 |
GTEx | Brain Cerebellum | 1 | 0.050 | 1.4 |
GTEx | Breast Mammary Tissue | 2 | 0.101 | 1.4 |
GTEx | Breast Mammary Tissue (Female) | 1 | 0.061 | 1.4 |
GTEx | Cells EBV-transformed lymphocytes | 2 | 0.141 | 1.4 |
GTEx | Esophagus Gastroesophageal Junction | 2 | 0.138 | 1.4 |
GTEx | Heart Left Ventricle | 1 | 0.065 | 1.4 |
GTEx | Lung | 5 | 0.174 | 1.4 |
GTEx | Muscle Skeletal | 5 | 0.173 | 1.4 |
GTEx | Nerve Tibial | 9 | 0.208 | 1.4 |
GTEx | Ovary | 1 | 0.110 | 1.4 |
GTEx | Prostate | 1 | 0.120 | 1.4 |
GTEx | Skin Not Sun Exposed Suprapubic | 4 | 0.163 | 1.4 |
GTEx | Skin Sun Exposed Lower leg | 5 | 0.137 | 1.4 |
GTEx | Spleen | 2 | 0.142 | 1.4 |
GTEx | Testis | 5 | 0.158 | 1.4 |
GTEx | Thyroid | 7 | 0.175 | 1.4 |
METSIM | Adipose | 7 | 0.152 | 1.4 |
NTR | Blood | 2 | 0.083 | 1.4 |
ROSMAP | Brain Pre-frontal Cortex | 10 | 0.228 | 1.4 |
The Cancer Genome Atlas | Breast Invasive Carcinoma | 10 | 0.227 | 1.4 |
The Cancer Genome Atlas | Cervical Squamous Cell Carcinoma | 3 | 0.273 | 1.4 |
The Cancer Genome Atlas | Esophageal Carcinoma | 1 | 0.146 | 1.4 |
The Cancer Genome Atlas | Glioblastoma Multiforme | 1 | 0.098 | 1.4 |
The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | 10 | 0.244 | 1.4 |
The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | 3 | 0.146 | 1.4 |
The Cancer Genome Atlas | Liver Hepatocellular Carcinoma | 1 | 0.090 | 1.4 |
The Cancer Genome Atlas | Ovarian Serous Cystadenocarcinoma | 3 | 0.188 | 1.4 |
The Cancer Genome Atlas | Pancreatic Adenocarcinoma | 2 | 0.120 | 1.4 |
The Cancer Genome Atlas | Skin Cutaneous Melanoma | 0 | 0.000 | 1.4 |
The Cancer Genome Atlas | Testicular Germ Cell Tumors | 0 | 0.000 | 1.4 |
The Cancer Genome Atlas | Thyroid Carcinoma | 8 | 0.155 | 1.4 |
GTEx | Brain Cerebellar Hemisphere | 1 | 0.067 | 1.3 |
GTEx | Brain Cortex | 1 | 0.097 | 1.3 |
GTEx | Brain Frontal Cortex BA9 | 0 | 0.000 | 1.3 |
GTEx | Brain Hippocampus | 0 | 0.000 | 1.3 |
GTEx | Brain Hypothalamus | 0 | 0.000 | 1.3 |
GTEx | Brain Nucleus accumbens basal ganglia | 1 | 0.116 | 1.3 |
GTEx | Brain Putamen basal ganglia | 0 | 0.000 | 1.3 |
GTEx | Breast Mammary Tissue (Male) | 2 | 0.168 | 1.3 |
GTEx | Cells Transformed fibroblasts | 6 | 0.143 | 1.3 |
GTEx | Heart Atrial Appendage | 0 | 0.000 | 1.3 |
GTEx | Pancreas | 2 | 0.123 | 1.3 |
GTEx | Pituitary | 1 | 0.090 | 1.3 |
GTEx | Stomach | 0 | 0.000 | 1.3 |
GTEx | Uterus | 0 | 0.000 | 1.3 |
YFS | Blood | 4 | 0.087 | 1.3 |
CommonMind | Brain Pre-frontal Cortex | 7 | 0.130 | 1.3 |
The Cancer Genome Atlas | Bladder Urothelial Carcinoma | 2 | 0.121 | 1.3 |
The Cancer Genome Atlas | Colon Adenocarcinoma | 2 | 0.097 | 1.3 |
The Cancer Genome Atlas | Brain Lower Grade Glioma | 3 | 0.070 | 1.3 |
The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | 0 | 0.000 | 1.3 |
The Cancer Genome Atlas | Pheochromocytoma and Paraganglioma | 0 | 0.000 | 1.3 |
The Cancer Genome Atlas | Prostate Adenocarcinoma | 7 | 0.151 | 1.3 |
The Cancer Genome Atlas | Rectum Adenocarcinoma | 1 | 0.145 | 1.3 |
The Cancer Genome Atlas | Stomach Adenocarcinoma | 2 | 0.119 | 1.3 |
The Cancer Genome Atlas | Uterine Corpus Endometrial Carcinoma | 0 | 0.000 | 1.3 |
GTEx | Brain Caudate basal ganglia | 0 | 0.000 | 1.2 |
The Cancer Genome Atlas | Lung Adenocarcinoma | 2 | 0.068 | 1.2 |
The Cancer Genome Atlas | Soft Tissue Sarcoma | 0 | 0.000 | 1.2 |