TWAS hub - TMED4

#	panel	tissue	h2	h2 se	h2 P	eQTL R2	BLUP R2	ENET R2	BSLMM R2	LASSO R2	eQTL P	BLUP P	ENET P	BSLMM P	LASSO P
1	GTEx	Brain Frontal Cortex BA9	0.2290	0.0796	0.00210	0.131	NA	0.005	NA	0.068	2.5e-04	NA	2.3e-01	NA	7.2e-03
2	GTEx	Brain Hypothalamus	0.3690	0.1170	0.00220	-0.013	NA	-0.010	NA	-0.010	8.8e-01	NA	6.3e-01	NA	6.4e-01
3	GTEx	Nerve Tibial	0.1312	0.0526	0.00120	0.043	NA	0.025	NA	0.038	5.1e-04	NA	6.2e-03	NA	1.1e-03
4	GTEx	Stomach	0.1250	0.0470	0.00280	0.041	NA	0.040	NA	0.035	4.6e-03	NA	5.4e-03	NA	8.2e-03
5	METSIM	Adipose	0.0715	0.0250	0.00026	0.007	0.024	0.010	0.025	0.008	2.3e-02	1.4e-04	1.2e-02	9.0e-05	2.0e-02
6	YFS	Blood	0.1273	0.0219	0.00000	0.118	0.133	0.146	0.118	0.147	1.2e-36	2.4e-41	1.9e-45	1.1e-36	1.3e-45
7	TCGA	Breast Invasive Carcinoma	0.0239	0.0156	0.00170	0.003	0.012	0.009	NA	0.007	8.5e-02	1.3e-03	4.9e-03	NA	1.2e-02
8	TCGA	Kidney Renal Clear Cell Carcinoma	0.0253	0.0156	0.00110	0.009	0.012	0.003	NA	0.009	3.1e-02	1.4e-02	1.4e-01	NA	2.9e-02
9	TCGA	Brain Lower Grade Glioma	0.0270	0.0196	0.00530	0.006	0.011	0.016	NA	0.013	6.9e-02	1.6e-02	5.1e-03	NA	1.1e-02

Trait	Avg chi2 ratio	Avg chi2	Max chi2	1	2	3	4	5	6	7	8	9
High cholesterol (Self-reported)	5.9	10.5	34.8	3.9	-0.8	3.3	0.1	1.2	5.9	2.4	4.0	3.1
LDL Cholesterol	5.4	8.5	28.8	3.5	-2.0	2.9	-1.2	1.1	5.4	0.5	3.7	2.6
Pack years of smoking	5.4	7.9	16.2	-2.5	1.5	-3.0	1.6	-2.3	-4.0	-3.2	-3.4	-2.7
Pack years adult smoking proportion	5.1	7.7	16.2	-2.4	1.4	-2.9	1.6	-2.2	-4.0	-3.4	-3.3	-2.7
Cholesterol lowering medication	4.5	6.7	16.2	3.4	0.3	3.2	0.3	1.5	4.0	1.5	3.4	2.5
Hypothyroidism (self reported)	4.4	10.1	22.6	4.4	0.1	4.8	1.4	1.7	3.6	1.2	4.4	3.2
Medication: Levothyroxine sodium	4.4	7.5	15.1	3.8	1.1	3.9	1.8	1.6	3.2	1.3	3.9	2.0
Schizophrenia (2014)	4.3	9.5	22.0	-4.7	-1.0	-4.5	-0.8	0.2	-3.1	-1.1	-4.4	-3.3
Heart disease (siblings)	4.1	5.0	9.4	2.9	0.6	3.1	-1.9	-0.9	2.6	1.8	2.8	2.1
Triglycerides	4.0	6.5	12.0	3.2	-0.0	3.4	-1.2	1.2	3.3	1.5	3.5	3.0
Current tobacco smoking	3.9	6.4	10.8	-2.6	1.8	-2.7	3.3	-0.2	-2.9	-3.0	-2.9	-2.1
Medication: Co-codamol	3.8	4.4	9.4	2.2	2.8	3.1	0.5	2.4	0.5	1.5	2.3	1.9
Supplements: Fish oil (including cod liver oil)	3.8	5.0	10.2	3.2	-0.3	3.2	-0.4	1.1	2.8	1.0	3.0	2.3
Hypothyroidism/myxoedema (self-reported)	3.7	7.1	14.7	3.7	0.4	3.8	1.3	1.3	3.1	1.1	3.8	2.7
Intelligence (Savage-Jansen 2018)	3.6	11.0	22.5	3.7	-2.7	3.5	-0.6	0.5	4.7	2.3	4.3	4.3
Lung cancer (father)	3.6	4.2	8.3	-2.9	1.6	-2.7	0.5	0.1	-2.6	0.2	-2.8	-2.2
Mouth/teeth dental problems	3.5	5.4	12.2	3.3	-1.5	3.5	-1.2	0.3	2.5	0.3	3.0	2.4
Fluid intelligence score	3.3	6.9	12.8	2.6	-2.3	3.1	0.1	0.6	3.6	2.9	3.3	2.9
Eye problems/disorders: Cataract	3.2	3.7	9.2	3.0	1.1	2.7	0.6	1.2	1.8	0.2	2.7	1.8
Noisy workplace	3.1	3.9	7.1	-2.6	1.9	-2.4	-0.7	0.2	-2.5	-0.4	-2.7	-2.2
Waist circumference	3.0	10.9	18.7	4.3	3.5	4.2	3.3	1.4	2.3	1.2	4.0	3.9
Mineral and other dietary supplements	3.0	4.0	7.8	-2.8	-0.2	-2.7	1.6	-1.4	-2.5	-1.1	-2.7	-1.5
Hearing aid user	3.0	3.4	6.7	-1.9	2.6	-1.4	0.6	-2.0	-2.1	-0.7	-2.1	-2.1
Schizophrenia (2018)	2.9	6.0	13.7	-3.7	-0.9	-3.6	-1.1	0.3	-2.3	-1.0	-3.4	-2.7
Hayfever/allergic rhinitis (self-reported)	2.8	3.7	9.1	2.1	-0.1	2.2	3.0	1.9	1.1	0.7	2.3	2.0
Pulse rate	2.8	4.7	8.9	3.0	-0.5	2.4	1.3	2.0	2.4	1.4	2.8	2.4
Illnesses of father: Heart disease	2.8	3.9	8.5	2.9	-1.6	2.3	-1.1	-0.4	2.7	0.2	2.4	2.0
Smoking status: Current	2.7	4.3	10.3	-1.8	1.5	-1.9	3.2	0.0	-2.2	-2.7	-2.1	-1.6
Chronic bronchitis/emphysema (father)	2.5	3.0	6.7	-1.9	2.6	-1.9	2.1	0.3	-1.7	-0.1	-1.7	-1.5
Heart disease (mother)	2.4	3.0	6.8	2.4	1.1	2.6	0.1	1.7	2.0	0.8	2.0	1.0
Blood Platelet Count	2.3	27.0	141.6	-2.8	11.9	-2.8	0.2	-3.0	-5.8	-3.0	-4.4	-3.9
Long-standing illness, disability or infirmity	2.3	3.5	7.8	2.8	2.6	2.3	1.7	0.3	0.8	-0.7	2.2	1.6
Osteoarthritis (self-reported)	2.3	2.9	6.0	2.1	0.7	2.0	0.7	0.9	2.0	1.5	2.5	1.9
Number of operations (self-reported)	2.3	3.5	7.1	2.2	-0.5	1.9	-0.4	1.0	2.5	2.0	2.7	2.0
Bipolar Disorder or Schizophrenia	2.2	5.5	12.0	-3.5	-1.1	-3.2	-1.8	-0.3	-2.5	-0.3	-3.2	-2.5
Age at First Birth	2.2	3.2	18.4	0.9	-4.3	0.6	-1.4	0.7	1.4	1.1	1.4	1.4
Had menopause	2.2	2.7	5.3	1.7	-0.8	2.0	-1.3	1.0	2.0	0.9	2.0	2.3
Hip circumference	2.2	9.4	19.1	3.7	2.1	3.8	2.4	0.1	2.6	2.4	4.0	4.4
Qualifications: NVQ or HND or HNC or equivalent	2.2	2.6	7.3	-1.4	2.7	-1.1	-1.6	-1.2	-1.4	-0.8	-1.5	-2.1
Schizophrenia vs Biploar Disorder	2.1	2.8	5.5	-2.3	0.4	-2.3	1.3	0.9	-1.4	-0.5	-2.3	-1.9
Type 2 Diabetes (T2D) (2012)	2.1	2.4	14.5	1.0	3.8	0.6	1.3	0.2	-1.5	-1.1	-0.0	-0.7
Allergy or Eczema	2.1	5.6	13.2	3.6	1.2	2.9	1.6	2.2	1.5	-0.6	3.1	2.8
Hayfever, allergic rhinitis or eczema	2.1	4.6	11.3	3.4	1.3	2.8	0.9	1.9	1.2	-0.1	3.0	2.4
Whole body fat mass	2.1	8.6	14.0	3.7	3.5	3.5	3.4	0.0	2.2	1.0	3.5	3.1
Arm fat mass (left)	2.1	8.4	13.6	3.6	3.7	3.4	3.0	0.3	2.1	1.3	3.5	3.2
Leg fat percentage (left)	2.1	7.5	17.8	3.4	4.2	3.2	2.7	0.6	1.7	0.9	3.0	2.7
Medication: Omeprazole (e.g. Zanprol)	2.1	2.6	15.2	0.5	1.6	0.9	3.9	0.9	0.4	1.0	0.6	1.6
Leg fat mass (left)	2.1	8.3	14.8	3.6	3.9	3.4	3.0	0.3	1.9	1.2	3.4	3.3
Other serious medical condition/disability diagnosed by doctor	2.0	2.6	8.8	3.0	0.5	2.2	0.9	0.8	1.6	-1.6	1.8	0.2
Medication: Omeprazole	2.0	2.4	13.4	1.3	1.4	1.6	3.7	0.3	0.3	0.0	0.9	1.2
Ever had stillbirth, spontaneous miscarriage or termination	2.0	2.1	7.9	0.8	-2.1	0.8	-2.8	-2.0	0.5	0.5	1.0	0.4
Heart attack/myocardial infarction (self-reported)	2.0	2.5	7.4	2.7	1.4	2.1	-0.4	-0.6	1.7	0.0	2.0	1.2
Verbal and Numeric Reasoning (VNR)	1.9	4.5	10.4	2.0	-2.2	2.1	-0.0	0.2	3.2	2.7	2.5	1.8
Blood Red Count	1.9	18.0	63.0	-3.9	7.9	-4.0	-1.1	-2.7	-3.9	-2.0	-4.4	-4.6
Supplements: Glucosamine	1.9	2.5	6.9	1.8	-1.1	1.5	-1.0	1.8	2.6	0.8	1.8	0.6
Qualifications: None of the above	1.9	4.1	7.0	-1.5	2.6	-2.0	2.2	-0.9	-2.4	-2.2	-2.3	-1.5
Heart attack	1.9	2.4	6.8	2.6	1.4	2.0	-0.5	-0.3	1.7	0.1	1.9	1.1
Leg fat mass (right)	1.9	7.4	14.1	3.4	3.8	3.2	3.1	0.0	1.6	0.8	3.1	2.9
Friendships satisfaction	1.9	2.4	6.1	-0.1	-2.5	0.8	0.1	0.8	1.7	2.4	1.2	2.0
Back pain experienced in last month	1.9	2.7	7.1	1.5	1.4	2.1	-2.7	0.8	0.7	1.4	1.6	1.8
Guilty feelings	1.9	2.9	5.1	-2.1	-1.6	-2.2	-1.2	0.2	-1.4	-0.7	-2.3	-2.2
Cardiovascular Disease	1.8	6.0	16.2	3.7	1.0	2.8	1.8	0.2	4.0	0.4	3.0	1.8
Number of treatments/medications taken	1.8	3.2	6.9	2.5	2.2	2.6	1.6	0.2	1.7	-0.1	2.0	1.1
Had other major operations	1.8	2.2	4.4	1.8	-0.7	1.4	0.6	1.5	2.1	0.9	2.0	1.4
Arm fat mass (right)	1.8	7.5	12.0	3.4	3.5	3.2	2.9	0.0	1.9	1.2	3.2	3.1
Headache pain in last month	1.8	3.0	7.9	-1.1	0.4	-1.4	-1.1	-1.1	-2.8	-2.3	-1.8	-2.2
Body fat percentage	1.8	7.3	14.9	3.2	3.9	2.8	3.7	0.8	1.7	0.8	2.8	2.5
Leg fat percentage (right)	1.8	6.4	16.9	3.1	4.1	2.8	3.1	0.4	1.4	0.4	2.6	2.2
Medication: Allopurinol	1.8	2.5	4.6	-1.1	0.5	-2.1	-0.9	-1.6	-1.6	-2.0	-1.9	-1.7
Mood swings	1.8	3.2	5.8	-1.7	-1.1	-2.3	0.1	-0.8	-2.0	-2.4	-2.1	-2.3
Ever used hormone-replacement therapy (HRT)	1.7	2.2	3.8	1.7	-1.3	1.9	-0.4	0.9	1.9	1.2	2.0	1.4
Body mass index (BMI)	1.7	7.1	18.6	3.2	4.3	3.1	2.1	-0.1	1.3	1.3	3.0	2.9
Trunk fat mass	1.7	7.5	13.2	3.4	3.6	3.0	3.4	0.1	1.9	0.8	3.1	2.8
Weight	1.7	8.1	13.5	3.5	3.1	3.5	2.3	-0.2	2.0	1.7	3.7	3.6
Seen a psychiatrist for nerves, anxiety, tension or depression	1.7	2.2	6.0	2.4	0.9	1.2	1.6	1.6	0.9	-1.4	1.7	0.9
Arm fat percentage (left)	1.7	6.8	13.5	3.1	3.7	2.7	3.4	0.4	1.8	1.0	2.8	2.6
Number of self-reported non-cancer illnesses	1.7	3.0	8.7	2.9	1.5	2.5	1.2	0.3	1.6	-0.7	2.0	0.7
Reaction Time	1.6	3.1	8.2	2.0	1.7	1.8	1.3	2.9	1.1	0.5	1.8	1.6
Prostate Cancer	1.6	2.2	5.7	-1.3	0.2	-1.7	1.1	0.5	-2.4	-1.4	-2.0	-1.6
Fasting Glucose	1.6	1.9	3.9	1.7	2.0	1.0	-1.1	-1.8	-0.6	-1.8	0.3	-0.9
Trunk fat percentage	1.6	6.3	13.9	3.0	3.7	2.5	3.6	0.7	1.6	0.5	2.5	2.2
High blood pressure	1.6	4.4	11.9	3.5	1.2	2.8	0.6	0.1	2.9	0.2	2.8	1.6
Allergy	1.6	3.7	8.8	-3.0	-2.0	-2.6	-1.4	-1.6	-0.8	-0.1	-2.4	-1.6
Time employed in main current job	1.6	1.8	8.3	-0.7	0.1	-0.8	-1.9	-2.9	-0.7	-1.2	-1.0	-0.6
Father’s age at death	1.6	2.1	3.9	-1.9	-1.9	-2.0	-1.8	-0.6	-1.1	0.1	-1.3	-1.0
Chronic bronchitis/emphysema (mother)	1.6	1.9	3.9	-1.0	0.3	-0.8	0.9	-1.9	-2.0	-1.3	-1.4	-1.8
Worry too long after embarrassment	1.6	2.6	7.3	-0.6	-1.3	-1.2	-2.7	-1.2	-1.5	-1.9	-1.5	-1.8
Chest pain or discomfort	1.6	2.4	8.4	1.1	1.2	1.1	0.6	1.4	1.7	1.1	1.6	2.9
Leg pain on walking	1.6	2.0	4.0	1.4	1.3	1.6	1.2	1.8	0.5	1.2	1.3	2.0
Medication: Atorvastatin	1.6	2.0	5.7	1.2	-1.0	1.5	-0.8	0.9	2.4	1.5	1.4	1.4
Worrier / anxious feelings	1.5	2.9	5.1	-1.2	-0.8	-1.6	-1.8	-2.3	-1.5	-2.1	-1.8	-1.8
Falls in the last year	1.5	2.0	4.5	-1.2	1.3	-1.1	-0.8	-1.0	-2.1	-1.7	-1.9	-1.0
Happiness	1.5	1.8	6.2	0.2	-1.5	0.9	0.3	0.9	1.6	2.5	1.1	1.4
Exposure to tobacco smoke outside home	1.5	2.0	5.4	-0.6	2.3	-1.1	-1.4	-0.9	-1.7	-1.5	-1.1	-1.4
Mouth/teeth dental problems: Mouth ulcers	1.5	2.5	4.7	-2.2	1.8	-2.0	-1.3	-0.7	-1.8	0.1	-1.8	-1.4
Ever taken oral contraceptive pill	1.5	1.7	3.7	1.4	-1.0	0.9	1.9	1.7	1.4	0.4	1.4	0.8
Eye problems/disorders: Glaucoma	1.5	1.8	4.8	-1.9	0.9	-1.4	-1.2	-0.0	-2.2	0.1	-1.7	-0.5
Vascular/heart problems diagnosed by doctor	1.5	4.2	11.4	-3.4	-1.2	-2.7	-0.7	0.1	-2.8	-0.2	-2.7	-1.6
Depression (Nagel 2018)	1.4	2.1	4.0	-1.3	0.2	-1.7	1.2	-0.3	-1.8	-1.2	-1.9	-2.0
Neuroticism (Nagel 2018)	1.4	3.2	5.8	-2.1	-1.9	-2.3	-0.9	-0.8	-1.7	-0.9	-2.2	-2.4
Neuroticism (2016)	1.4	2.1	6.2	-1.4	-2.5	-1.6	-2.0	-1.2	-0.0	-0.7	-1.0	-1.1
Blood Eosinophil Count	1.4	10.7	61.8	1.3	5.0	1.0	7.9	1.7	1.0	0.2	1.0	1.3
Blood White Count	1.4	10.1	37.0	-2.2	6.1	-2.4	2.9	-1.4	-3.1	-2.3	-3.2	-2.7
Alcohol usually taken with meals	1.4	2.3	9.4	0.3	-3.1	0.8	-1.5	0.7	1.7	2.1	1.1	0.0
Tense / ‘highly strung’	1.4	2.3	9.4	-0.3	-3.1	-0.7	-1.7	-2.3	-0.3	-1.3	-0.5	-0.8
Seen doctor (GP) for nerves, anxiety, tension or depression	1.4	2.2	4.2	-1.3	-1.9	-1.7	-0.3	-0.5	-1.7	-1.3	-1.6	-2.0
Mouth/teeth dental problems: Bleeding gums	1.4	1.8	4.6	-1.8	0.3	-2.1	0.8	-0.6	-1.3	-0.4	-1.8	-1.5
Pulse wave peak to peak time	1.4	1.6	2.4	-1.6	1.4	-1.5	1.0	-1.0	-1.5	0.3	-1.3	-1.2
Medication: Seretide 50 evohaler	1.4	1.6	6.7	1.7	-0.4	0.9	1.6	0.1	-0.2	-2.6	0.5	-1.1
Medication: Gliclazide	1.4	1.6	5.2	-0.5	1.1	-0.9	0.4	-2.3	-1.2	-1.3	-1.4	-1.3
Risk taking	1.4	2.1	4.3	-1.4	-0.8	-1.6	-1.1	-0.2	-2.0	-1.2	-1.7	-2.1
Ever depressed for a whole week	1.4	1.7	3.5	-1.4	-1.9	-1.4	-1.5	-1.5	-1.2	0.1	-1.2	-1.0
Basal cell carcinoma (self-reported)	1.4	1.6	11.1	0.5	-1.2	0.4	-3.3	0.1	0.6	0.3	0.4	1.1
Worry (Nagel 2018)	1.3	2.8	6.4	-1.6	-2.5	-1.7	-1.6	-1.6	-1.0	-0.5	-1.5	-2.0
Alzheimer’s Disease (in mother)	1.3	1.6	3.9	-1.5	0.5	-1.5	-0.5	-1.1	-0.9	-0.6	-1.7	-2.0
BMI	1.3	7.7	22.5	2.8	4.7	3.0	3.8	-0.4	0.8	1.4	2.5	2.6
Arm fat percentage (right)	1.3	5.2	12.2	2.6	3.5	2.2	3.4	0.1	1.2	0.7	2.2	2.0
Illnesses of mother	1.3	1.6	7.7	0.7	-0.9	0.8	-0.3	0.6	0.8	1.2	1.5	2.8
Medication for cholesterol, blood pressure or diabetes	1.3	2.1	4.6	-2.1	-2.0	-1.5	-1.1	-0.1	-2.1	0.6	-1.4	-0.6
Emphysema/chronic bronchitis	1.3	1.5	3.6	-0.9	1.0	-0.7	1.0	-1.0	-1.9	-1.4	-1.3	-1.4
Angina (self-reported)	1.3	1.7	3.5	1.9	0.5	1.5	-1.5	0.7	1.3	0.4	1.7	1.1
Hypertension (Self-reported)	1.3	3.5	9.7	3.1	1.1	2.6	0.5	-0.2	2.5	0.0	2.4	1.4
Mother’s age at death	1.3	1.6	4.0	-1.9	-1.2	-2.0	-1.5	-0.6	-0.0	0.5	-1.4	-0.7
Medication: Paracetamol	1.3	2.1	4.8	-1.1	1.8	-0.9	-1.2	-1.9	-2.2	-0.6	-1.2	-1.2
Unable to work because of sickness or disability	1.3	1.7	3.9	-0.6	0.2	-1.5	1.3	-0.4	-1.7	-1.6	-1.3	-2.0
Medication: Simvastatin	1.2	1.8	4.8	2.2	1.4	1.5	-0.3	-0.4	1.8	-0.4	1.4	1.4
Neuroticism score	1.2	2.6	4.2	-1.6	-1.9	-2.0	-0.8	-1.8	-1.1	-1.8	-1.6	-1.6
Qualifications: A levels/AS levels or equivalent	1.2	2.7	19.5	0.1	-4.4	0.1	-1.8	-0.8	1.0	0.4	0.4	-0.1
Medication: Cholesterol lowering	1.2	1.9	5.2	2.2	1.2	1.4	-0.6	0.1	2.3	-0.6	1.5	0.7
Gout (self-reported)	1.2	1.7	5.4	-1.6	0.1	-2.3	-0.5	-0.6	-1.3	-0.5	-1.8	-1.2
Medication: Ibuprofen	1.2	1.5	7.4	-0.7	1.0	-0.7	-2.7	-1.5	-0.6	0.4	-0.7	-0.8
Overall health rating	1.2	2.7	5.8	2.3	0.6	1.8	0.4	1.9	1.2	0.3	2.0	2.4
Commuting to job workplace: Car/motor vehicle	1.2	1.4	6.4	0.0	1.1	-0.2	2.5	0.1	-0.9	-1.4	-0.6	-1.4
Arm predicted mass (left)	1.2	6.2	13.5	3.1	1.7	3.3	0.4	-0.5	2.0	1.7	3.5	3.7
Breast Cancer	1.1	2.6	4.8	-1.3	0.5	-1.9	-0.5	0.2	-2.2	-2.1	-2.0	-2.1
Waist Hip Ratio (WHR)	1.1	5.2	11.7	3.0	0.8	2.5	2.2	3.4	2.3	-0.4	2.5	1.4
Taking other prescription medications	1.1	1.6	4.3	1.7	1.1	2.0	2.1	0.5	0.7	-0.2	1.1	0.6
Tinnitus: Yes, but not now, but have in the past	1.1	1.2	3.2	-0.1	1.3	-1.2	-0.7	-1.3	-0.8	-1.8	-1.0	-0.5
Medication: Ibuprofen (e.g. Nurofen)	1.1	1.4	5.6	-0.9	0.9	-0.9	-2.4	-1.1	-1.0	0.2	-0.9	-1.3
Pulse wave Arterial Stiffness index	1.1	1.3	2.1	1.4	-1.3	1.4	-0.9	1.1	1.2	-0.5	1.1	0.9
Medication: Paracetamol	1.1	1.8	4.4	-1.0	1.3	-0.9	-1.2	-1.8	-2.1	-0.6	-1.2	-1.3
Arm fat-free mass (right)	1.1	5.8	12.6	2.9	1.8	3.2	0.1	-0.7	1.8	1.8	3.3	3.5
Wheeze or whistling in the chest in last year	1.1	2.0	11.8	-0.5	2.0	-0.6	3.4	0.6	-0.8	-0.3	-0.6	-0.7
Mean time to correctly identify matches	1.1	2.1	6.2	1.6	2.1	1.1	1.1	2.5	0.8	-0.1	1.2	1.1
Arm predicted mass (right)	1.1	5.6	12.7	2.8	1.8	3.1	0.3	-0.6	1.8	1.6	3.3	3.6
Gastro-oesophageal reflux (gord) / gastric reflux (Self-reported)	1.1	1.3	3.0	1.4	0.4	1.7	1.7	0.4	0.7	-0.1	1.3	1.0
Forced expiratory volume in 1-second (FEV1), predicted percentage	1.1	2.2	10.2	-0.5	1.3	0.2	-3.2	-1.5	-0.2	1.9	0.2	1.5
Average weekly champagne plus white wine intake	1.1	1.5	6.6	1.1	-2.6	1.0	-0.3	0.7	1.2	0.4	1.4	0.6
Arm fat-free mass (left)	1.1	5.6	11.5	2.9	1.7	3.2	0.3	-0.4	1.8	1.6	3.3	3.4
Crohns Disease (2017)	1.0	2.3	4.6	-2.1	-1.5	-1.8	-1.6	-0.4	-0.7	0.4	-1.9	-1.8
Mean Putamen Volume	1.0	1.2	2.3	1.4	-0.8	1.4	1.2	1.5	0.6	-0.2	1.3	0.5
Respiratory disease	1.0	2.3	11.7	1.9	0.7	1.5	3.4	0.2	0.5	-0.8	1.3	-0.0
Neuroticism	1.0	2.5	5.9	-2.2	-1.4	-2.4	-0.9	-1.4	-1.2	-0.6	-1.8	-1.3
Angina	1.0	1.3	2.7	1.7	0.6	1.2	-1.5	0.6	1.1	0.3	1.5	1.0
Medication for hormone replacement therapy	1.0	1.1	2.6	-1.0	-1.6	-1.4	0.0	-0.7	-0.4	-0.7	-1.1	-1.4
Impedance of arm (right)	1.0	4.6	9.6	-2.3	-1.7	-2.8	2.1	1.0	-1.0	-1.5	-2.6	-3.1
Asthma	1.0	2.0	5.8	2.4	1.1	1.8	1.9	-0.5	0.2	-1.4	1.6	-0.1
Loud music exposure frequency	1.0	1.1	2.6	-1.4	0.4	-1.6	0.1	-0.0	-1.5	-0.8	-1.5	-0.5
Number of children fathered	1.0	1.1	2.8	1.4	-0.9	1.4	-1.7	-0.7	0.2	-0.2	1.1	0.5
Pulse rate, automated reading	1.0	3.4	10.7	3.3	-0.9	2.4	0.3	0.9	1.5	-0.5	2.6	1.8
Number of full sisters	1.0	1.3	3.3	1.6	1.8	1.3	0.3	1.4	0.6	0.2	1.2	0.3
Age at last live birth	1.0	1.5	4.7	-1.0	-1.6	-1.4	-1.4	-2.2	-0.6	-0.1	-1.0	-0.4
Family relationship satisfaction	1.0	1.2	4.9	-1.1	-0.5	-0.7	1.3	1.3	-0.0	2.2	-0.4	-0.2
Illness, injury, bereavement, stress in last 2 years	1.0	1.2	4.4	0.6	-0.8	0.5	2.1	1.3	1.1	0.2	0.8	1.2
Illnesses of siblings: Diabetes	1.0	1.2	4.1	1.2	2.0	1.2	0.4	1.4	0.2	1.0	0.8	0.1
Diabetes diagnosed by doctor	1.0	1.7	8.4	-0.4	2.9	-0.8	-1.4	-1.3	-1.2	-0.3	-0.7	-0.3
Commuting to job workplace: Walk	1.0	1.0	3.0	-1.6	-0.6	-1.3	-0.8	0.4	0.4	1.7	-0.7	-0.5
Asthma (self-reported)	1.0	1.9	5.3	2.3	1.3	1.6	1.9	0.1	0.3	-1.3	1.5	-0.2
Alcohol drinker status: Never	1.0	1.1	4.2	-0.1	1.3	0.1	-1.9	-2.1	-0.5	-0.2	-0.3	0.4
Diastolic blood pressure, automated reading	1.0	3.1	7.1	2.7	2.3	2.2	1.8	0.3	0.8	-0.4	2.0	1.6
Body Mass Index (BMI) (2010)	0.9	1.3	8.0	0.2	1.0	0.0	2.8	0.6	0.2	0.0	0.4	1.4
Primary Biliary Cirrhosis	0.9	1.3	3.7	-1.3	0.0	-1.3	1.9	-0.4	-0.7	-0.7	-1.1	-1.5
Average weekly fortified wine intake	0.9	1.0	2.7	1.1	-1.6	1.0	-0.8	-0.8	1.3	-0.3	1.0	-0.4
Frequency of unenthusiasm / disinterest in last 2 weeks	0.9	1.2	4.7	-0.4	0.5	-0.7	2.2	-0.4	-1.1	-1.1	-0.8	-1.4
Heel bone mineral density (BMD) T-score, automated (left)	0.9	1.9	4.5	-1.2	2.1	-1.1	1.9	0.4	-1.4	-0.2	-1.4	-1.7
Frequency of tenseness / restlessness in last 2 weeks	0.9	1.4	3.0	-0.6	-0.9	-0.9	0.3	-1.7	-1.0	-1.7	-1.2	-1.3
Number of live births	0.9	1.3	2.1	1.0	-0.6	1.4	0.1	1.4	1.2	0.7	1.3	1.5
Prospective memory result	0.9	1.1	2.3	-0.9	-0.4	-1.5	-0.5	0.6	-1.2	-1.1	-1.2	-1.4
Medication: Amlodipine	0.9	1.3	3.1	0.8	0.6	1.3	0.5	1.1	1.3	1.2	1.3	1.8
Smoking status: Previous	0.9	1.3	4.1	1.0	-0.2	1.1	0.5	-0.4	2.0	1.3	1.4	1.1
Illnesses of father: High blood pressure	0.9	1.1	3.8	0.4	0.7	0.2	1.9	1.5	1.1	1.0	0.7	0.6
Basal metabolic rate	0.9	5.0	10.6	2.6	1.7	2.8	0.7	-1.0	1.7	1.9	3.1	3.3
Commuting to job workplace: Cycle	0.9	1.1	3.8	0.0	-1.2	-0.1	-1.9	0.6	1.0	1.6	0.4	1.0
Supplements: Calcium	0.9	0.9	4.9	0.8	-0.2	0.7	0.9	2.2	0.8	0.3	0.6	-0.8
Coronary Artery Disease (CAD)	0.8	1.0	3.0	0.5	-0.7	0.7	-0.7	-0.2	1.7	1.3	1.0	1.2
HbA1C	0.8	0.8	2.5	1.1	1.6	0.8	-1.3	-0.4	-0.3	-1.1	0.4	-0.2
Rheumatoid Arthritis	0.8	1.0	3.2	-0.8	0.3	-1.2	1.1	-0.5	-1.0	-1.8	-1.0	-0.7
Smoking Status	0.8	1.9	4.9	-1.7	1.8	-1.4	2.2	-0.4	-0.8	-0.6	-1.5	-0.8
Chronotype (morning person)	0.8	1.9	5.7	-0.2	-0.3	-0.9	-2.0	-0.8	-1.5	-1.4	-1.1	-2.4
Hand grip strength (right)	0.8	2.3	5.4	1.0	0.8	1.6	-0.0	0.6	1.4	2.3	1.9	2.2
Nervous feelings	0.8	1.5	11.6	-0.4	-3.4	-0.3	-0.3	-0.3	1.0	0.7	0.2	0.5
Diabetes (self-reported)	0.8	1.2	4.2	-0.3	2.0	-0.6	-1.1	-1.6	-1.4	-0.4	-0.7	-0.1
Serious illness, injury or assault of a close relative in last 2 years	0.8	0.9	3.2	0.4	-1.6	-0.0	-1.8	-0.6	1.0	0.4	0.7	0.4
Length of working week for main job	0.8	0.9	5.0	-0.1	-0.4	-0.9	-0.2	-2.2	-0.3	-1.1	-0.5	-0.4
Qualifications: O levels/GCSEs or equivalent	0.8	1.3	4.6	0.8	-2.1	0.8	-1.0	0.4	1.2	0.9	1.1	0.9
Reason for reducing amount of alcohol drunk: Health precaution	0.8	0.9	3.4	0.6	-0.2	0.3	-1.9	-1.5	-0.4	-1.3	-0.1	-0.6
Qualifications: College or University degree	0.8	2.4	13.3	0.3	-3.6	0.2	-2.3	-0.9	0.9	0.7	0.7	0.2
Medication for pain relief, constipation, heartburn	0.8	1.4	7.1	0.3	-2.7	-0.2	-0.4	1.0	1.9	0.0	0.5	0.5
Leg fat-free mass (right)	0.8	4.1	9.1	2.2	1.4	2.4	0.2	-1.1	1.5	2.1	2.7	3.0
Loneliness, isolation	0.8	1.2	2.9	-1.7	-0.5	-1.4	0.8	1.4	-0.7	1.2	-1.0	-0.2
Medication: Laxatives (e.g. Dulcolax, Senokot)	0.8	0.9	2.0	1.1	1.3	1.4	-0.4	0.8	-0.8	0.2	1.0	0.9
Leg predicted mass (right)	0.8	4.0	8.9	2.1	1.4	2.3	0.3	-1.1	1.5	2.2	2.7	3.0
Wears glasses or contact lenses	0.8	0.9	1.8	1.1	-0.0	1.4	0.9	0.9	1.0	0.7	1.1	1.0
Hand grip strength (left)	0.7	1.8	6.0	0.4	0.5	1.0	0.3	0.6	1.3	2.4	1.5	2.2
Frequency of depressed mood in last 2 weeks	0.7	1.0	2.9	-0.7	-1.2	-1.3	1.7	0.2	-0.3	-0.9	-0.8	-0.9
Diabetes (father)	0.7	0.9	2.9	0.3	0.5	-0.6	1.6	0.7	-0.3	-1.7	-0.5	-0.9
Leg fat-free mass (left)	0.7	3.5	6.8	2.1	1.6	2.2	0.8	-1.2	1.3	1.8	2.5	2.6
Townsend deprivation index at recruitment	0.7	1.0	4.1	-0.5	2.0	-0.4	1.8	0.1	-0.7	0.3	-0.5	0.2
Age when periods started (menarche)	0.7	1.7	4.6	0.5	-1.5	0.6	-1.1	-2.1	1.1	0.9	1.0	2.0
Qualifications: CSEs or equivalent	0.7	1.0	2.1	-1.3	1.5	-1.2	0.7	1.0	-0.1	0.8	-1.2	-0.4
Multivitamins +/- minerals	0.7	0.8	3.2	0.6	-1.8	0.3	-0.4	-1.3	0.2	-1.4	0.3	-0.4
Diverticular disease/diverticulitis (self-reported)	0.7	0.9	3.1	-0.0	0.6	-0.7	1.2	-0.6	-1.1	-1.8	-0.8	-0.2
Medication: Atenolol	0.7	0.9	1.7	1.0	0.9	1.1	-0.7	-0.0	1.0	0.4	1.3	1.2
Past tobacco smoking	0.7	1.3	4.3	-0.9	0.3	-0.9	-1.7	-0.2	-2.1	-0.7	-1.2	-0.8
Hearing difficulty/problems with background noise	0.7	1.1	4.8	0.0	-2.2	0.2	0.5	0.3	1.6	1.4	0.4	0.2
Medication: Ventolin 100micrograms inhaler	0.7	0.9	3.2	0.3	-0.3	-0.2	0.8	0.8	-0.7	-1.6	-0.5	-1.8
Age at first live birth	0.7	1.2	5.5	-0.5	-2.4	-0.8	-1.3	-1.3	-0.3	-0.5	-0.6	-0.6
Mouth/teeth dental problems: Loose teeth	0.7	0.9	3.4	-0.3	0.3	-1.0	1.8	0.6	-0.8	-1.1	-0.9	-0.5
Reproduciblity of spirometry measurement using ERS/ATS criteria	0.7	0.9	2.6	-1.6	-0.5	-1.1	0.5	-0.6	-0.5	-0.1	-1.3	-1.1
Suffer from ‘nerves’	0.7	1.2	8.4	-0.4	-2.9	-0.6	0.1	-0.6	0.2	-0.7	-0.2	-0.9
Whole body fat-free mass	0.7	3.9	8.9	2.1	1.1	2.5	-0.0	-1.3	1.5	1.8	2.8	3.0
Handedness (chirality/laterality): Left-handed	0.7	0.9	2.6	-0.7	-0.5	-0.5	-0.5	-1.2	-0.7	-1.2	-0.8	-1.6
Medication for cholesterol	0.7	1.1	3.7	-1.6	0.5	-1.0	0.3	0.5	-1.9	0.4	-1.3	-0.4
Whole body water mass	0.7	4.2	9.2	2.3	1.1	2.6	0.2	-1.2	1.6	1.8	2.9	3.0
Tinnitus: Yes, now most or all of the time	0.7	0.8	2.5	-0.6	1.4	-0.6	0.7	0.0	-1.0	-0.0	-0.6	-1.6
Medication: Bendroflumethiazide	0.7	1.0	5.5	0.7	2.3	0.7	1.5	0.2	0.0	-0.3	0.4	0.3
Alzheimer’s Disease (including proxy)	0.6	0.9	2.3	-1.0	-0.1	-0.8	-1.3	-0.5	-0.7	-0.5	-1.2	-1.5
Systolic blood pressure, automated reading	0.6	1.8	6.6	0.5	2.6	-0.3	2.4	0.0	-0.0	-1.3	-0.4	-1.2
Severe depression (siblings)	0.6	0.6	3.5	-0.7	-0.7	-0.6	-0.3	-1.9	-0.1	0.1	-0.5	-0.7
Impedance of leg (right)	0.6	3.1	6.3	-1.6	-1.2	-1.9	1.1	1.3	-1.2	-2.3	-2.1	-2.5
Relative age voice broke	0.6	0.9	2.7	0.2	-1.4	0.2	1.6	-0.6	1.3	0.7	0.5	0.8
Leg predicted mass (left)	0.6	3.4	6.6	2.0	1.6	2.1	0.7	-1.2	1.3	1.7	2.4	2.6
Trunk fat-free mass	0.6	3.2	7.5	1.8	0.6	2.2	-0.4	-1.5	1.3	1.6	2.5	2.7
Forced expiratory volume in 1-second (FEV1), Best measure	0.6	2.0	5.4	0.3	-0.7	0.9	-2.0	-0.3	0.8	2.2	1.2	2.3
Impedance of arm (left)	0.6	2.8	5.4	-1.5	-1.5	-2.2	1.9	1.7	-0.3	-1.0	-1.8	-2.3
Trunk predicted mass	0.6	3.4	8.1	1.9	0.7	2.3	-0.4	-1.4	1.3	1.7	2.6	2.8
Exposure to tobacco smoke at home	0.6	0.6	1.6	1.0	0.6	0.9	-1.0	0.1	-0.8	-1.3	0.5	-0.4
Breastfed as a baby	0.6	0.8	1.8	1.3	0.4	1.2	1.2	0.2	0.9	0.2	1.0	0.6
Birth weight of first child	0.6	1.0	3.4	1.2	-1.1	0.8	1.8	0.9	-0.3	-0.6	0.9	0.6
Pulse wave reflection index	0.6	0.7	3.0	-1.2	-0.8	-0.6	-1.7	-0.1	0.1	0.0	-0.8	-0.5
Ever highly irritable/argumentative for 2 days	0.6	0.7	3.0	-0.8	1.7	-0.4	-0.6	0.2	-1.1	0.1	-0.8	-0.1
Glaucoma (self-reported)	0.6	0.7	1.9	-0.5	0.9	0.0	-1.3	1.1	-1.4	0.0	-0.6	0.3
Birth weight	0.6	1.2	5.4	1.1	-0.9	0.5	0.7	2.3	-0.3	-1.4	0.6	0.8
Average weekly red wine intake	0.6	0.8	5.2	0.6	-0.5	0.7	-2.3	-0.4	0.6	0.2	0.6	0.2
Breast cancer (self-reported)	0.6	0.7	3.9	-0.2	2.0	0.1	0.0	-0.1	-1.2	0.4	-0.4	0.5
Illnesses of father: None of the above (group 1)	0.6	0.7	2.0	-1.4	-0.3	-0.7	-1.0	-0.3	-1.4	0.2	-0.9	-0.4
Medication: Blood pressure	0.6	1.2	3.8	1.9	0.7	1.3	0.2	0.1	1.3	-0.8	1.4	0.8
Medication: Lisinopril	0.6	0.8	1.9	1.2	1.4	0.7	1.3	-0.3	0.6	0.3	1.1	0.5
Irritability	0.6	1.0	2.1	-1.4	-1.0	-1.4	-0.2	-0.9	-0.8	-0.6	-1.2	-1.0
Bipolar Disorder (2018)	0.5	0.8	2.1	-0.9	-0.7	-0.6	-1.4	-0.9	-1.2	0.7	-0.8	-0.4
Depressed Affect (Nagel 2018)	0.5	1.1	2.0	-1.2	-0.5	-1.4	1.2	0.6	-1.0	-0.3	-1.2	-1.3
Alzheimer’s Disease (in father)	0.5	0.6	3.6	0.5	-0.4	0.3	-1.9	0.9	0.2	-0.3	0.2	-0.4
Irritable Bowel Disease (IBD)	0.5	1.1	3.8	-1.1	-1.9	-1.1	-1.3	-0.2	0.3	0.4	-0.8	-1.0
Lupus	0.5	0.7	1.4	1.2	1.2	1.0	-0.3	-0.5	0.4	-1.0	0.7	0.7
Type 2 Diabetes (T2D) (2018)	0.5	1.0	7.6	0.7	2.8	0.3	0.0	-0.2	-0.8	-0.2	0.1	0.2
Hearing difficulty/problems: Yes	0.5	0.7	3.1	-0.4	-0.4	-0.2	1.7	-0.9	0.4	1.1	-0.2	-0.8
Relative age of first facial hair	0.5	1.1	4.3	-0.9	-1.6	-1.1	2.1	-0.3	0.3	-0.1	-0.7	-0.1
Eye problems/disorders: Diabetes related eye disease	0.5	0.6	2.2	-0.2	-0.9	-0.6	-1.5	-1.1	-0.4	0.0	-0.3	0.4
Medication: Metformin	0.5	0.7	3.3	-0.2	1.8	-0.1	-1.1	-0.6	-1.1	0.1	-0.6	-0.4
Hair/balding pattern: Pattern 2	0.5	0.7	1.6	1.3	0.4	1.1	-1.2	0.1	0.7	-0.7	0.8	0.2
Heel bone mineral density (BMD) T-score, automated (right)	0.5	1.3	3.1	-1.1	1.8	-0.7	1.3	1.0	-1.2	0.6	-1.0	-1.1
Pain all over the body in last month	0.5	0.6	2.0	-0.2	1.1	0.5	0.6	-0.2	-0.9	1.4	0.1	0.4
Depression (self-reported)	0.5	0.6	2.6	0.0	0.1	-0.3	0.5	-0.2	-0.6	-1.3	-0.3	-1.6
Hair/balding pattern: Pattern 4	0.5	1.2	3.4	-0.3	-0.8	0.2	-1.8	-1.3	0.4	1.8	0.5	1.0
Blood clot in the leg (DVT)	0.5	0.7	2.7	-0.3	0.9	-0.3	1.6	0.6	0.3	1.1	-0.2	0.6
Shortness of breath walking on level ground	0.5	0.6	1.7	0.5	-1.2	0.2	-0.7	1.3	0.1	0.8	0.3	0.7
Eye problems/disorders: None of the above	0.5	0.6	1.1	-0.6	-1.0	-0.8	0.3	-0.5	0.0	-0.9	-0.8	-1.0
Migraine (self-reported)	0.5	0.6	1.9	1.0	0.8	1.4	-0.8	0.4	-0.6	-0.5	0.5	0.0
Alcohol intake frequency.	0.5	1.3	8.9	-0.5	3.0	-0.1	0.5	-0.1	-0.3	1.3	-0.5	0.0
Had major operations	0.5	0.6	2.2	0.4	0.4	0.7	-0.9	-0.0	0.6	1.5	0.8	1.0
Ever had bowel cancer screening	0.5	0.6	2.7	0.9	0.3	0.8	-1.6	-0.2	0.2	-0.4	0.7	-0.6
Miserableness	0.5	0.8	2.3	-0.2	-1.3	-0.8	1.5	0.9	0.5	-0.8	-0.1	-0.8
Financial situation satisfaction	0.5	0.6	3.2	-0.3	-1.8	-0.1	-0.8	-0.3	-0.8	-0.7	-0.5	-0.5
Commuting to job workplace: Public transport	0.5	0.6	2.1	0.4	0.4	0.3	-1.4	1.5	-0.5	0.5	0.4	0.5
Ever smoked	0.5	0.9	3.8	0.4	-1.5	0.0	1.1	0.5	2.0	-0.3	0.7	0.2
Pain experienced in last month	0.5	0.8	3.4	0.0	-1.1	-0.5	1.8	0.5	1.3	0.2	0.4	0.6
Deep venous thrombosis (DVT) (self-reported)	0.5	0.6	2.7	-0.4	1.2	-0.5	1.6	0.4	-0.0	0.9	-0.5	0.2
Impedance of whole body	0.5	2.7	4.9	-1.3	-1.3	-1.9	1.5	2.0	-0.5	-1.6	-1.7	-2.2
Major Depression (MDD)	0.4	0.4	1.2	0.0	-1.1	0.1	1.1	0.5	0.8	0.6	0.3	0.5
HDL Cholesterol	0.4	0.7	1.3	-0.6	-1.1	-0.9	0.8	0.7	-0.6	-0.9	-0.7	-1.2
Ulcerative Colitis	0.4	0.6	2.8	-0.2	-1.7	-0.2	-1.3	-0.9	0.1	-0.2	-0.1	-0.2
Systolic Blood Pressure	0.4	2.1	5.2	0.2	1.6	-1.2	2.3	0.4	-0.1	-2.2	-0.9	-2.0
Average weekly spirits intake	0.4	0.5	1.7	-0.4	1.3	-0.4	1.3	-0.2	-0.6	-0.2	-0.1	0.6
Sensitivity / hurt feelings	0.4	0.7	3.1	-0.4	0.0	-0.7	-0.7	-0.6	-0.5	-1.8	-0.9	-1.0
Ever had hysterectomy (womb removed)	0.4	0.4	1.4	-0.2	-0.4	0.2	-0.9	-0.9	-0.2	0.6	-0.1	1.2
Vitamin and mineral supplements	0.4	0.5	2.0	-0.1	-0.2	0.1	0.6	1.2	0.5	1.4	0.4	0.8
Diabetes (mother)	0.4	0.6	1.8	1.3	0.5	1.1	-0.6	0.3	0.3	0.5	0.9	0.4
Maternal smoking around birth	0.4	0.6	3.8	0.5	0.5	0.6	2.0	-0.3	-0.0	0.4	0.4	0.0
Bilateral oophorectomy (both ovaries removed)	0.4	0.5	1.5	-0.2	-0.2	0.1	-1.2	0.4	0.0	1.2	0.2	1.1
Impedance of leg (left)	0.4	1.7	4.2	-1.1	-1.3	-1.3	0.7	2.0	-0.4	-1.4	-1.3	-1.5
Number of incorrect matches in round	0.4	0.7	2.5	-0.1	-1.6	0.0	1.5	1.1	-0.3	-0.3	-0.1	-0.4
Illnesses of siblings	0.4	0.5	3.7	0.1	-1.9	0.3	-0.3	0.5	-0.1	-0.1	0.4	0.4
Hair/balding pattern: Pattern 3	0.4	0.7	2.6	-0.2	0.1	0.1	1.3	0.9	0.4	1.6	0.3	0.6
Peak expiratory flow (PEF)	0.4	0.8	1.9	0.4	0.7	1.1	-1.2	-0.5	0.0	1.4	0.9	1.2
Medication: Blood pressure	0.4	0.8	1.7	1.3	1.0	1.0	0.8	-0.9	1.0	-0.5	0.6	-0.3
Osteoporosis (self-reported)	0.4	0.5	1.3	-0.3	0.4	-0.3	-0.1	-1.0	-0.2	-1.1	-0.9	-1.1
Age started oral contraceptive pill	0.4	0.6	3.2	0.2	0.3	0.4	-1.8	-1.2	-0.2	0.3	-0.1	-0.2
Lung FEV1/FVC ratio	0.3	1.5	3.7	1.2	1.9	1.3	0.2	-0.4	1.4	1.2	1.2	1.0
Supplements: Zinc	0.3	0.3	0.8	0.8	-0.1	0.3	-0.2	0.9	0.6	-0.1	0.8	0.1
Stomach or abdominal pain in last month	0.3	0.4	1.2	-0.3	-0.2	-0.5	-0.1	-0.9	-1.1	-0.8	-0.4	-0.1
Medication: Lansoprazole	0.3	0.3	1.1	0.8	0.1	0.5	0.0	0.3	0.7	0.1	0.7	1.1
Forced vital capacity (FVC), Best measure	0.3	1.2	3.7	0.2	-1.3	0.6	-1.3	-0.2	0.4	1.4	1.0	1.9
Comparative body size at age 10	0.3	0.9	3.6	1.3	1.9	0.9	0.9	0.6	0.4	-0.3	0.7	-0.5
Medication: Aspirin	0.3	0.4	1.2	0.7	1.1	0.7	1.0	0.2	-0.0	-0.1	0.4	-0.1
Supplements: Vitamin C	0.3	0.4	3.0	-0.2	1.7	0.0	-0.6	0.0	-0.0	-0.3	-0.1	-0.3
Forced expiratory volume in 1-second (FEV1), predicted	0.3	0.5	1.8	-0.6	-1.3	-0.7	-0.4	-0.9	-0.1	0.9	-0.1	0.4
Qualifications: nursing, teaching	0.3	0.5	1.3	0.4	-0.5	0.8	-0.9	-1.1	0.6	0.8	0.7	-0.1
Medication: Aspirin	0.3	0.4	1.3	0.3	1.1	0.2	1.1	0.2	-0.7	-0.6	-0.0	-0.2
Ever had prostate specific antigen (PSA) test	0.3	0.4	1.6	-0.2	0.4	-0.1	-0.6	-0.0	-1.1	-0.1	-0.5	-1.3
Myopia	0.3	0.4	1.2	0.1	-1.1	0.1	1.0	0.9	0.1	-0.1	-0.2	-0.9
Ulcerative Colitis (UC)	0.2	0.3	1.3	-0.4	-1.1	-0.5	-0.8	-0.1	0.5	0.6	-0.1	-0.1
Ovarian Cancer	0.2	0.2	0.8	0.3	0.1	0.0	0.3	0.7	-0.3	-0.3	0.3	0.9
Crohns Disease (2012)	0.2	0.4	1.1	-0.9	-0.4	-0.3	-1.0	0.6	-0.2	0.8	-0.6	-0.0
Heel T-Score	0.2	1.9	5.6	-0.9	2.4	-0.7	2.2	-1.5	-0.8	-0.4	-0.9	-1.3
Lung FVC	0.2	0.8	2.4	-1.3	0.4	-0.6	-1.6	-0.6	-0.8	1.1	-0.8	0.4
Serious illness, injury or assault to yourself	0.2	0.2	0.7	0.1	-0.2	0.5	-0.7	0.3	-0.7	0.8	-0.0	-0.3
High blood pressure (mother)	0.2	0.3	1.5	-0.3	0.4	-0.7	0.2	0.3	0.5	-0.2	-0.6	-1.2
Ever unenthusiastic/disinterested for a whole week	0.2	0.2	0.5	-0.3	-0.3	-0.5	-0.7	0.2	-0.6	-0.7	-0.5	-0.2
Alcohol intake versus 10 years previously	0.2	0.4	1.4	0.6	1.2	0.5	-0.6	0.4	-0.8	-0.0	0.1	-0.0
Frequency of tiredness / lethargy in last 2 weeks	0.2	0.4	2.0	0.2	-0.9	0.2	1.4	0.2	0.2	0.1	0.4	0.4
Forced expiratory volume in 1-second (FEV1)	0.2	0.7	1.8	-0.2	-0.1	0.4	-1.4	-1.0	-0.0	1.2	0.5	1.4
Mouth/teeth dental problems: Dentures	0.2	0.3	1.7	-0.1	1.3	0.0	1.0	-0.1	-0.2	0.1	-0.1	0.2
Standing height	0.2	1.9	4.4	1.1	-2.1	1.1	0.7	-0.2	1.5	0.8	1.8	1.9
High blood pressure (siblings)	0.2	0.2	1.1	-0.2	0.2	-0.6	0.4	-0.6	0.2	-0.3	-0.4	-1.0
Health satisfaction	0.2	0.2	1.3	0.5	-1.1	0.3	-0.3	0.5	-0.2	-0.4	0.0	0.4
Neck or shoulder pain in last month	0.2	0.3	1.5	-0.4	0.1	-0.2	-1.2	-0.7	-0.2	-0.5	-0.4	0.0
Pain type(s) experienced in last month: Hip pain	0.2	0.3	1.4	-0.0	0.9	0.2	1.2	0.1	0.0	0.6	0.1	0.2
Average weekly beer plus cider intake	0.2	0.3	0.8	0.8	0.1	0.4	-0.7	-0.2	0.1	-0.6	0.5	0.9
Alcohol drinker status: Previous	0.2	0.2	0.8	-0.1	-0.2	-0.1	0.9	-0.3	0.6	0.6	0.0	0.1
Bipolar Disorder (2011)	0.1	0.1	0.9	0.0	0.0	0.0	0.0	0.0	0.0	0.3	-1.0	-0.4
Height	0.1	2.6	6.6	1.0	-2.6	1.1	1.1	-0.1	1.8	1.3	2.0	2.1
Fed-up feelings	0.1	0.1	0.4	-0.3	-0.0	-0.4	0.6	0.5	-0.0	-0.4	-0.1	-0.5
Sitting height	0.1	0.7	4.0	-0.5	-0.4	-0.3	-2.0	-1.0	-0.4	-0.1	0.0	0.8
Forced vital capacity (FVC)	0.1	0.4	0.8	-0.6	-0.4	0.0	-0.9	-0.8	-0.7	0.5	-0.1	0.7
Financial difficulties in last 2 years	0.1	0.2	1.0	-0.4	-0.1	-0.1	-0.3	0.2	-0.2	1.0	0.1	0.1
Medication: Ramipril	0.1	0.2	0.6	-0.3	0.2	-0.5	-0.6	0.3	0.8	0.2	-0.2	-0.3
Number of full brothers	0.1	0.1	0.4	-0.0	0.2	0.2	-0.0	-0.6	0.4	0.5	0.0	-0.0
Comparative height size at age 10	0.1	0.6	1.6	0.8	-0.5	0.7	1.3	-0.6	0.5	-0.2	0.9	0.8
Knee pain experienced in last month	0.1	0.2	0.8	0.1	-0.2	-0.1	-0.9	-0.7	0.5	-0.2	-0.0	-0.1
Fractured/broken bones in last 5 years	0.1	0.1	0.5	0.1	-0.3	-0.0	-0.7	0.0	-0.2	-0.0	-0.1	0.0
Hair Pigment	0.0	0.5	2.3	0.0	1.5	0.1	1.2	-0.5	0.0	-0.3	-0.2	0.6
Tanning	0.0	0.3	0.9	0.9	-0.3	0.9	0.2	-0.0	-0.5	-0.4	0.7	0.5

Hub : Genes

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Trait associations