Best TWAS P=2.16e-10 · Best GWAS P=1.61e-09 conditioned to 0.000325
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Esophagus Gastroesophageal Junction | MKRN2 | 0.17 | 0.10 | enet | 13 | 0.07 | 1.9e-03 | -4.6 | -5.2 | 2.3e-07 | -0.17 | 0.27 | 0.12 | TRUE |
2 | METSIM | Adipose | TSEN2 | 0.06 | 0.02 | enet | 30 | 0.06 | 9.3e-10 | -5.5 | 6.3 | 2.2e-10 | 0.42 | 0.09 | 0.91 | TRUE |