[Hub]/) : Traits : High cholesterol (Self-reported) : ← →

chr2:202,434,393-204,433,184

Best TWAS P=9.84e-12 · Best GWAS P=1.05e-10 conditioned to 0.0437

Associated models

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	CommonMind	Brain Pre-frontal Cortex	FAM117B	0.13	0.09	lasso	13	0.11	2.7e-13	-4.8	5.5	3.5e-08	0.17	0.98	0.02	FALSE
2	CommonMind	Brain Pre-frontal Cortex	NOP58	0.05	0.02	blup	365	0.03	3.2e-04	5.7	6.8	9.8e-12	0.75	0.08	0.82	TRUE
3	GTEx	Artery Aorta	RP11-686O6.2	0.14	0.09	enet	10	0.07	1.7e-04	6.4	6.5	6.1e-11	0.91	0.02	0.98	FALSE
4	GTEx	Artery Coronary	RP11-686O6.2	0.13	0.09	lasso	2	0.04	1.3e-02	6.2	6.2	6.7e-10	0.99	0.01	0.93	FALSE
5	GTEx	Artery Tibial	RP11-686O6.2	0.14	0.08	lasso	8	0.11	8.5e-09	6.5	6.6	4.4e-11	0.95	0.02	0.98	FALSE
6	GTEx	Cells Transformed fibroblasts	RP11-686O6.2	0.16	0.17	lasso	3	0.17	1.7e-12	6.2	6.0	2.4e-09	0.98	0.02	0.98	FALSE
7	GTEx	Esophagus Gastroesophageal Junction	RP11-686O6.2	0.19	0.11	lasso	4	0.06	2.5e-03	5.7	6.2	7.5e-10	0.97	0.02	0.96	FALSE
8	GTEx	Esophagus Mucosa	RP11-686O6.2	0.07	0.05	lasso	2	0.02	1.0e-02	5.7	5.9	4.5e-09	0.94	0.04	0.91	FALSE
9	GTEx	Esophagus Muscularis	RP11-686O6.2	0.18	0.11	lasso	5	0.10	7.9e-07	6.4	6.3	3.8e-10	0.99	0.01	0.99	FALSE
10	GTEx	Lung	RP11-686O6.2	0.19	0.14	lasso	7	0.13	6.4e-10	6.4	6.7	3.0e-11	0.95	0.01	0.99	FALSE
11	GTEx	Muscle Skeletal	NOP58	0.06	0.01	lasso	3	0.00	1.2e-01	6.4	6.4	1.9e-10	0.99	0.02	0.97	FALSE
12	GTEx	Muscle Skeletal	RP11-686O6.2	0.05	0.03	lasso	2	0.03	5.1e-04	5.7	5.7	1.4e-08	0.95	0.03	0.94	FALSE
13	GTEx	Nerve Tibial	RP11-686O6.2	0.07	0.05	enet	8	0.05	1.9e-04	6.4	6.2	4.1e-10	0.97	0.01	0.99	FALSE
14	GTEx	Pancreas	ICA1L	0.17	0.07	lasso	8	0.10	4.9e-05	5.5	-6.3	3.4e-10	-0.84	0.04	0.81	FALSE
15	GTEx	Prostate	RP11-686O6.2	0.42	0.08	enet	21	0.03	4.9e-02	6.4	5.1	2.8e-07	0.78	0.02	0.66	FALSE
16	GTEx	Skin Not Sun Exposed Suprapubic	ICA1L	0.10	0.02	lasso	3	0.03	8.8e-03	-3.7	-5.2	1.5e-07	-0.25	0.08	0.21	FALSE
17	METSIM	Adipose	RP11-686O6.2	0.03	0.04	lasso	1	0.03	1.2e-05	5.7	5.7	1.2e-08	0.84	0.04	0.96	FALSE
18	NTR	Blood	NOP58	0.02	0.01	blup	359	0.01	2.4e-04	5.7	5.2	1.8e-07	0.72	0.02	0.96	FALSE
19	The Cancer Genome Atlas	Prostate Adenocarcinoma	NOP58	0.05	0.06	lasso	4	0.05	1.3e-05	5.7	5.7	1.6e-08	0.94	0.02	0.98	FALSE