Best TWAS P=1.44e-09 · Best GWAS P=7.37e-11 conditioned to 0.0155
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | NAT2 | 0.04 | 0.04 | lasso | 2 | 0.03 | 0.00024 | 6.1 | -6.0 | 1.4e-09 | -0.94 | 0.02 | 0.96 | TRUE |
2 | The Cancer Genome Atlas | Brain Lower Grade Glioma | NAT2 | 0.03 | 0.01 | lasso | 2 | 0.01 | 0.02340 | 5.1 | -5.2 | 1.6e-07 | -0.70 | 0.06 | 0.58 | FALSE |