Best TWAS P=1.62e-10 · Best GWAS P=1.34e-10 conditioned to 0.105
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Esophagus Mucosa | COL4A3BP | 0.09 | 0.06 | lasso | 5 | 0.05 | 0.00042 | 5.5 | -5.3 | 1.5e-07 | -0.69 | 0.18 | 0.78 | FALSE |
| 2 | The Cancer Genome Atlas | Ovarian Serous Cystadenocarcinoma | HMGCR | 0.04 | 0.02 | enet | 4 | 0.03 | 0.00600 | 6.4 | 6.4 | 1.6e-10 | 0.89 | 0.00 | 0.92 | TRUE |