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Medication: Simvastatin
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chr5:73,969,058-75,504,243
Best TWAS P=1.62e-10 · Best GWAS P=1.34e-10 conditioned to 0.105
74M
74.2M
74.4M
74.6M
74.8M
75M
75.2M
75.4M
0
2
4
6
8
10
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
2
The Cancer Genome Atlas
Ovarian Serous Cystadenocarcinoma
HMGCR
0.04
0.02
enet
4
0.03
0.00600
6.4
6.4
1.6e-10
0.89
0.00
0.92
TRUE
1
GTEx
Esophagus Mucosa
COL4A3BP
0.09
0.06
lasso
5
0.05
0.00042
5.5
-5.3
1.5e-07
-0.69
0.18
0.78
FALSE