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chr15:90,730,363-92,135,418

Best TWAS P=2.28e-10 · Best GWAS P=6.13e-08 conditioned to 0.599

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Artery Tibial FES 0.16 0.04 lasso 5 0.05 4.8e-05 4.6 -5.5 3.5e-08 -0.73 0.05 0.94 FALSE
2 GTEx Cells Transformed fibroblasts FES 0.28 0.17 enet 21 0.20 2.8e-15 4.8 -5.6 2.0e-08 -0.90 0.01 0.99 FALSE
3 GTEx Lung FES 0.24 0.07 lasso 6 0.05 5.1e-05 4.6 -5.4 6.2e-08 -0.79 0.05 0.93 FALSE
4 The Cancer Genome Atlas Bladder Urothelial Carcinoma FES 0.06 0.05 blup 46 0.06 1.9e-05 5.4 -5.3 1.3e-07 -0.83 0.00 0.99 FALSE
5 The Cancer Genome Atlas Breast Invasive Carcinoma FES 0.06 0.05 blup 46 0.07 7.4e-14 4.8 -6.3 2.3e-10 -0.89 0.01 0.99 TRUE
6 The Cancer Genome Atlas Cervical Squamous Cell Carcinoma FES 0.06 0.02 blup 46 0.02 2.4e-02 4.8 -5.2 2.5e-07 -0.77 0.01 0.73 FALSE
7 The Cancer Genome Atlas Head and Neck Squamous Cell Carcinoma FES 0.06 0.03 blup 46 0.05 5.6e-06 5.4 -5.5 3.5e-08 -0.81 0.01 0.98 FALSE
8 The Cancer Genome Atlas Kidney Renal Clear Cell Carcinoma FES 0.10 0.07 enet 5 0.05 2.8e-06 5.4 -5.2 1.9e-07 -0.99 0.00 1.00 FALSE
9 The Cancer Genome Atlas Lung Adenocarcinoma FES 0.05 0.04 lasso 2 0.04 2.2e-05 4.8 -5.5 4.3e-08 -0.90 0.01 0.99 FALSE
10 The Cancer Genome Atlas Lung Squamous Cell Carcinoma FES 0.08 0.07 enet 7 0.08 4.2e-09 4.8 -5.4 5.8e-08 -0.82 0.06 0.94 FALSE
11 The Cancer Genome Atlas Prostate Adenocarcinoma FES 0.12 0.09 lasso 5 0.08 4.1e-09 4.8 -5.6 1.8e-08 -0.80 0.05 0.94 FALSE
12 The Cancer Genome Atlas Stomach Adenocarcinoma FES 0.04 0.01 blup 46 0.02 1.7e-02 5.4 -6.1 9.4e-10 -0.78 0.01 0.61 FALSE
13 The Cancer Genome Atlas Thyroid Carcinoma FES 0.30 0.30 lasso 7 0.32 1.3e-31 4.6 -5.4 7.1e-08 -0.84 0.12 0.87 FALSE