57 significantly associated models · 24 unique genes
.
# | chr | p0 | p1 | # assoc genes | # joint genes | best TWAS P | best SNP P | cond SNP P | % var exp | joint genes |
---|---|---|---|---|---|---|---|---|---|---|
1 | 1 | 10435170 | 12156236 | 2 | 2 | 4.4e-09 | 8.5e-21 | 7.6e-13 | 41 | CLCN6 RP4-635E18.7 |
2 | 1 | 27013133 | 28406173 | 1 | 1 | 9.0e-08 | 1.1e-05 | 5.4e-01 | 98 | CD164L2 |
3 | 1 | 112312154 | 113907148 | 5 | 2 | 1.8e-12 | 9.4e-15 | 1.1e-07 | 53 | CTTNBP2NL RHOC |
4 | 2 | 26291565 | 27689899 | 1 | 1 | 1.3e-07 | 6.2e-12 | 8.8e-07 | 49 | SLC35F6 |
5 | 3 | 26720690 | 28211713 | 1 | 1 | 1.8e-07 | 5.3e-07 | 2.3e-03 | 63 | SLC4A7 |
6 | 11 | 1213806 | 2640824 | 2 | 2 | 4.4e-12 | 4.1e-12 | 1.5e-01 | 96 | LSP1 TNNT3 |
7 | 11 | 99859184 | 101559718 | 2 | 1 | 1.4e-09 | 4.8e-09 | 2.2e-01 | 96 | TMEM133 |
8 | 12 | 121146219 | 122706844 | 2 | 1 | 1.6e-07 | 8.8e-08 | 1.0e+00 | 100 | RNF34 |
9 | 15 | 90730363 | 92135418 | 1 | 1 | 2.3e-10 | 6.1e-08 | 6.0e-01 | 99 | FES |
10 | 17 | 7269373 | 7784295 | 1 | 1 | 7.0e-08 | 5.7e-07 | 3.9e-03 | 67 | SHBG |
11 | 17 | 25990033 | 27387415 | 1 | 1 | 2.6e-07 | 5.9e-06 | 1.1e-04 | 27 | TMEM199 |
12 | 17 | 55903829 | 57920532 | 5 | 1 | 7.1e-09 | 2.9e-08 | 2.9e-02 | 84 | SKA2 |
Trait | chisq ratio | # genes+ | # genes++ | % genes++ | corr | corr P | genes |
---|
study | tissue | # hits | % hits/tests | avg chisq |
---|
study | tissue | # hits | % hits/tests | avg chisq |
---|---|---|---|---|
The Cancer Genome Atlas | Uterine Corpus Endometrial Carcinoma | 0 | 0.000 | 1.6 |
GTEx | Adipose Subcutaneous | 1 | 0.029 | 1.5 |
GTEx | Adipose Visceral Omentum | 0 | 0.000 | 1.5 |
GTEx | Adrenal Gland | 1 | 0.069 | 1.5 |
GTEx | Artery Aorta | 3 | 0.101 | 1.5 |
GTEx | Artery Coronary | 0 | 0.000 | 1.5 |
GTEx | Artery Tibial | 4 | 0.106 | 1.5 |
GTEx | Brain Hippocampus | 0 | 0.000 | 1.5 |
GTEx | Breast Mammary Tissue | 0 | 0.000 | 1.5 |
GTEx | Breast Mammary Tissue (Female) | 0 | 0.000 | 1.5 |
GTEx | Colon Sigmoid | 0 | 0.000 | 1.5 |
GTEx | Colon Transverse | 0 | 0.000 | 1.5 |
GTEx | Esophagus Gastroesophageal Junction | 0 | 0.000 | 1.5 |
GTEx | Esophagus Muscularis | 0 | 0.000 | 1.5 |
GTEx | Lung | 2 | 0.070 | 1.5 |
GTEx | Ovary | 0 | 0.000 | 1.5 |
GTEx | Pancreas | 0 | 0.000 | 1.5 |
GTEx | Prostate | 0 | 0.000 | 1.5 |
GTEx | Skin Not Sun Exposed Suprapubic | 1 | 0.041 | 1.5 |
GTEx | Spleen | 0 | 0.000 | 1.5 |
GTEx | Stomach | 1 | 0.069 | 1.5 |
GTEx | Vagina | 0 | 0.000 | 1.5 |
ROSMAP | Brain Pre-frontal Cortex | 2 | 0.046 | 1.5 |
GTEx | Brain Caudate basal ganglia | 0 | 0.000 | 1.4 |
GTEx | Brain Cerebellum | 0 | 0.000 | 1.4 |
GTEx | Brain Cortex | 0 | 0.000 | 1.4 |
GTEx | Brain Frontal Cortex BA9 | 0 | 0.000 | 1.4 |
GTEx | Brain Hypothalamus | 0 | 0.000 | 1.4 |
GTEx | Brain Nucleus accumbens basal ganglia | 0 | 0.000 | 1.4 |
GTEx | Breast Mammary Tissue (Male) | 1 | 0.084 | 1.4 |
GTEx | Cells EBV-transformed lymphocytes | 0 | 0.000 | 1.4 |
GTEx | Cells Transformed fibroblasts | 3 | 0.071 | 1.4 |
GTEx | Esophagus Mucosa | 0 | 0.000 | 1.4 |
GTEx | Heart Atrial Appendage | 0 | 0.000 | 1.4 |
GTEx | Heart Left Ventricle | 0 | 0.000 | 1.4 |
GTEx | Muscle Skeletal | 2 | 0.069 | 1.4 |
GTEx | Nerve Tibial | 3 | 0.069 | 1.4 |
GTEx | Pituitary | 0 | 0.000 | 1.4 |
GTEx | Skin Sun Exposed Lower leg | 0 | 0.000 | 1.4 |
GTEx | Small Intestine Terminal Ileum | 0 | 0.000 | 1.4 |
GTEx | Testis | 1 | 0.032 | 1.4 |
GTEx | Thyroid | 0 | 0.000 | 1.4 |
GTEx | Uterus | 0 | 0.000 | 1.4 |
GTEx | Whole Blood | 1 | 0.050 | 1.4 |
METSIM | Adipose | 2 | 0.043 | 1.4 |
NTR | Blood | 0 | 0.000 | 1.4 |
CommonMind | Brain Pre-frontal Cortex | 2 | 0.037 | 1.4 |
The Cancer Genome Atlas | Breast Invasive Carcinoma | 2 | 0.045 | 1.4 |
The Cancer Genome Atlas | Cervical Squamous Cell Carcinoma | 2 | 0.182 | 1.4 |
The Cancer Genome Atlas | Colon Adenocarcinoma | 0 | 0.000 | 1.4 |
The Cancer Genome Atlas | Glioblastoma Multiforme | 0 | 0.000 | 1.4 |
The Cancer Genome Atlas | Head and Neck Squamous Cell Carcinoma | 4 | 0.147 | 1.4 |
The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | 3 | 0.073 | 1.4 |
The Cancer Genome Atlas | Kidney Renal Papillary Cell Carcinoma | 1 | 0.049 | 1.4 |
The Cancer Genome Atlas | Brain Lower Grade Glioma | 1 | 0.023 | 1.4 |
The Cancer Genome Atlas | Liver Hepatocellular Carcinoma | 1 | 0.090 | 1.4 |
The Cancer Genome Atlas | Lung Adenocarcinoma | 2 | 0.068 | 1.4 |
The Cancer Genome Atlas | Lung Squamous Cell Carcinoma | 2 | 0.080 | 1.4 |
The Cancer Genome Atlas | Ovarian Serous Cystadenocarcinoma | 1 | 0.063 | 1.4 |
The Cancer Genome Atlas | Pancreatic Adenocarcinoma | 0 | 0.000 | 1.4 |
The Cancer Genome Atlas | Prostate Adenocarcinoma | 1 | 0.022 | 1.4 |
The Cancer Genome Atlas | Rectum Adenocarcinoma | 0 | 0.000 | 1.4 |
The Cancer Genome Atlas | Soft Tissue Sarcoma | 0 | 0.000 | 1.4 |
The Cancer Genome Atlas | Stomach Adenocarcinoma | 1 | 0.059 | 1.4 |
GTEx | Brain Cerebellar Hemisphere | 0 | 0.000 | 1.3 |
GTEx | Brain Putamen basal ganglia | 0 | 0.000 | 1.3 |
GTEx | Liver | 0 | 0.000 | 1.3 |
YFS | Blood | 1 | 0.022 | 1.3 |
The Cancer Genome Atlas | Bladder Urothelial Carcinoma | 2 | 0.121 | 1.3 |
The Cancer Genome Atlas | Esophageal Carcinoma | 0 | 0.000 | 1.3 |
The Cancer Genome Atlas | Pheochromocytoma and Paraganglioma | 0 | 0.000 | 1.3 |
The Cancer Genome Atlas | Skin Cutaneous Melanoma | 0 | 0.000 | 1.3 |
The Cancer Genome Atlas | Testicular Germ Cell Tumors | 0 | 0.000 | 1.3 |
The Cancer Genome Atlas | Thyroid Carcinoma | 3 | 0.058 | 1.3 |