Best TWAS P=1.15e-07 · Best GWAS P=1.39e-07 conditioned to 0.292
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | NTR | Blood | CALR | 0.04 | 0.03 | lasso | 8 | 0.02 | 4.2e-08 | -4.7 | 5.3 | 1.1e-07 | -0.91 | 0.01 | 0.99 | TRUE |
2 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | DAND5 | 0.03 | 0.02 | blup | 31 | 0.03 | 3.0e-04 | -5.3 | 5.1 | 3.1e-07 | -0.80 | 0.00 | 0.95 | FALSE |