Best TWAS P=1.25e-08 · Best GWAS P=1.57e-10 conditioned to 0.00154
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | The Cancer Genome Atlas | Lung Adenocarcinoma | IL1RL1 | 0.03 | 0.01 | blup | 78 | 0.02 | 4.7e-03 | -4.1 | -5.7 | 1.2e-08 | 0.77 | 0.08 | 0.42 | TRUE |
2 | The Cancer Genome Atlas | Pancreatic Adenocarcinoma | IL1RL1 | 0.19 | 0.05 | blup | 78 | 0.10 | 7.1e-05 | 4.9 | -5.5 | 4.9e-08 | 0.68 | 0.03 | 0.91 | FALSE |