Best TWAS P=3.87e-08 · Best GWAS P=1.47e-08 conditioned to 0.122
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Adipose Subcutaneous | SNRPC | 0.13 | 0.13 | enet | 21 | 0.13 | 1.2e-10 | 4.9 | -5.4 | 6.3e-08 | -0.85 | 0.08 | 0.91 | FALSE |
2 | GTEx | Adrenal Gland | UHRF1BP1 | 0.32 | 0.26 | enet | 33 | 0.33 | 1.3e-12 | 4.9 | 5.3 | 1.4e-07 | 0.85 | 0.04 | 0.96 | FALSE |
3 | GTEx | Colon Transverse | UHRF1BP1 | 0.42 | 0.28 | lasso | 4 | 0.28 | 1.6e-13 | 4.8 | 5.2 | 2.6e-07 | 0.94 | 0.05 | 0.95 | FALSE |
4 | GTEx | Esophagus Muscularis | UHRF1BP1 | 0.42 | 0.35 | enet | 48 | 0.33 | 1.0e-20 | 4.9 | 5.3 | 1.2e-07 | 0.91 | 0.05 | 0.94 | FALSE |
5 | GTEx | Heart Left Ventricle | UHRF1BP1 | 0.23 | 0.12 | lasso | 7 | 0.22 | 1.2e-11 | 4.8 | 5.4 | 7.6e-08 | 0.87 | 0.05 | 0.95 | FALSE |
6 | GTEx | Stomach | UHRF1BP1 | 0.24 | 0.22 | enet | 20 | 0.23 | 2.2e-11 | 5.7 | 5.5 | 3.9e-08 | 0.92 | 0.01 | 0.99 | TRUE |