[Hub]/) : Traits : Medication: Levothyroxine sodium :

chr6:34,026,489-35,542,476

Best TWAS P=3.87e-08 · Best GWAS P=1.47e-08 conditioned to 0.122

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Adipose Subcutaneous SNRPC 0.13 0.13 enet 21 0.13 1.2e-10 4.9 -5.4 6.3e-08 -0.85 0.08 0.91 FALSE
2 GTEx Adrenal Gland UHRF1BP1 0.32 0.26 enet 33 0.33 1.3e-12 4.9 5.3 1.4e-07 0.85 0.04 0.96 FALSE
3 GTEx Colon Transverse UHRF1BP1 0.42 0.28 lasso 4 0.28 1.6e-13 4.8 5.2 2.6e-07 0.94 0.05 0.95 FALSE
4 GTEx Esophagus Muscularis UHRF1BP1 0.42 0.35 enet 48 0.33 1.0e-20 4.9 5.3 1.2e-07 0.91 0.05 0.94 FALSE
5 GTEx Heart Left Ventricle UHRF1BP1 0.23 0.12 lasso 7 0.22 1.2e-11 4.8 5.4 7.6e-08 0.87 0.05 0.95 FALSE
6 GTEx Stomach UHRF1BP1 0.24 0.22 enet 20 0.23 2.2e-11 5.7 5.5 3.9e-08 0.92 0.01 0.99 TRUE