[Hub]/) : Traits : Medication: Levothyroxine sodium : ← →

chr6:34,026,489-35,542,476

Best TWAS P=3.87e-08 · Best GWAS P=1.47e-08 conditioned to 0.122

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
6	GTEx	Stomach	UHRF1BP1	0.24	0.22	enet	20	0.23	2.2e-11	5.7	5.5	3.9e-08	0.92	0.01	0.99	TRUE
1	GTEx	Adipose Subcutaneous	SNRPC	0.13	0.13	enet	21	0.13	1.2e-10	4.9	-5.4	6.3e-08	-0.85	0.08	0.91	FALSE
5	GTEx	Heart Left Ventricle	UHRF1BP1	0.23	0.12	lasso	7	0.22	1.2e-11	4.8	5.4	7.6e-08	0.87	0.05	0.95	FALSE
4	GTEx	Esophagus Muscularis	UHRF1BP1	0.42	0.35	enet	48	0.33	1.0e-20	4.9	5.3	1.2e-07	0.91	0.05	0.94	FALSE
2	GTEx	Adrenal Gland	UHRF1BP1	0.32	0.26	enet	33	0.33	1.3e-12	4.9	5.3	1.4e-07	0.85	0.04	0.96	FALSE
3	GTEx	Colon Transverse	UHRF1BP1	0.42	0.28	lasso	4	0.28	1.6e-13	4.8	5.2	2.6e-07	0.94	0.05	0.95	FALSE