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Medication: Levothyroxine sodium
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chr6:89,941,356-91,704,536
Best TWAS P=6.23e-25 · Best GWAS P=3.97e-25 conditioned to 1
90M
90.2M
90.4M
90.6M
90.8M
91M
91.2M
91.4M
91.6M
91.8M
0
5
10
15
20
25
physical position
-log10 P
Conditional
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
NTR
Blood
BACH2
0.03
0.02
lasso
3
0.02
2.1e-06
10.4
-10.3
6.2e-25
-1.00
0.00
1.00
TRUE
2
YFS
Blood
BACH2
0.03
0.01
lasso
4
0.01
6.9e-04
5.5
-7.3
3.2e-13
-0.46
0.45
0.46
FALSE