Best TWAS P=8.83e-08 · Best GWAS P=9.29e-08 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Lung | RAB2A | 0.06 | 0.03 | lasso | 6 | 0.02 | 9.1e-03 | 5.3 | 5.3 | 9.2e-08 | 0.98 | 0.02 | 0.96 | FALSE |
| 2 | GTEx | Nerve Tibial | RAB2A | 0.10 | 0.02 | lasso | 6 | 0.02 | 1.4e-02 | 5.2 | 5.1 | 2.7e-07 | 0.97 | 0.02 | 0.96 | FALSE |
| 3 | GTEx | Thyroid | RAB2A | 0.06 | 0.04 | enet | 8 | 0.04 | 9.5e-04 | 5.3 | 5.3 | 8.8e-08 | 1.00 | 0.02 | 0.97 | TRUE |
| 4 | METSIM | Adipose | RAB2A | 0.09 | 0.10 | lasso | 8 | 0.09 | 9.3e-14 | 5.2 | 5.1 | 2.8e-07 | 0.97 | 0.01 | 0.99 | FALSE |
| 5 | The Cancer Genome Atlas | Breast Invasive Carcinoma | RAB2A | 0.01 | 0.02 | lasso | 3 | 0.01 | 7.5e-04 | 5.2 | 5.2 | 2.0e-07 | 0.98 | 0.01 | 0.96 | FALSE |
| 6 | The Cancer Genome Atlas | Liver Hepatocellular Carcinoma | RAB2A | 0.10 | 0.06 | blup | 51 | 0.07 | 3.4e-04 | 5.1 | 5.2 | 1.9e-07 | 0.97 | 0.02 | 0.94 | FALSE |