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Medication: Levothyroxine sodium
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chr1:18,972,776-20,503,710
Best TWAS P=1.32e-08 · Best GWAS P=7.74e-08 conditioned to 4.03e-05
19M
19.2M
19.4M
19.6M
19.8M
20M
20.2M
20.4M
0
2
4
6
physical position
-log10 P
Marginal
▼
Associated models
#
Study
Tissue
Gene
h2
eQTL R2
model
# weights
model R2
model R2 P
eQTL GWAS Z
TWAS Z
TWAS P
Top SNP corr
PP3
PP4
joint
1
GTEx
Thyroid
CAPZB
0.22
0.06
lasso
8
0.15
1.1e-11
-3.1
5.7
1.3e-08
0.25
0.43
0.33
TRUE
2
The Cancer Genome Atlas
Thyroid Carcinoma
CAPZB
0.08
0.06
blup
160
0.07
1.2e-07
-3.3
5.2
2.2e-07
0.27
0.73
0.08
FALSE