Best TWAS P=1.32e-08 · Best GWAS P=7.74e-08 conditioned to 4.03e-05
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Thyroid | CAPZB | 0.22 | 0.06 | lasso | 8 | 0.15 | 1.1e-11 | -3.1 | 5.7 | 1.3e-08 | 0.25 | 0.43 | 0.33 | TRUE |
2 | The Cancer Genome Atlas | Thyroid Carcinoma | CAPZB | 0.08 | 0.06 | blup | 160 | 0.07 | 1.2e-07 | -3.3 | 5.2 | 2.2e-07 | 0.27 | 0.73 | 0.08 | FALSE |