[Hub]/) : Traits : Medication: Levothyroxine sodium : ← →

chr1:107,418,424-109,188,382

Best TWAS P=2.88e-29 · Best GWAS P=2.12e-29 conditioned to 1

#	Study	Tissue	Gene	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
3	GTEx	Thyroid	VAV3	0.36	0.27	lasso	5	0.29	2.7e-22	11.3	11.2	2.9e-29	1.00	0.00	1.00	TRUE
2	GTEx	Nerve Tibial	VAV3	0.20	0.07	lasso	5	0.09	8.8e-07	6.6	6.3	2.2e-10	0.77	0.12	0.87	TRUE
1	GTEx	Lung	VAV3	0.25	0.23	lasso	2	0.23	2.4e-17	9.9	9.7	2.2e-22	0.90	0.98	0.02	FALSE
4	NTR	Blood	VAV3	0.03	0.01	lasso	4	0.01	3.6e-03	9.9	9.4	5.6e-21	0.82	0.10	0.72	FALSE
5	The Cancer Genome Atlas	Thyroid Carcinoma	VAV3	0.09	0.02	enet	13	0.05	1.3e-05	10.2	8.5	2.5e-17	0.87	0.01	0.99	FALSE