Best TWAS P=2.71e-08 · Best GWAS P=7.66e-08 conditioned to 1
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Adipose Visceral Omentum | ULK3 | 0.13 | 0.12 | enet | 8 | 0.11 | 3.3e-06 | 5.4 | 5.6 | 2.7e-08 | 0.98 | 0.01 | 0.98 | TRUE |
2 | GTEx | Lung | CSK | 0.09 | 0.06 | lasso | 3 | 0.05 | 1.4e-04 | 5.2 | 5.2 | 1.7e-07 | 0.95 | 0.02 | 0.98 | FALSE |
3 | GTEx | Muscle Skeletal | UBL7 | 0.06 | 0.02 | lasso | 6 | 0.01 | 3.7e-02 | 5.3 | -5.3 | 1.3e-07 | -0.94 | 0.02 | 0.86 | FALSE |
4 | GTEx | Vagina | COX5A | 0.38 | 0.02 | lasso | 7 | 0.02 | 9.3e-02 | 5.3 | -5.1 | 3.1e-07 | -0.86 | 0.02 | 0.76 | FALSE |
5 | YFS | Blood | CSK | 0.13 | 0.15 | lasso | 11 | 0.16 | 6.7e-51 | 5.3 | 5.3 | 1.3e-07 | 0.90 | 0.01 | 0.99 | FALSE |