Best TWAS P=3.9e-09 · Best GWAS P=1e-10 conditioned to 0.0898
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Skin Sun Exposed Lower leg | KBTBD2 | 0.17 | 0.08 | lasso | 2 | 0.06 | 1.2e-05 | 5.3 | 5.5 | 4.3e-08 | -0.08 | 0.59 | 0.38 | TRUE |
| 2 | GTEx | Thyroid | KBTBD2 | 0.11 | 0.06 | enet | 18 | 0.03 | 2.1e-03 | 5.3 | 5.8 | 8.2e-09 | -0.22 | 0.46 | 0.35 | FALSE |
| 3 | METSIM | Adipose | RP11-225B17.2 | 0.06 | 0.02 | blup | 406 | 0.02 | 1.4e-04 | 3.0 | 5.5 | 3.3e-08 | -0.38 | 0.42 | 0.32 | FALSE |
| 4 | The Cancer Genome Atlas | Thyroid Carcinoma | RP9 | 0.06 | 0.06 | lasso | 3 | 0.04 | 4.8e-05 | -5.8 | 5.9 | 3.9e-09 | -0.89 | 0.00 | 1.00 | TRUE |