Best TWAS P=2.54e-10 · Best GWAS P=6.41e-21 conditioned to 8.18e-16
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Thyroid | EPDR1 | 0.19 | 0.06 | enet | 25 | 0.10 | 4.0e-08 | 4.4 | 5.5 | 3.6e-08 | -0.23 | 0.83 | 0.01 | FALSE |
| 2 | ROSMAP | Brain Pre-frontal Cortex | EPDR1 | 0.17 | 0.06 | lasso | 6 | 0.10 | 2.5e-13 | 3.6 | 5.4 | 7.6e-08 | -0.07 | 1.00 | 0.00 | FALSE |
| 3 | The Cancer Genome Atlas | Kidney Renal Clear Cell Carcinoma | EPDR1 | 0.08 | 0.04 | enet | 3 | 0.05 | 5.4e-06 | 4.4 | 6.3 | 2.5e-10 | -0.25 | 0.86 | 0.00 | TRUE |