Best TWAS P=8.48e-09 · Best GWAS P=1.12e-08 conditioned to 1
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Esophagus Muscularis | DBNL | 0.36 | 0.18 | lasso | 6 | 0.17 | 2.0e-10 | 5.7 | -5.8 | 8.5e-09 | -0.98 | 0 | 1 | TRUE |
| 2 | GTEx | Thyroid | DBNL | 0.13 | 0.09 | lasso | 2 | 0.07 | 2.3e-06 | 5.7 | -5.3 | 1.1e-07 | -0.97 | 0 | 1 | FALSE |
| 3 | ROSMAP | Brain Pre-frontal Cortex | DBNL | 0.41 | 0.23 | lasso | 4 | 0.32 | 1.5e-41 | 5.7 | -5.3 | 1.3e-07 | -0.88 | 0 | 1 | FALSE |
| 4 | The Cancer Genome Atlas | Bladder Urothelial Carcinoma | DBNL | 0.19 | 0.07 | lasso | 2 | 0.06 | 8.6e-06 | 5.7 | -5.7 | 9.6e-09 | -1.00 | 0 | 1 | FALSE |
| 5 | The Cancer Genome Atlas | Breast Invasive Carcinoma | DBNL | 0.17 | 0.06 | lasso | 3 | 0.06 | 2.0e-11 | 5.7 | -5.7 | 1.5e-08 | -0.95 | 0 | 1 | FALSE |
| 6 | The Cancer Genome Atlas | Brain Lower Grade Glioma | DBNL | 0.39 | 0.12 | lasso | 2 | 0.15 | 3.2e-16 | 5.7 | -5.5 | 3.5e-08 | -0.91 | 0 | 1 | FALSE |