Best TWAS P=1.84e-10 · Best GWAS P=1.93e-09 conditioned to 0.0111
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | ROSMAP | Brain Pre-frontal Cortex | CREB3L2 | 0.05 | 0 | enet | 10 | 0.01 | 0.009 | -4.7 | -6.3 | 2.8e-10 | 0.45 | 0.04 | 0.73 | FALSE |
| 2 | The Cancer Genome Atlas | Breast Invasive Carcinoma | CREB3L2 | 0.01 | 0 | blup | 94 | 0.01 | 0.010 | -3.7 | -6.4 | 1.8e-10 | 0.63 | 0.04 | 0.41 | TRUE |