Best TWAS P=7.38e-10 · Best GWAS P=2.58e-12 conditioned to 0.00085
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Muscle Skeletal | KCTD9 | 0.11 | 0.07 | lasso | 5 | 0.06 | 7.9e-07 | -5.6 | -5.9 | 3.0e-09 | 0.83 | 0.15 | 0.85 | FALSE |
2 | The Cancer Genome Atlas | Lung Adenocarcinoma | KCTD9 | 0.03 | 0.01 | blup | 75 | 0.01 | 1.1e-02 | -6.3 | -6.2 | 7.4e-10 | 0.90 | 0.02 | 0.73 | TRUE |