[Hub]/) : Traits : Sitting height :

chr1:77,547,831-79,300,939

Best TWAS P=1.33e-09 · Best GWAS P=3.33e-15 conditioned to 3.57e-10

Associated models

# Study Tissue Gene h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 GTEx Cells EBV-transformed lymphocytes NEXN 0.23 0.10 lasso 3 0.08 1.4e-03 -5.1 -5.3 1.4e-07 -0.13 0.21 0.04 FALSE
2 GTEx Lung GIPC2 0.15 0.09 enet 17 0.12 2.5e-09 -5.8 6.1 1.3e-09 0.19 1.00 0.00 TRUE
3 GTEx Pancreas GIPC2 0.41 0.13 enet 29 0.14 1.1e-06 -4.6 5.2 2.4e-07 0.31 0.65 0.10 FALSE
4 GTEx Spleen GIPC2 0.43 0.07 enet 19 0.22 2.9e-06 -4.5 5.2 1.7e-07 0.22 0.83 0.02 FALSE
5 ROSMAP Brain Pre-frontal Cortex FAM73A 0.09 0.04 enet 19 0.06 9.6e-09 -2.3 5.4 6.8e-08 0.33 0.99 0.01 FALSE
6 The Cancer Genome Atlas Bladder Urothelial Carcinoma DNAJB4 0.05 0.03 lasso 3 0.02 3.3e-03 -4.6 -5.6 2.6e-08 -0.20 0.00 0.99 FALSE
7 The Cancer Genome Atlas Colon Adenocarcinoma GIPC2 0.04 0.01 blup 65 0.00 2.5e-01 -4.2 5.1 2.7e-07 0.28 0.07 0.06 FALSE
8 The Cancer Genome Atlas Kidney Renal Papillary Cell Carcinoma FAM73A 0.14 0.02 enet 14 0.06 3.8e-04 3.3 5.6 2.6e-08 0.11 0.01 0.04 TRUE
9 The Cancer Genome Atlas Thyroid Carcinoma GIPC2 0.07 0.05 blup 64 0.06 1.5e-06 -5.9 5.5 3.9e-08 0.28 0.67 0.02 FALSE