Best TWAS P=1.49e-08 · Best GWAS P=7.92e-12 conditioned to 1.86e-06
# | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | GTEx | Testis | RRAS2 | 0.18 | 0.13 | enet | 19 | 0.15 | 2.7e-07 | -4.3 | 5.3 | 1.1e-07 | 0.20 | 0.96 | 0.02 | FALSE |
2 | YFS | Blood | RRAS2 | 0.16 | 0.14 | enet | 53 | 0.19 | 8.5e-59 | 3.7 | -5.3 | 1.2e-07 | -0.40 | 1.00 | 0.00 | FALSE |
3 | The Cancer Genome Atlas | Pheochromocytoma and Paraganglioma | RRAS2 | 0.13 | 0.01 | blup | 11 | 0.05 | 4.0e-03 | 5.8 | 5.7 | 1.5e-08 | 0.46 | 0.00 | 0.93 | TRUE |