Best TWAS P=6.66e-08 · Best GWAS P=5.07e-08 conditioned to 0.000276
| # | Study | Tissue | Gene | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | GTEx | Cells Transformed fibroblasts | TMEM258 | 0.15 | 0.05 | enet | 15 | 0.07 | 1.1e-05 | -5.1 | -5.4 | 6.7e-08 | 0.39 | 0.02 | 0.98 | TRUE |
| 2 | The Cancer Genome Atlas | Brain Lower Grade Glioma | FADS1 | 0.05 | 0.05 | blup | 53 | 0.04 | 6.8e-05 | -4.6 | 5.2 | 2.2e-07 | -0.56 | 0.03 | 0.96 | FALSE |
| 3 | The Cancer Genome Atlas | Liver Hepatocellular Carcinoma | FADS1 | 0.20 | 0.01 | blup | 51 | 0.07 | 3.2e-04 | -4.9 | 5.2 | 2.4e-07 | -0.64 | 0.03 | 0.87 | FALSE |